EP4045022C0 - Zusammensetzung zur verhinderung und behandlung von tauopathien - Google Patents

Zusammensetzung zur verhinderung und behandlung von tauopathien

Info

Publication number
EP4045022C0
EP4045022C0 EP20780933.6A EP20780933A EP4045022C0 EP 4045022 C0 EP4045022 C0 EP 4045022C0 EP 20780933 A EP20780933 A EP 20780933A EP 4045022 C0 EP4045022 C0 EP 4045022C0
Authority
EP
European Patent Office
Prior art keywords
tauopathies
prevention
treatment
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP20780933.6A
Other languages
English (en)
French (fr)
Other versions
EP4045022A2 (de
EP4045022B1 (de
Inventor
De Fonseca Fernando Rodriguez
Galera Juan Antonio Navarro
Llano Elena Baixeras
Del Olmo Juan Manuel Decara
Vera Dina Medina
Gambero Antonio Jesús López
Perez Juan Suarez
Merino Carlos Sanjuan
Del Valle Cristina Rosell
Morón Francisco Javier Pavón
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Malaga
Servicio Andaluz de Salud
Original Assignee
Universidad de Malaga
Servicio Andaluz de Salud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Malaga, Servicio Andaluz de Salud filed Critical Universidad de Malaga
Priority to EP25184120.1A priority Critical patent/EP4599696A3/de
Publication of EP4045022A2 publication Critical patent/EP4045022A2/de
Application granted granted Critical
Publication of EP4045022B1 publication Critical patent/EP4045022B1/de
Publication of EP4045022C0 publication Critical patent/EP4045022C0/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
EP20780933.6A 2019-09-09 2020-09-09 Zusammensetzung zur verhinderung und behandlung von tauopathien Active EP4045022B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP25184120.1A EP4599696A3 (de) 2019-09-09 2020-09-09 Zusammensetzung und verfahren zur verbesserung oder förderung einer gesunden metabolischen alterung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19382778.9A EP3789018A1 (de) 2019-09-09 2019-09-09 Zusammensetzung und verfahren zur steigerung oder förderung der sekretion von ghrelin zur förderung einer gesunden metabolischen alterung
PCT/EP2020/075180 WO2021048195A2 (en) 2019-09-09 2020-09-09 Composition and methods for enhancing or promoting a healthy metabolic aging

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP25184120.1A Division EP4599696A3 (de) 2019-09-09 2020-09-09 Zusammensetzung und verfahren zur verbesserung oder förderung einer gesunden metabolischen alterung

Publications (3)

Publication Number Publication Date
EP4045022A2 EP4045022A2 (de) 2022-08-24
EP4045022B1 EP4045022B1 (de) 2025-07-09
EP4045022C0 true EP4045022C0 (de) 2025-07-09

Family

ID=67902476

Family Applications (3)

Application Number Title Priority Date Filing Date
EP19382778.9A Withdrawn EP3789018A1 (de) 2019-09-09 2019-09-09 Zusammensetzung und verfahren zur steigerung oder förderung der sekretion von ghrelin zur förderung einer gesunden metabolischen alterung
EP20780933.6A Active EP4045022B1 (de) 2019-09-09 2020-09-09 Zusammensetzung zur verhinderung und behandlung von tauopathien
EP25184120.1A Pending EP4599696A3 (de) 2019-09-09 2020-09-09 Zusammensetzung und verfahren zur verbesserung oder förderung einer gesunden metabolischen alterung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP19382778.9A Withdrawn EP3789018A1 (de) 2019-09-09 2019-09-09 Zusammensetzung und verfahren zur steigerung oder förderung der sekretion von ghrelin zur förderung einer gesunden metabolischen alterung

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP25184120.1A Pending EP4599696A3 (de) 2019-09-09 2020-09-09 Zusammensetzung und verfahren zur verbesserung oder förderung einer gesunden metabolischen alterung

Country Status (8)

Country Link
US (1) US20220313620A1 (de)
EP (3) EP3789018A1 (de)
JP (2) JP2022547641A (de)
CN (2) CN120938973A (de)
CA (1) CA3153663A1 (de)
ES (1) ES3041902T3 (de)
PL (1) PL4045022T3 (de)
WO (1) WO2021048195A2 (de)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550166A (en) * 1995-03-17 1996-08-27 Ostlund; Richard E. Pinitol and derivatives thereof for the treatment of metabolic disorders
US7521481B2 (en) * 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
US20060004096A1 (en) * 2004-05-28 2006-01-05 Joseph Larner Method of Treating Endothelial Dysfunction, Oxidative Stress and Related Diseases
JP2008510494A (ja) * 2004-08-25 2008-04-10 マルチ・フォーミュレーションズ・リミテッド 骨格筋における異化過程の失活及びタンパク質合成のための組成物並びに方法
US8193250B2 (en) * 2004-10-22 2012-06-05 Mount Sinai School Of Medicine Compositions and methods for treating alzheimer's disease and related disorders and promoting a healthy nervous system
WO2008025116A1 (en) * 2006-08-31 2008-03-06 New Nitro Formulations Ltd. Composition and method for enhancing or promoting the activity of insulin, enhancing skeletal muscle growth, reducing skeletal muscle loss, and increasing the energy supply to skeletal muscle
KR100844363B1 (ko) * 2007-09-05 2008-07-07 충남대학교산학협력단 D-피니톨을 유효성분으로 포함하는 골 대사성 질환의 예방 또는 치료용 조성물
CN101612142A (zh) * 2008-06-25 2009-12-30 广州威尔曼新药开发中心有限公司 肌醇衍生物或其盐在制药中的用途
ITFI20110252A1 (it) * 2011-11-22 2013-05-23 Lo Li Pharma Srl Composizione farmaceutica comprendente myo-inositolo e d-chiro-inositolo.
CA2941650A1 (en) * 2014-03-05 2015-09-11 Humanetics Corporation Predicting and reducing cognitive decline based on gsk-3 levels
KR101671502B1 (ko) * 2015-07-13 2016-11-02 주식회사 디와이내츄럴 피니톨, d-카이로-이노시톨, 또는 이들의 유사 화합물을 유효성분으로 포함하는 여성 갱년기 증상의 개선, 예방, 또는 치료용 조성물
JP6838146B2 (ja) * 2016-10-06 2021-03-03 ディーワイ ナチュラル カンパニー リミテッド ピニトール、d−カイロ−イノシトール、又はこれらの類似化合物を有効成分として含む、女性の更年期症状の改善、予防、又は治療用の組成物

Also Published As

Publication number Publication date
WO2021048195A9 (en) 2022-04-21
JP2025169353A (ja) 2025-11-12
CN120938973A (zh) 2025-11-14
JP2022547641A (ja) 2022-11-14
PL4045022T3 (pl) 2025-11-17
EP4045022A2 (de) 2022-08-24
CN114641281A (zh) 2022-06-17
CA3153663A1 (en) 2021-03-18
EP4045022B1 (de) 2025-07-09
US20220313620A1 (en) 2022-10-06
EP4599696A2 (de) 2025-08-13
WO2021048195A3 (en) 2021-04-29
EP3789018A1 (de) 2021-03-10
ES3041902T3 (en) 2025-11-17
EP4599696A3 (de) 2026-01-07
WO2021048195A2 (en) 2021-03-18

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