EP4178545A4 - Immunogene zusammensetzung zur bildung eines impfstoffs und verfahren zu deren herstellung - Google Patents

Immunogene zusammensetzung zur bildung eines impfstoffs und verfahren zu deren herstellung Download PDF

Info

Publication number
EP4178545A4
EP4178545A4 EP21838378.4A EP21838378A EP4178545A4 EP 4178545 A4 EP4178545 A4 EP 4178545A4 EP 21838378 A EP21838378 A EP 21838378A EP 4178545 A4 EP4178545 A4 EP 4178545A4
Authority
EP
European Patent Office
Prior art keywords
vaccine
production
forming
immunogenic composition
immunogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21838378.4A
Other languages
English (en)
French (fr)
Other versions
EP4178545A2 (de
Inventor
Mitra Mosharraf
Aryo SORAYYA
Rajiv Nayar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Engimata Inc
Original Assignee
Engimata Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/925,438 external-priority patent/US11278617B2/en
Priority claimed from US17/204,511 external-priority patent/US11559577B2/en
Application filed by Engimata Inc filed Critical Engimata Inc
Publication of EP4178545A2 publication Critical patent/EP4178545A2/de
Publication of EP4178545A4 publication Critical patent/EP4178545A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
EP21838378.4A 2020-07-10 2021-07-12 Immunogene zusammensetzung zur bildung eines impfstoffs und verfahren zu deren herstellung Pending EP4178545A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/925,438 US11278617B2 (en) 2020-03-31 2020-07-10 Immunogenic composition forming a SARS-CoV-2 vaccine, and a method for its manufacture
US17/204,511 US11559577B2 (en) 2020-03-31 2021-03-17 Immunogenic composition forming a vaccine, and a method for its manufacture
PCT/US2021/041245 WO2022011332A2 (en) 2020-07-10 2021-07-12 Immunogenic composition forming a vaccine, and a method for its manufacture

Publications (2)

Publication Number Publication Date
EP4178545A2 EP4178545A2 (de) 2023-05-17
EP4178545A4 true EP4178545A4 (de) 2024-08-07

Family

ID=79553742

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21838378.4A Pending EP4178545A4 (de) 2020-07-10 2021-07-12 Immunogene zusammensetzung zur bildung eines impfstoffs und verfahren zu deren herstellung

Country Status (2)

Country Link
EP (1) EP4178545A4 (de)
WO (1) WO2022011332A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118490818A (zh) 2020-04-22 2024-08-16 生物技术欧洲股份公司 冠状病毒疫苗
US12186387B2 (en) 2021-11-29 2025-01-07 BioNTech SE Coronavirus vaccine
CN116808194A (zh) * 2022-03-22 2023-09-29 中国科学院化学研究所 一种纳米疫苗载体、纳米疫苗及其制备方法和应用
US11878055B1 (en) 2022-06-26 2024-01-23 BioNTech SE Coronavirus vaccine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019191780A9 (en) * 2018-03-30 2020-06-18 Arcturus Therapeutics, Inc. Lipid particles for nucleic acid delivery
WO2021183563A1 (en) * 2020-03-09 2021-09-16 Arcturus Therapeutics, Inc. Coronavirus vaccine compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1938835A1 (de) * 2006-12-29 2008-07-02 Pevion Biotech AG Nichtspezifische immunostimulierende Wirkstoffe
US9603799B2 (en) * 2013-03-15 2017-03-28 Htd Biosystems Inc. Liposomal vaccine adjuvants and methods of making and using same
KR20160091350A (ko) * 2013-11-29 2016-08-02 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019191780A9 (en) * 2018-03-30 2020-06-18 Arcturus Therapeutics, Inc. Lipid particles for nucleic acid delivery
WO2021183563A1 (en) * 2020-03-09 2021-09-16 Arcturus Therapeutics, Inc. Coronavirus vaccine compositions and methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TREVOR R. F. SMITH ET AL: "Immunogenicity of a DNA vaccine candidate for COVID-19", NATURE COMMUNICATIONS, vol. 11, no. 1, 20 May 2020 (2020-05-20), XP055767550, DOI: 10.1038/s41467-020-16505-0 *

Also Published As

Publication number Publication date
EP4178545A2 (de) 2023-05-17
WO2022011332A2 (en) 2022-01-13
WO2022011332A3 (en) 2022-02-17

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