EP3920713A4 - Compositions et procédés pour détecter une maladie gastro-intestinale - Google Patents
Compositions et procédés pour détecter une maladie gastro-intestinale Download PDFInfo
- Publication number
- EP3920713A4 EP3920713A4 EP20752596.5A EP20752596A EP3920713A4 EP 3920713 A4 EP3920713 A4 EP 3920713A4 EP 20752596 A EP20752596 A EP 20752596A EP 3920713 A4 EP3920713 A4 EP 3920713A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- gastrointestinal disease
- detecting gastrointestinal
- detecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Husbandry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/267,120 US11493515B2 (en) | 2016-08-04 | 2019-02-04 | Compositions and methods to detect gastrointestinal disease |
| PCT/US2020/016646 WO2020163381A1 (fr) | 2019-02-04 | 2020-02-04 | Compositions et procédés pour détecter une maladie gastro-intestinale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3920713A1 EP3920713A1 (fr) | 2021-12-15 |
| EP3920713A4 true EP3920713A4 (fr) | 2022-11-09 |
Family
ID=83366685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20752596.5A Withdrawn EP3920713A4 (fr) | 2019-02-04 | 2020-02-04 | Compositions et procédés pour détecter une maladie gastro-intestinale |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3920713A4 (fr) |
| CN (2) | CN120102879A (fr) |
| AU (1) | AU2020217717B2 (fr) |
| CA (1) | CA3128826A1 (fr) |
| WO (1) | WO2020163381A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114113624B (zh) * | 2020-08-28 | 2024-08-16 | 香港城市大学深圳研究院 | 利用免疫球蛋白关联蛋白质组开发疾病标志物的方法及装置 |
| US11741686B2 (en) | 2020-12-01 | 2023-08-29 | Raytheon Company | System and method for processing facility image data |
| WO2023141560A2 (fr) * | 2022-01-20 | 2023-07-27 | Synthetic Biologics, Inc. | Phosphatase alcaline destinée à être utilisée en oncologie |
| CN116662798B (zh) * | 2023-04-23 | 2026-02-24 | 迪辅乐生物(上海)有限公司 | 基于肠型分型的微生物组合物、过敏预测模型的构建方法及其模型和应用 |
| WO2025075652A1 (fr) * | 2023-10-06 | 2025-04-10 | DeLorean Artificial Intelligence, Inc. | Système et méthode de gestion de soins médicaux |
| CN120673884B (zh) * | 2025-08-20 | 2025-11-04 | 温州医科大学 | 基于ai的克林霉素磷酸酯加工水解优化方法及系统 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018027179A1 (fr) * | 2016-08-04 | 2018-02-08 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions et méthodes pour détecter une maladie gastro-intestinale |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006026383A2 (fr) * | 2004-08-26 | 2006-03-09 | Strategic Health Decisions, Inc. | Systeme pour optimiser les strategies de traitement au moyen d'un systeme d'evaluation specifique du patient |
| US20140162370A1 (en) * | 2011-06-14 | 2014-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Urine biomarkers for necrotizing enterocolitis and sepsis |
| US10950353B2 (en) * | 2013-09-20 | 2021-03-16 | Georgia Tech Research Corporation | Systems and methods for disease progression modeling |
| BR112017014419A2 (pt) * | 2015-01-09 | 2018-01-16 | S Malo Madhu | diagnose e tratamento de diabetes incipiente |
| CN108061556B (zh) * | 2017-10-18 | 2021-07-09 | 广州傲胜机器人科技有限公司 | 一种基于隐马尔可夫模型的地图匹配方法 |
-
2020
- 2020-02-04 WO PCT/US2020/016646 patent/WO2020163381A1/fr not_active Ceased
- 2020-02-04 CN CN202510261116.9A patent/CN120102879A/zh active Pending
- 2020-02-04 CN CN202080027193.3A patent/CN113645846B/zh active Active
- 2020-02-04 CA CA3128826A patent/CA3128826A1/fr active Pending
- 2020-02-04 EP EP20752596.5A patent/EP3920713A4/fr not_active Withdrawn
- 2020-02-04 AU AU2020217717A patent/AU2020217717B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018027179A1 (fr) * | 2016-08-04 | 2018-02-08 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions et méthodes pour détecter une maladie gastro-intestinale |
| US20190257833A1 (en) * | 2016-08-04 | 2019-08-22 | The Board Of Supervisors Of Louisiana State University And Agricultural And Meo | Compositions and methods to detect gastrointestinal disease |
Non-Patent Citations (4)
| Title |
|---|
| EATON SIMON ET AL: "Current research in necrotizing enterocolitis", EARLY HUMAN DEVELOPMENT, SHANNON, IR, vol. 97, 28 February 2016 (2016-02-28), pages 33 - 39, XP029538630, ISSN: 0378-3782, DOI: 10.1016/J.EARLHUMDEV.2016.01.013 * |
| HEATH MAYA ET AL: "Association of Intestinal Alkaline Phosphatase With Necrotizing Enterocolitis Among Premature Infants", JAMA NETWORK OPEN, vol. 2, no. 11, 1 November 2019 (2019-11-01), pages e1914996, XP055965856, Retrieved from the Internet <URL:https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2754257> DOI: 10.1001/jamanetworkopen.2019.14996 * |
| KAMPANATKOSOL RICHARD ET AL: "The relationship between reticulated platelets, intestinal alkaline phosphatase, and necrotizing enterocolitis", JOURNAL OF PEDIATRIC SURGERY, W. B. SAUNDERS COMPANY, US, vol. 49, no. 2, 21 November 2013 (2013-11-21), pages 273 - 276, XP028612932, ISSN: 0022-3468, DOI: 10.1016/J.JPEDSURG.2013.11.037 * |
| WHITEHOUSE J S ET AL: "The Protective Role of Intestinal Alkaline Phosphatase in Necrotizing Enterocolitis", JOURNAL OF SURGICAL RESEARCH, ACADEMIC PRESS INC., SAN DIEGO, CA, US, vol. 163, no. 1, 1 September 2010 (2010-09-01), pages 79 - 85, XP027212279, ISSN: 0022-4804, [retrieved on 20100521] * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113645846B (zh) | 2025-02-25 |
| CN113645846A (zh) | 2021-11-12 |
| CN120102879A (zh) | 2025-06-06 |
| EP3920713A1 (fr) | 2021-12-15 |
| AU2020217717B2 (en) | 2026-03-12 |
| CA3128826A1 (fr) | 2020-08-13 |
| WO2020163381A1 (fr) | 2020-08-13 |
| AU2020217717A1 (en) | 2021-09-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3920713A4 (fr) | Compositions et procédés pour détecter une maladie gastro-intestinale | |
| EP4139348A4 (fr) | Procédés et compositions pour le traitement d'une inflammation associée à un virus | |
| MA54875A (fr) | Compositions oligonucléotidiques et procédés associés | |
| EP3952914A4 (fr) | Procédés et compositions pour une dégradation de protéine ciblée | |
| EP4045898A4 (fr) | Imagerie de luminescence pour la détection | |
| MA52208A (fr) | Biomarqueurs pour une maladie du greffon contre l'hôte | |
| EP3720458A4 (fr) | Procédés et compositions pour prévenir une infection microbienne | |
| EP3876750A4 (fr) | Procédés de soutien de l'homéostasie gastro-intestinale | |
| EP3678640A4 (fr) | Procédés et compositions pour traiter une maladie cutanée inflammatoire | |
| EP3423128A4 (fr) | Ancrages pyloriques et procédés pour manchons de court-circuit intestinal | |
| KR102223657B9 (ko) | 염증성 장질환 예방 또는 치료용 약학적 조성물 | |
| EP2283119A4 (fr) | Procédés et compositions pour induire une adipogenèse brune | |
| EP3635100A4 (fr) | Compositions et procédés pour exprimer l'otoferline | |
| EP3273944A4 (fr) | Compositions et procédés permettant d'administrer des agents de type biomacromolécule | |
| EP3793562A4 (fr) | Procédés et compositions pour inhiber la dihydroorotate déshydrogénase | |
| EP3446123A4 (fr) | Procédés et compositions pour pronostiquer une naissance prématurée | |
| EP3298151A4 (fr) | Procédés et compositions pour déterminer le ph | |
| EP3803403A4 (fr) | Compositions et procédés d'imagerie | |
| MA44864A (fr) | Trithérapie pour le traitement d'une maladie intestinale inflammatoire | |
| EP2247291A4 (fr) | Procédés et compositions pour traiter une infection intestinale inflammatoire | |
| EP3289064A4 (fr) | Compositions et procédés pour la détection d'allergènes | |
| EP3938783A4 (fr) | Procédés pour maladie cardiovasculaire en cas de polyarthrite rhumatoïde | |
| EP3373950A4 (fr) | Procédés et compositions d'évaluation de spécificités d'anticorps | |
| EP3807319A4 (fr) | Compositions et procédés pour induire une phagocytose | |
| EP3735457A4 (fr) | Compositions et procédés pour produire des mégacaryocytes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20210901 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40064344 Country of ref document: HK |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20221010 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 29/00 20060101ALI20221004BHEP Ipc: A61P 1/00 20060101ALI20221004BHEP Ipc: A23L 33/00 20160101ALI20221004BHEP Ipc: A23L 33/17 20160101ALI20221004BHEP Ipc: A23K 20/195 20160101ALI20221004BHEP Ipc: C12Q 1/42 20060101ALI20221004BHEP Ipc: A61K 9/00 20060101ALI20221004BHEP Ipc: A23C 9/12 20060101AFI20221004BHEP |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
| 17Q | First examination report despatched |
Effective date: 20250124 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20250725 |