EP4018181A4 - Verfahren zur modifizierung einer flüssigen probe mit einem analyten, um die sers-signalintensität des analyten zu erhöhen, sowie eine sonde zur fernerfassung eines analyten unter verwendung von sers - Google Patents

Verfahren zur modifizierung einer flüssigen probe mit einem analyten, um die sers-signalintensität des analyten zu erhöhen, sowie eine sonde zur fernerfassung eines analyten unter verwendung von sers Download PDF

Info

Publication number: EP4018181A4
Authority: EP; European Patent Office
Prior art keywords: analyte; sers; modifying; probe; increase
Prior art date: 2019-08-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP20854885.9A

Other languages

English (en)

French (fr)

Other versions

EP4018181C0 (de

EP4018181B1 (de

EP4018181A1 (de

Inventor

Xu Zhang

Albert Collins NGANOU ASSONKENG

Andrew James CARRIER

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cape Breton University

Original Assignee

Cape Breton University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2019-08-22

Filing date

2020-08-21

Publication date

2023-08-02

2020-08-21 Application filed by Cape Breton University filed Critical Cape Breton University

2022-06-29 Publication of EP4018181A1 publication Critical patent/EP4018181A1/de

2023-08-02 Publication of EP4018181A4 publication Critical patent/EP4018181A4/de

2025-12-31 Application granted granted Critical

2025-12-31 Publication of EP4018181C0 publication Critical patent/EP4018181C0/de

2025-12-31 Publication of EP4018181B1 publication Critical patent/EP4018181B1/de

Status Active legal-status Critical Current

2040-08-21 Anticipated expiration legal-status Critical

Links

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4412—Scattering spectrometry
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

Physics & Mathematics (AREA)
Spectroscopy & Molecular Physics (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Engineering & Computer Science (AREA)
Nanotechnology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Pathology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Crystallography & Structural Chemistry (AREA)
Molecular Biology (AREA)
Composite Materials (AREA)
Condensed Matter Physics & Semiconductors (AREA)
Materials Engineering (AREA)
Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Investigating Or Analysing Materials By Optical Means (AREA)

EP20854885.9A 2019-08-22 2020-08-21 Verfahren zur modifizierung einer flüssigen probe mit einem analyten, um die sers-signalintensität des analyten zu erhöhen, sowie eine sonde zur fernerfassung eines analyten unter verwendung von sers Active EP4018181B1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201962890216P	2019-08-22	2019-08-22
PCT/CA2020/051143 WO2021030914A1 (en)	2019-08-22	2020-08-21	Methods of modifying a liquid sample containing an analyte so as to increase sers signal intensity of the analyte, as well as a probe for remote sensing of an analyte using sers

Publications (4)

Publication Number	Publication Date
EP4018181A1 EP4018181A1 (de)	2022-06-29
EP4018181A4 true EP4018181A4 (de)	2023-08-02
EP4018181C0 EP4018181C0 (de)	2025-12-31
EP4018181B1 EP4018181B1 (de)	2025-12-31

Family

ID=74659839

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP20854885.9A Active EP4018181B1 (de)	2019-08-22	2020-08-21	Verfahren zur modifizierung einer flüssigen probe mit einem analyten, um die sers-signalintensität des analyten zu erhöhen, sowie eine sonde zur fernerfassung eines analyten unter verwendung von sers

Country Status (7)

Country	Link
US (1)	US12560481B2 (de)
EP (1)	EP4018181B1 (de)
KR (1)	KR102993558B1 (de)
CN (1)	CN114599959B (de)
AU (1)	AU2020332709B9 (de)
CA (1)	CA3151843A1 (de)
WO (1)	WO2021030914A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN117589687B (zh) *	2024-01-18	2024-04-09	成都艾立本科技有限公司	基于空气包裹液体的光学腔容器及用途及光谱检测方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080024762A1 (en) *	2006-07-31	2008-01-31	Applied Materials, Inc.	Raman spectroscopy as integrated chemical metrology
WO2013185167A1 (en) *	2012-06-13	2013-12-19	Monash University	Metallic nanoparticle treated cellulosic substrate as a sers biodiagnostic platform
CN108982465A (zh) *	2018-06-06	2018-12-11	上海应用技术大学	酒中二氧化硫高通量sers在线检测方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2008032719A (ja) *	2006-07-31	2008-02-14	Applied Materials Inc	集積化学計測としてのラマン分光法
CA2681523C (en)	2007-03-20	2017-11-28	Kristin Weidemaier	Assays using surface-enhanced raman spectroscopy (sers)-active particles
WO2010033267A2 (en) *	2008-05-06	2010-03-25	University Of Georgia Research Foundation, Inc.	Structures, methods of making structures, multi-well array surface enhanced raman spectroscopy (sers) chips, methods of making, and methods of use
CA2799786A1 (en)	2010-06-09	2011-12-15	Semprus Biosciences Corp.	Non-fouling, anti-microbial, anti-thrombogenic graft compositions
SG187921A1 (en) *	2010-08-24	2013-03-28	Agency Science Tech & Res	Substrate for optical sensing by surface enhanced raman spectroscopy (sers) and methods for forming the same
US9272126B2 (en)	2011-04-29	2016-03-01	The Board Of Trustees Of The University Of Illinois	Photonic biosensors incorporated into tubing, methods of manufacture and instruments for analyzing the biosensors
US20130045877A1 (en) *	2011-08-19	2013-02-21	Agency For Science, Technology And Research	Methods to form substrates for optical sensing by surface enhanced raman spectroscopy (sers) and substrates formed by the methods
US11237159B2 (en) *	2016-03-23	2022-02-01	Agency For Science, Technology And Research	Surface enhanced Raman spectroscopy (SERS) microfluidics biosensor for detecting single and/or multiple analytes
CN107365254B (zh)	2016-05-12	2021-06-04	北京大学	一种聚合物微球在拉曼检测中的应用
CN108247036B (zh) *	2018-01-15	2019-09-13	南京大学	一种金属纳米多孔结构及其制备方法和应用

2020
- 2020-08-21 CA CA3151843A patent/CA3151843A1/en active Pending
- 2020-08-21 AU AU2020332709A patent/AU2020332709B9/en active Active
- 2020-08-21 EP EP20854885.9A patent/EP4018181B1/de active Active
- 2020-08-21 KR KR1020227009350A patent/KR102993558B1/ko active Active
- 2020-08-21 US US17/753,113 patent/US12560481B2/en active Active
- 2020-08-21 WO PCT/CA2020/051143 patent/WO2021030914A1/en not_active Ceased
- 2020-08-21 CN CN202080073674.8A patent/CN114599959B/zh active Active

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080024762A1 (en) *	2006-07-31	2008-01-31	Applied Materials, Inc.	Raman spectroscopy as integrated chemical metrology
WO2013185167A1 (en) *	2012-06-13	2013-12-19	Monash University	Metallic nanoparticle treated cellulosic substrate as a sers biodiagnostic platform
CN108982465A (zh) *	2018-06-06	2018-12-11	上海应用技术大学	酒中二氧化硫高通量sers在线检测方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021030914A1 *

Also Published As

Publication number	Publication date
CN114599959B (zh)	2026-02-06
AU2020332709A1 (en)	2022-03-24
EP4018181C0 (de)	2025-12-31
KR102993558B1 (ko)	2026-07-21
WO2021030914A1 (en)	2021-02-25
AU2020332709B2 (en)	2025-10-16
EP4018181B1 (de)	2025-12-31
KR20220054818A (ko)	2022-05-03
US20220334063A1 (en)	2022-10-20
EP4018181A1 (de)	2022-06-29
CA3151843A1 (en)	2021-02-25
US12560481B2 (en)	2026-02-24
CN114599959A (zh)	2022-06-07
AU2020332709B9 (en)	2025-10-30

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