EP4161549A4 - Procédé d'obtention d'une solution purifiée d'alcaloïde psychoactif - Google Patents

Procédé d'obtention d'une solution purifiée d'alcaloïde psychoactif Download PDF

Info

Publication number
EP4161549A4
EP4161549A4 EP21881426.7A EP21881426A EP4161549A4 EP 4161549 A4 EP4161549 A4 EP 4161549A4 EP 21881426 A EP21881426 A EP 21881426A EP 4161549 A4 EP4161549 A4 EP 4161549A4
Authority
EP
European Patent Office
Prior art keywords
purified
obtaining
alkaloid solution
psychoactive
psychoactive alkaloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21881426.7A
Other languages
German (de)
English (en)
Other versions
EP4161549A1 (fr
Inventor
Ryan Moss
Benjamin Lightburn
Lisa Ranken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psilo Scientific Ltd
Original Assignee
Psilo Scientific Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA3097246A external-priority patent/CA3097246C/fr
Priority claimed from PCT/CA2021/050813 external-priority patent/WO2021253116A1/fr
Application filed by Psilo Scientific Ltd filed Critical Psilo Scientific Ltd
Publication of EP4161549A1 publication Critical patent/EP4161549A1/fr
Publication of EP4161549A4 publication Critical patent/EP4161549A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/078—Psilocybe
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP21881426.7A 2020-10-23 2021-10-23 Procédé d'obtention d'une solution purifiée d'alcaloïde psychoactif Pending EP4161549A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA3097246A CA3097246C (fr) 2020-10-23 2020-10-23 Processus d`obtention d`une solution alcaloide psychoactive purifiee
PCT/CA2021/050813 WO2021253116A1 (fr) 2020-06-17 2021-06-14 Compositions comprenant des composés psychoactifs à partir d'organismes psychoactifs
PCT/CA2021/051495 WO2022082320A1 (fr) 2020-10-23 2021-10-23 Procédé d'obtention d'une solution purifiée d'alcaloïde psychoactif

Publications (2)

Publication Number Publication Date
EP4161549A1 EP4161549A1 (fr) 2023-04-12
EP4161549A4 true EP4161549A4 (fr) 2023-11-29

Family

ID=81291112

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21881426.7A Pending EP4161549A4 (fr) 2020-10-23 2021-10-23 Procédé d'obtention d'une solution purifiée d'alcaloïde psychoactif

Country Status (4)

Country Link
EP (1) EP4161549A4 (fr)
BR (1) BR112022025782A2 (fr)
MX (1) MX2023004350A (fr)
WO (1) WO2022082320A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220370413A1 (en) 2021-03-06 2022-11-24 Mind Medicine, Inc. Formulations of psilocin that have enhanced stability
CN119656653B (zh) * 2025-02-18 2025-06-13 浙江工业大学 氰胺废渣炭在莲生物碱萃取中的应用、一种固相萃取吸附剂及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101491647A (zh) * 2007-04-18 2009-07-29 北京和润创新医药科技发展有限公司 一种从中药麦角提取液中分离麦角总生物碱的方法
CA3123908A1 (fr) * 2020-06-17 2020-10-07 Psilo Scientific Ltd. Extraction a l'ethanol de composes psychoactifs de champignons psilocybines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4169535A1 (fr) * 2019-04-26 2023-04-26 The University of North Carolina at Chapel Hill Procédés et compositions de double liaison glycane de vecteurs de vaa2.5

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101491647A (zh) * 2007-04-18 2009-07-29 北京和润创新医药科技发展有限公司 一种从中药麦角提取液中分离麦角总生物碱的方法
CA3123908A1 (fr) * 2020-06-17 2020-10-07 Psilo Scientific Ltd. Extraction a l'ethanol de composes psychoactifs de champignons psilocybines

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200961, Derwent World Patents Index; AN 2009-M36108, XP002810227 *
FAKHARI ALI REZA ET AL: "Optimized ultrasound-assisted extractionprocedure for the analysis of opium alkaloids in papaver plants by cyclodextrin-modified capillary electrophoresis", JOURNAL OF SEPARATION SCIENCE, WILEY, DE, vol. 33, no. 14, 30 June 2010 (2010-06-30), pages 2153 - 2159, XP009548440, ISSN: 1615-9306, DOI: 10.1002/JSSC.201000135 *
PELLEGRINI MANUELA ET AL: "Magic truffles or Philosopher's stones: a legal way to sell psilocybin?", vol. 5, no. 3, 28 February 2013 (2013-02-28), pages 182 - 185, XP009547892, ISSN: 1942-7611, Retrieved from the Internet <URL:https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fdta.1400> [retrieved on 20120809], DOI: 10.1002/DTA.1400 *
See also references of WO2022082320A1 *

Also Published As

Publication number Publication date
BR112022025782A2 (pt) 2024-01-30
MX2023004350A (es) 2023-09-12
WO2022082320A1 (fr) 2022-04-28
EP4161549A1 (fr) 2023-04-12

Similar Documents

Publication Publication Date Title
EP4312871C0 (fr) Procédé de formation d&#39;un aligneur dentaire
EP3971158A4 (fr) Procédé de préparation d&#39;un composé de cannabidiol
EP3642416C0 (fr) Procédé de fabrication d&#39;une bande fibreuse
EP4126862C0 (fr) Procédé de préparation d&#39;un composé inhibiteur de cot
EP4185845C0 (fr) Surveillance de l&#39;etat physique d&#39;un rail
EP4431145A4 (fr) Procédé de fabrication de microaiguille
EP3827967C0 (fr) Procédé de fabrication additive d&#39;une préforme
EP4161549A4 (fr) Procédé d&#39;obtention d&#39;une solution purifiée d&#39;alcaloïde psychoactif
EP3848361C0 (fr) Procédé de production de composé tétracyclique
EP4259219A4 (fr) Procédé de fabrication de tissu régénératif
EP4077798C0 (fr) Procédé de fabrication d&#39;une nappe fibreuse
EP4434976A4 (fr) Procédé de production d&#39;un composé de 2-hétéroarylpyridine
EP4396195A4 (fr) Procédé d&#39;obtention d&#39;une composition d&#39;anticorps purifiée
EP4453698A4 (fr) Procédé de production d&#39;un signal de rétroaction bio-précis
EP3808261C0 (fr) Procédé de production d&#39;une bioélectrode
EP4075451C0 (fr) Procédé de fabrication de bioélectrode
EP4434977A4 (fr) Procédé de production d&#39;un composé de 2-hétéroarylpyridine
EP4434970A4 (fr) Procédé de production d&#39;un composé d&#39;imidazole halogénovinylique
EP4184528A4 (fr) Procédé de production de solution 225ac
EP4417582A4 (fr) Procédé de purification d&#39;une solution cible de traitement
EP4341637C0 (fr) Procédé de fabrication d&#39;un composant de tête explosive
EP3608309A4 (fr) Procédé de purification de composé trifluorométhylpyridine
EP4293002A4 (fr) Procédé de production d&#39;un composé d&#39;alcénylphosphore
EP4426533A4 (fr) Procédé de fabrication additive modulaire
EP4456681A4 (fr) Procédé de fabrication d&#39;une carte de circuit imprimé

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20230106

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

RAP3 Party data changed (applicant data changed or rights of an application transferred)

Owner name: PSILO SCIENTIFIC LTD

A4 Supplementary search report drawn up and despatched

Effective date: 20231102

RIC1 Information provided on ipc code assigned before grant

Ipc: B01D 15/42 20060101ALI20231025BHEP

Ipc: B01D 15/36 20060101ALI20231025BHEP

Ipc: B01D 15/08 20060101ALI20231025BHEP

Ipc: B01D 11/02 20060101ALI20231025BHEP

Ipc: A61K 36/07 20060101ALI20231025BHEP

Ipc: A61K 36/48 20060101AFI20231025BHEP

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)