EP4070107A4 - Système et procédé d'échange de peptides à base de molécules de classe ii du cmh - Google Patents

Système et procédé d'échange de peptides à base de molécules de classe ii du cmh Download PDF

Info

Publication number
EP4070107A4
EP4070107A4 EP20896724.0A EP20896724A EP4070107A4 EP 4070107 A4 EP4070107 A4 EP 4070107A4 EP 20896724 A EP20896724 A EP 20896724A EP 4070107 A4 EP4070107 A4 EP 4070107A4
Authority
EP
European Patent Office
Prior art keywords
molecule
mhc class
exchange system
based peptide
peptide exchange
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20896724.0A
Other languages
German (de)
English (en)
Other versions
EP4070107A2 (fr
Inventor
Marc DELCOMMENNE
Yuri POLUEKTOV
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MBL International Corp
Original Assignee
MBL International Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MBL International Corp filed Critical MBL International Corp
Publication of EP4070107A2 publication Critical patent/EP4070107A2/fr
Publication of EP4070107A4 publication Critical patent/EP4070107A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
EP20896724.0A 2019-12-06 2020-12-04 Système et procédé d'échange de peptides à base de molécules de classe ii du cmh Withdrawn EP4070107A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962944998P 2019-12-06 2019-12-06
PCT/US2020/063393 WO2021113700A2 (fr) 2019-12-06 2020-12-04 Système et procédé d'échange de peptides à base de molécules de classe ii du cmh

Publications (2)

Publication Number Publication Date
EP4070107A2 EP4070107A2 (fr) 2022-10-12
EP4070107A4 true EP4070107A4 (fr) 2024-02-14

Family

ID=76222031

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20896724.0A Withdrawn EP4070107A4 (fr) 2019-12-06 2020-12-04 Système et procédé d'échange de peptides à base de molécules de classe ii du cmh

Country Status (2)

Country Link
EP (1) EP4070107A4 (fr)
WO (1) WO2021113700A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017197244A1 (fr) * 2016-05-13 2017-11-16 Mbl International Corp. Système et procédé d'échange de peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007524583A (ja) * 2003-03-07 2007-08-30 ロンドン・ヘルス・サイエンシズ・センター・リサーチ・インコーポレーテッド 自己免疫異常に関わるｈｌａ−ｄｒｍｈｃクラスｉｉ分子に関するペプチド
US11069427B2 (en) * 2013-06-10 2021-07-20 Iogenetics, Llc Mathematical processes for determination of peptidase cleavage

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017197244A1 (fr) * 2016-05-13 2017-11-16 Mbl International Corp. Système et procédé d'échange de peptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DELCOMMENNE MARC C ET AL: "The QuickSwitch Quant HLA-A*02:01 Tetramer Kit can be used for determining the biological activity of a cancer vaccine.", THE JOURNAL OF IMMUNOLOGY, vol. 198, no. 1_Supplement, 1 May 2017 (2017-05-01), US, pages 79.27 - 79.27, XP093108131, ISSN: 0022-1767, Retrieved from the Internet <URL:https://journals.aai.org/jimmunol/article/198/1_Supplement/79.27/55247/The-QuickSwitch-Quant-HLA-A-02-01-Tetramer-Kit-can> DOI: 10.4049/jimmunol.198.Supp.79.27 *
POLUEKTOV YURI ET AL: "Assessment of SARS-CoV-2 specific CD4(+) and CD8 (+) T cell responses using MHC class I and II tetramers", VACCINE, vol. 39, no. 15, 1 April 2021 (2021-04-01), AMSTERDAM, NL, pages 2110 - 2116, XP093005957, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2021.03.008 *
YIN LIUSONG ET AL: "Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization", CURRENT PROTOCOLS IN IMMUNOLOGY, vol. 106, no. 1, 1 August 2015 (2015-08-01), XP093108096, ISSN: 1934-3671, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151172/pdf/nihms-619710.pdf> DOI: 10.1002/0471142735.im0510s106 *

Also Published As

Publication number Publication date
WO2021113700A3 (fr) 2021-07-29
EP4070107A2 (fr) 2022-10-12
WO2021113700A2 (fr) 2021-06-10

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