EP3911360A4 - Verfahren zur modulation der corticosteroid-reaktion - Google Patents

Verfahren zur modulation der corticosteroid-reaktion Download PDF

Info

Publication number
EP3911360A4
EP3911360A4 EP20741802.1A EP20741802A EP3911360A4 EP 3911360 A4 EP3911360 A4 EP 3911360A4 EP 20741802 A EP20741802 A EP 20741802A EP 3911360 A4 EP3911360 A4 EP 3911360A4
Authority
EP
European Patent Office
Prior art keywords
methods
modulating
corticosteroid response
response
modulating corticosteroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20741802.1A
Other languages
English (en)
French (fr)
Other versions
EP3911360A1 (de
Inventor
Ben ZWEIFEL
Prabha Sharma
Rick FITCH
Karen GALEN
Dale Wright
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Ard Ip Unlimited Co
Original Assignee
Mallinckrodt Ard Ip Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Ard Ip Unlimited Co filed Critical Mallinckrodt Ard Ip Unlimited Co
Publication of EP3911360A1 publication Critical patent/EP3911360A1/de
Publication of EP3911360A4 publication Critical patent/EP3911360A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/35—Corticotropin [ACTH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP20741802.1A 2019-01-18 2020-01-21 Verfahren zur modulation der corticosteroid-reaktion Pending EP3911360A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962794369P 2019-01-18 2019-01-18
PCT/US2020/014444 WO2020150738A1 (en) 2019-01-18 2020-01-21 Methods of modulating corticosteroid response

Publications (2)

Publication Number Publication Date
EP3911360A1 EP3911360A1 (de) 2021-11-24
EP3911360A4 true EP3911360A4 (de) 2022-09-21

Family

ID=71613659

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20741802.1A Pending EP3911360A4 (de) 2019-01-18 2020-01-21 Verfahren zur modulation der corticosteroid-reaktion

Country Status (3)

Country Link
EP (1) EP3911360A4 (de)
CA (1) CA3125351A1 (de)
WO (1) WO2020150738A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3973978A1 (de) * 2020-09-25 2022-03-30 Mallinckrodt Ard IP Unlimited Company Verfahren zur modulation der corticosteroid-reaktion
WO2023034819A1 (en) * 2021-08-30 2023-03-09 Mallinckrodt Ard Ip Unlimited Company Pre-filled manual injector apparatus
US11975047B1 (en) 2022-10-28 2024-05-07 Ani Pharmaceuticals, Inc. Methods for storing and warming purified corticotropin compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8796416B1 (en) * 2010-10-25 2014-08-05 Questcor Pharmaceuticals, Inc ACTH prophylactic treatment of renal disorders
US10232018B2 (en) * 2013-03-14 2019-03-19 Mallinckrodt Ard Ip Limited ACTH for treatment of acute respiratory distress syndrome

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BENKO A L ET AL: "Repository corticotrophin injection exerts direct acute effects on human B cell gene expression distinct from the actions of glucocorticoids", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, vol. 192, no. 1, 12 January 2018 (2018-01-12), pages 68 - 81, XP071086162, ISSN: 0009-9104, DOI: 10.1111/CEI.13089 *
DUARTE-GARC�A ALI ET AL: "Older Drugs With Limited Trial Evidence: Are They Worth the Expense? The Case of Repository Corticotropin Marketed as H.P. Acthar Gel.", ANNALS OF INTERNAL MEDICINE 04 06 2019, vol. 170, no. 11, 4 June 2019 (2019-06-04), pages 791 - 792, XP009538173, ISSN: 1539-3704 *
See also references of WO2020150738A1 *
WRIGHT D ET AL: "Reduced steroidogenic activity of Repository Corticotropin Injection (RCI) induces a distinct cytokine response following T cell activation in vivo", ANNALS OF THE RHEUMATIC DISEASES 20190601 BMJ PUBLISHING GROUP NLD, vol. 78, no. Supplement 2, 1 June 2019 (2019-06-01), XP009538172, ISSN: 1468-2060 *

Also Published As

Publication number Publication date
CA3125351A1 (en) 2020-07-23
WO2020150738A1 (en) 2020-07-23
EP3911360A1 (de) 2021-11-24

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