EP4170032A4 - Procédé de détermination d'une maladie provoquée par un dysfonctionnement synaptique ou une maladie accompagnée d'un dysfonctionnement synaptique - Google Patents
Procédé de détermination d'une maladie provoquée par un dysfonctionnement synaptique ou une maladie accompagnée d'un dysfonctionnement synaptique Download PDFInfo
- Publication number
- EP4170032A4 EP4170032A4 EP21826587.4A EP21826587A EP4170032A4 EP 4170032 A4 EP4170032 A4 EP 4170032A4 EP 21826587 A EP21826587 A EP 21826587A EP 4170032 A4 EP4170032 A4 EP 4170032A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- synaptic dysfunction
- accompanied
- determining
- disease caused
- synaptic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003976 synaptic dysfunction Effects 0.000 title 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020106421A JP7244931B2 (ja) | 2020-06-19 | 2020-06-19 | シナプス機能不全に起因する、又はシナプス機能不全を付随する疾病の判定方法 |
| PCT/JP2021/023135 WO2021256550A1 (fr) | 2020-06-19 | 2021-06-18 | Procédé de détermination d'une maladie provoquée par un dysfonctionnement synaptique ou une maladie accompagnée d'un dysfonctionnement synaptique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4170032A1 EP4170032A1 (fr) | 2023-04-26 |
| EP4170032A4 true EP4170032A4 (fr) | 2024-12-18 |
Family
ID=79244367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP21826587.4A Pending EP4170032A4 (fr) | 2020-06-19 | 2021-06-18 | Procédé de détermination d'une maladie provoquée par un dysfonctionnement synaptique ou une maladie accompagnée d'un dysfonctionnement synaptique |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230349925A1 (fr) |
| EP (1) | EP4170032A4 (fr) |
| JP (3) | JP7244931B2 (fr) |
| CN (1) | CN115702352A (fr) |
| WO (1) | WO2021256550A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2024122459A1 (fr) * | 2022-12-05 | 2024-06-13 | ||
| WO2025177848A1 (fr) * | 2024-02-22 | 2025-08-28 | アルメッド株式会社 | Imadp dérivé de drébrine, procédé de mesure d'imadp et kit de mesure d'imadp |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003180361A (ja) * | 2001-12-13 | 2003-07-02 | Japan Science & Technology Corp | ｓ−ドレブリンＡ |
| US20040180048A1 (en) * | 2002-07-12 | 2004-09-16 | The Johns Hopkins University | Neuronal and retinal gene expression patterns |
| CN109490527A (zh) * | 2018-11-08 | 2019-03-19 | 温州医科大学 | Dbn1蛋白在制备神经变性疾病诊断药物中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4568463B2 (ja) | 2001-11-05 | 2010-10-27 | 独立行政法人科学技術振興機構 | ドレブリンａ発現抑制動物神経細胞及び非ヒトモデル動物 |
| JP4550530B2 (ja) | 2004-09-03 | 2010-09-22 | 独立行政法人科学技術振興機構 | シナプス成熟障害モデル動物 |
| JP2016040540A (ja) | 2014-08-13 | 2016-03-24 | 国立大学法人群馬大学 | ドレブリンａ及びドレブリンｅの特異的定量法 |
| WO2016205730A1 (fr) * | 2015-06-18 | 2016-12-22 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Protéines citrullinées et leurs produits de dégradation en tant que biomarqueurs de tbi |
| JP7111494B2 (ja) | 2018-04-05 | 2022-08-02 | グローリー株式会社 | 光検出センサ、光検出装置、シート類処理装置および光検出方法 |
| JP7324994B2 (ja) | 2018-05-08 | 2023-08-14 | アルメッド株式会社 | ドレブリンに特異的に結合するペプチド、及びそのペプチドを用いたドレブリンの検出方法 |
| JP7536240B2 (ja) | 2019-03-13 | 2024-08-20 | 国立大学法人群馬大学 | Ｎｍｄａ受容体阻害活性のハイスループット評価方法 |
| JP7416399B2 (ja) | 2019-10-08 | 2024-01-17 | アルメッド株式会社 | アルツハイマー病モデル非ヒト動物及びその製造方法 |
-
2020
- 2020-06-19 JP JP2020106421A patent/JP7244931B2/ja active Active
-
2021
- 2021-06-18 WO PCT/JP2021/023135 patent/WO2021256550A1/fr not_active Ceased
- 2021-06-18 CN CN202180043301.0A patent/CN115702352A/zh active Pending
- 2021-06-18 US US18/002,332 patent/US20230349925A1/en active Pending
- 2021-06-18 EP EP21826587.4A patent/EP4170032A4/fr active Pending
-
2023
- 2023-03-03 JP JP2023032921A patent/JP7620340B2/ja active Active
-
2024
- 2024-12-27 JP JP2024231531A patent/JP2025060925A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003180361A (ja) * | 2001-12-13 | 2003-07-02 | Japan Science & Technology Corp | ｓ−ドレブリンＡ |
| US20040180048A1 (en) * | 2002-07-12 | 2004-09-16 | The Johns Hopkins University | Neuronal and retinal gene expression patterns |
| CN109490527A (zh) * | 2018-11-08 | 2019-03-19 | 温州医科大学 | Dbn1蛋白在制备神经变性疾病诊断药物中的应用 |
Non-Patent Citations (2)
| Title |
|---|
| JULIKA PITSCH ET AL: "Drebrin Autoantibodies in Patients with Seizures and Suspected Encephalitis", ANNALS OF NEUROLOGY, JOHN WILEY AND SONS, BOSTON , US, vol. 87, no. 6, 10 April 2020 (2020-04-10), pages 869 - 884, XP071645181, ISSN: 0364-5134, DOI: 10.1002/ANA.25720 * |
| See also references of WO2021256550A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025060925A (ja) | 2025-04-10 |
| JP2022001838A (ja) | 2022-01-06 |
| US20230349925A1 (en) | 2023-11-02 |
| EP4170032A1 (fr) | 2023-04-26 |
| JP7244931B2 (ja) | 2023-03-23 |
| JP7620340B2 (ja) | 2025-01-23 |
| WO2021256550A1 (fr) | 2021-12-23 |
| CN115702352A (zh) | 2023-02-14 |
| JP2023075214A (ja) | 2023-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20230113 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20241115 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/68 20060101ALI20241111BHEP Ipc: G01N 33/53 20060101ALI20241111BHEP Ipc: G01N 33/50 20060101ALI20241111BHEP Ipc: G01N 33/15 20060101ALI20241111BHEP Ipc: C12N 15/12 20060101AFI20241111BHEP |