EP3946151A1 - Dispositif intraluminal et procédé de résistance à la migration - Google Patents

Dispositif intraluminal et procédé de résistance à la migration

Info

Publication number
EP3946151A1
EP3946151A1 EP20779617.8A EP20779617A EP3946151A1 EP 3946151 A1 EP3946151 A1 EP 3946151A1 EP 20779617 A EP20779617 A EP 20779617A EP 3946151 A1 EP3946151 A1 EP 3946151A1
Authority
EP
European Patent Office
Prior art keywords
tine
sphincter
lumen
muscle
connector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20779617.8A
Other languages
German (de)
English (en)
Other versions
EP3946151A4 (fr
Inventor
Randal Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BFKW LLC
Original Assignee
BFKW LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BFKW LLC filed Critical BFKW LLC
Publication of EP3946151A1 publication Critical patent/EP3946151A1/fr
Publication of EP3946151A4 publication Critical patent/EP3946151A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/848—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/044—Oesophagi or esophagi or gullets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/045—Stomach, intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/828—Means for connecting a plurality of stents allowing flexibility of the whole structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0052—T-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter

Definitions

  • the present invention is directed to a method and structure for resisting migration of an intraluminal device in a lumen and in particular to a lumen that experiences peristalsis.
  • the gastrointestinal (GI) tract is a lumen that includes a number of sphincters or
  • pseudo-sphincters which will be collectively referred to herein as“sphincters”, at various locations.
  • Each sphincter is formed of muscle and is under voluntary and/or involuntary control to close to hold back intraluminal content against the force of peristalsis or open to pass the intraluminal content. Because each sphincter produces at least some narrowing of the lumen, proposals have been made to use the sphincter to resist distal migration of an intraluminal device. However, when the sphincter opens, it is unable to resist distal migration of the intraluminal device which then migrates.
  • the present invention provides a method of resisting migration of a device and an
  • intraluminal device that is both robust and straightforward to deploy without the need for an additional deployment device. It can be used alone or in combination with other fixation techniques.
  • an intraluminal sphincter includes a device having a body with a size and shape of a portion of the lumen.
  • the device further includes at least one tine extending distally from the body.
  • the at least one tine is rigid or semi rigid.
  • the device is deployed in the lumen with the body proximal the sphincter with respect to peristaltic movement of the lumen, with the at least one tine penetrating the muscle of the sphincter.
  • the at least one tine may include at least two tines that are axially spaced around the body with respect to the lumen.
  • the at least one tine may be configured to penetrate the sphincter muscle sufficiently to avoid detachment from the sphincter from the peristalsis of the lumen.
  • the at least one tine may have a length from approximately 0.5 cm to approximately 2.0 cm.
  • the device body may be coupled with another body with a connector, with the other body being positioned distal of the sphincter and the connector passing through the sphincter with the device deployed in the lumen.
  • the device may be deployed by (i) compressing the body and the another body in a deployment device, (ii) positioning the deployment device at least partially distal of the sphincter and deploying the another body from the deployment device distal of the sphincter, (iii) moving the deployment device proximally and deploying the body and the at least one tine proximal the muscle of the sphincter and (iv) further deploying the device from the deployment device wherein the at least one tine subsequently penetrates the sphincter.
  • the connector and/or another device may be sufficiently flexible in order to perform (iii) while maintaining said the other body generally distal to the sphincter.
  • the body may be an esophageal member configured to the size and shape of the distal portion of the esophagus.
  • the other body may be a cardiac member that is configured to the size and shape of a portion of the cardiac portion of the stomach and the connector passes through the esophageal-gastric (EG) sphincter.
  • EG esophageal-gastric
  • the body may be configured to be positioned at the pylorus.
  • the other body may be configured to the size and shape of a portion of the intestine and the connector passes through the pyloric sphincter.
  • the at least one tine penetrates the pyloric sphincter.
  • the body may be configured to be positioned at the throat.
  • the other body may be configured to the size and shape of a portion of the esophagus and the connector passes through the upper esophageal sphincter.
  • the at least one tine penetrates the upper esophageal sphincter.
  • the body may be configured to be proximal the ileocecal valve, the other body may be configured to the size and shape of a portion of the large colon and the connector passes through the ileocecal valve.
  • the at least one tine penetrates the sphincter of the ileocecal valve.
  • the at least one tine may be directed distally and outwardly but more distally than
  • the at least one tine may have a length of between approximately 0.5 cm and 2.0 cm.
  • the angle between each tine and the central axis of the body may be between 5 degrees and approximately 45 degrees.
  • An enlarged tip may be provided on the at least one tine to resist catching on a deployment device or other surface.
  • the at least one tine may be configured to be retained entirely within the lumen and not penetrate the lumen.
  • An intraluminal device that is adapted to be deployed in a lumen that experiences
  • peristaltic waves and has muscle defining an intraluminal sphincter includes a body having a size and shape of a portion of the lumen proximal of the sphincter and at least one tine extending distally from a distal portion of the body.
  • the at least one tine is rigid or semi rigid.
  • the at least one tine extends distally from the body with respect to peristaltic movement of the lumen and is adapted to penetrate the muscle of the sphincter when the body is deployed in the lumen proximal to the sphincter.
  • the at least one tine may be at least two tines that are axially spaced around with
  • the at least one tine may have a length of at least a wavelength of a peristaltic wave of the lumen.
  • the body may be coupled with another body using a connector.
  • the other body has a size and shape to be deployed downstream of the sphincter and the connector being configured to pass through the sphincter.
  • the body may be an esophageal member that is configured to the size and shape of the distal portion of the esophagus and the other body a cardiac member that is configured to the size and shape of a portion of the cardiac portion of the stomach.
  • the connector is adapted to pass through the esophageal-gastric (EG) sphincter and the at least one tine adapted to penetrate the EG sphincter.
  • the body may be configured to the size and shape of a portion of the pylorus and the other body configured to the size and shape of a portion of the intestine.
  • the connector is adapted to pass through the pyloric sphincter and the at least one tine adapted to penetrate the pyloric sphincter.
  • the body may be configured to be positioned proximal the upper esophageal sphincter and the other body configured to the size and shape of a portion of the esophagus.
  • the connector is adapted to pass through the upper esophageal sphincter and the at least one tine adapted to penetrate the upper esophageal sphincter.
  • the body may be configured to be positioned proximal the ileocecal valve and the other body configured to the size and shape of a portion of the large intestine.
  • the connector is adapted to pass through the ileocecal valve and the at least one tine adapted to penetrate the sphincter of the ileocecal valve.
  • the at least one tine may be directed distally and outwardly but more distally than
  • An intraluminal device that is adapted to be deployed in a lumen that experiences
  • peristaltic waves and has muscle defining an intraluminal sphincter includes an esophageal member having a size and shape of a distal portion of the esophagus and at least one tine extending distally from a distal portion of the esophageal member.
  • the at least one tine is rigid or semi-rigid.
  • the at least one tine is adapted to penetrate the muscle of the EG sphincter when the esophageal member is deployed in the esophagus proximal to the gastro-esophageal sphincter.
  • a cardiac member is coupled with said esophageal member with a connector.
  • the connector is configured to cause the cardiac member to apply stress to the cardiac portion of the stomach when the connector passes through the gastro-esophageal sphincter and the cardiac member is in the stomach.
  • the at least one tine may be configured to penetrate the sphincter sufficiently to avoid separating from the sphincter by peristaltic effect on the device.
  • the at least one tine may have a length of between approximately 0.5 cm and approximately 2.0 cm.
  • the angle between each tine and the central axis of the esophageal member may be between approximately 5 degrees and approximately 45 degrees outwardly.
  • a method of resisting migration of a device in a lumen having muscle defining an
  • intraluminal sphincter includes the device having a body with a size and shape of a portion of the lumen.
  • the device further includes at least one tine extending outwardly and distally from the body.
  • the at least one tine is rigid or semi rigid.
  • the device is deployed in the lumen with the body proximal the sphincter with respect to peristaltic movement of the lumen with the at least one tine penetrating the muscle of the sphincter.
  • the device is explanted by moving the at least one tine to not extend outwardly from the body.
  • the device may include a removal ring at a proximal end portion of the body and a retraction ring at a distal end portion of the body that is connected with the removal ring.
  • Proximal force applied to the removal ring causes the retraction ring to move the at least one tine inwardly.
  • the traction ring may move the at least one tine inwardly by a (i) reducing a diameter of the distal end portion of the body (ii), pulling inwardly on the at least one tine, and/or (iii) retracting the at least one tine into a pouch.
  • FIG. 2 is a view of the intraluminal device in FIG. 1 deployed to the GI tract of a
  • ESP esophageal-gastric sphincter
  • FIG. 4 is a sectional view taken along the lines IV-IV in FIG 3;
  • FIG. 5 is a side elevation of an alternative embodiment of an intraluminal device
  • FIG. 9 is a sectional view taken along the lines IX-IX in FIG. 8.
  • Intraluminal device 10 has a body 14 having a size and shape of a portion of the lumen proximal of the sphincter with respect to peristaltic movement of the lumen and a through opening 15 that allows movement of intraluminal content through the body.
  • the through opening may be a central passage through the body or a shape of the body that allows intraluminal content to bypass the body.
  • Intraluminal device 10 further includes at least one tine 16.
  • the at least one tine 16 extends distally from a distal portion of body 14 and is rigid or semi rigid. In this manner, with body 14 deployed in the lumen proximal the sphincter, the at least one tine 16 penetrates the muscle that defines the sphincter as peristalsis causes distal motion of the body thrusting the at least one tine distally. The penetration of the at least one tine in the sphincter is sufficient to resist action of peristalsis of lumen 12 separating the at least one tine from the sphincter. In this manner distal migration of body 14 is resisted even as the sphincter opens and closes.
  • each tine 16 may be sufficient to resist distal migration of body 14, at least two tines 16 that are axially spaced around body 14 with respect to lumen 12 enhances and more evenly distributes the forces resisting peristalsis.
  • each tine 16 is between approximately 0.5 cm and approximately 2.0 cm. In this manner, even with proximate/distal movement of body 14 in response to peristalsis of lumen 12, any
  • tine(s) 16 may be of different lengths to provide a variety of engagements with the sphincter.
  • device 110 body 114 is coupled with another body 18 with a connector 20.
  • intraluminal device 110 deployed at lumen 12 with body 114 proximal the sphincter and tine(s) 16 penetrating the EG sphincter
  • another body 18 is distal of the sphincter and connector 20 connecting body 114 with another body 18 passing through the EG sphincter.
  • Connector 20 is configured to not substantially interfere with operation of the sphincter while passing through the sphincter.
  • FIG 4 illustrates a possible arrangement of a plurality of tines 16 disposed angularly around the distal end of body 114. As can be seen, two tines 16 angle radially away from each connector 20 and two tines angle radially away from each other offset from the connectors. Other arrangements are possible.
  • Intraluminal device 110 may be deployed with a deployment device of the type
  • Deployment begins by compressing body 114 and another body 18 and positioning them in the deployment device along with connector 20.
  • the deployment device is deployed in the lumen 12 at least partially distal of the EG sphincter using techniques disclosed in the‘326 patent.
  • Another body 18 is deployed from the deployment device distal of the EG sphincter.
  • the deployment device is then pulled proximally and body 114 and at least one tine 16 is deployed from the deployment device in a position that is proximal the muscle of the EG sphincter.
  • distal movement of the body will result in the at least one tine 116 penetrating the muscle of the EG sphincter.
  • Intraluminal device 110 may be explan ted with an endoscopic grasper or hook pulling proximally on a removal ring 30.
  • ring 30 is made of a suture or other material weaving between proximal ends 32 of the support mesh of body 114 (FIG. 7). This distributes the proximal force evenly around the perimeter of body 114 and pulls the wall inward from the esophagus thus reducing any tendency to injure the esophagus.
  • One or more force transfer sutures 34 transfers the movement of removal ring 30 to a retraction ring 36.
  • Retraction ring 36 retracts tines 16 inwardly in order to reduce any scratching of the tine tips along the esophagus as body 114 is removed.
  • Retraction ring 36 functions by applying an inward force on a distal end of body 114, by applying an inward force directly on the tines 16 or by retracting the tines into pockets provided in body 114. Other methods will be apparent to the skilled artisan.
  • body 114 is an esophageal member 22 configured to the size and shape of the distal portion of the esophagus and another body 18 is a cardiac member 24 that is configured to the size and shape of a portion of the cardiac portion of the stomach as illustrated in FIG 3.
  • Connector 20 passes through the esophageal-gastric (EG) sphincter.
  • EG esophageal-gastric
  • cardiac member 24 applies pressure to the cardiac portion of the stomach at least part of the time via connector 20 being under tension.
  • connector 20 and/or cardiac member 24 may be sufficiently flexible in order to accommodate temporary further spacing between the esophageal member and the cardiac member while maintaining position of the cardiac member 24 generally distal of the EG sphincter. This may be accomplished by connector 20 being elastic and/or by cardiac member 24 being flexible. In that manner, the connector and/or cardiac member can flex to allow tine(s) 16 to engage the EG sphincter then relax sufficiently to place pressure on the cardiac portion of the stomach
  • a device 210 has a body 214 that is configured to be positioned at the pyloric and another body 118 that is configured to the size and shape of a portion of the small or large intestine.
  • a connector 120 passes through the pyloric sphincter in a manner that does not interfere with operation of the sphincter.
  • Tines 16 extending distally from body 214 penetrate the pyloric sphincter (PS) in a manner that resists distal migration of device 210.
  • PS pyloric sphincter
  • a device 310 has a body 314 that is configured to be positioned proximate the upper esophageal sphincter and another body 218 that is configured to the size and shape of a portion of the esophagus.
  • a connector 220 passes through the upper esophageal sphincter in a manner that does not interfere with operation of the sphincter.
  • Tines 16 extending from body 314 penetrate the upper esophageal sphincter sufficiently to resist distal migration of device 310.
  • a device embodying the invention may use the sphincter of the ileocecal valve in order to position another body in the large colon in a manner that will be apparent to the skilled artisan.
  • Tine(s) 16 can be made of nitinol wire, stainless steel, titanium, carbon fiber, or the like, covered with a biocompatible material such as a silicone coating. This makes the tine(s) stiff yet flexible. Each tine is directed generally distally but with an outward slant. This ensures that the tine engages the sphincter. Each tine is directed more distally than outwardly so that shear forces on the tine are minimal. Also this minimizes possibility of the tine penetrating the wall of lumen 12.
  • the angle between each tine and the central axis of body 314 may be between approximately 5 degrees and approximately 45 degrees but a greater or lesser amount may be used such as between approximately 5 degrees and approximately 30 degrees or approximately 10 degrees.
  • An enlarged tip 26 of tine(s) 16 may be provided to resist catching on a deployment device or other surface. Although two tines 16 are shown, one on each side of body 414, more than two tines may be used. A plurality of additional distally directed tines may be deployed, each between one of the ones shown and body 418.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Prostheses (AREA)

Abstract

La présente invention concerne un dispositif intraluminal et un procédé de résistance à la migration d'un dispositif dans une lumière, la lumière ayant un muscle définissant un sphincter intraluminal comprend un dispositif ayant un corps ayant une taille et une forme d'une partie de la lumière. Le dispositif comprend en outre au moins une dent s'étendant de manière distale à partir du corps. La ou les dents sont rigides ou semi-rigides. Le dispositif est déployé dans la lumière avec le corps à proximité du sphincter par rapport au mouvement péristaltique de la lumière et avec la ou les dents pénétrant dans le muscle du sphincter pour résister à une migration distale.
EP20779617.8A 2019-03-25 2020-03-24 Dispositif intraluminal et procédé de résistance à la migration Withdrawn EP3946151A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962823259P 2019-03-25 2019-03-25
PCT/IB2020/052765 WO2020194189A1 (fr) 2019-03-25 2020-03-24 Dispositif intraluminal et procédé de résistance à la migration

Publications (2)

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Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5020584A (en) * 1988-11-10 1991-06-04 Lanxide Technology Company, Lp Method for forming metal matrix composites having variable filler loadings and products produced thereby
US7678068B2 (en) * 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
ATE422858T1 (de) * 2003-03-28 2009-03-15 Gi Dynamics Inc Vorrichtungen gegen fettleibigkeit
US8142513B2 (en) * 2006-08-23 2012-03-27 Svip 2 Llc Devices and methods for altering eating behavior
US8529431B2 (en) * 2007-02-14 2013-09-10 Bfkw, Llc Bariatric device and method
WO2008101048A2 (fr) * 2007-02-14 2008-08-21 Bfkw, Llc Dispositif et procédé bariatrique
DE202010017584U1 (de) * 2009-05-08 2012-02-29 Université Libre de Bruxelles Gastrointestinale Vorrichtung
US20100305590A1 (en) * 2009-05-29 2010-12-02 Gi Dynamics, Inc. Transpyloric Anchoring
US10111663B2 (en) * 2011-02-18 2018-10-30 Ancora Heart, Inc. Implant retrieval device
JP6162690B2 (ja) * 2011-05-20 2017-07-12 ビーエフケイダブリュ・リミテッド・ライアビリティ・カンパニーＢｆｋｗ， Ｌｌｃ 高めた抗遊走性を備える管腔内デバイス及び管腔内の方法
JP6730991B2 (ja) * 2014-12-29 2020-07-29 ビーエフケイダブリュ・エルエルシーＢｆｋｗ， Ｌｌｃ 腔内デバイス
KR20210005038A (ko) * 2018-03-30 2021-01-13 메타모딕스, 인코포레이티드 위장 보철물 고정 및 제한을 위한 시스템 및 방법
CN108938163B (zh) * 2018-04-12 2023-12-26 杭州糖吉医疗科技有限公司 胃导流器及其释放方法

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EP3946151A4 (fr) 2022-12-07
CN113795221A (zh) 2021-12-14

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