EP4178568A4 - Compositions et procédés pour le traitement de l'apnée obstructive du sommeil (aos) - Google Patents

Compositions et procédés pour le traitement de l'apnée obstructive du sommeil (aos) Download PDF

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Publication number
EP4178568A4
EP4178568A4 EP21837113.6A EP21837113A EP4178568A4 EP 4178568 A4 EP4178568 A4 EP 4178568A4 EP 21837113 A EP21837113 A EP 21837113A EP 4178568 A4 EP4178568 A4 EP 4178568A4
Authority
EP
European Patent Office
Prior art keywords
osa
compositions
treatment
methods
sleep apnea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21837113.6A
Other languages
German (de)
English (en)
Other versions
EP4178568A1 (fr
Inventor
Mark Robert BLEACKLEY
Sudhanshu Agarwal
Joel Bradley LATHAM
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incannex Healthcare Ltd
Original Assignee
Incannex Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2020902368A external-priority patent/AU2020902368A0/en
Application filed by Incannex Healthcare Ltd filed Critical Incannex Healthcare Ltd
Publication of EP4178568A1 publication Critical patent/EP4178568A1/fr
Publication of EP4178568A4 publication Critical patent/EP4178568A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP21837113.6A 2020-07-09 2021-07-09 Compositions et procédés pour le traitement de l'apnée obstructive du sommeil (aos) Pending EP4178568A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2020902368A AU2020902368A0 (en) 2020-07-09 A method of treatment
PCT/AU2021/050734 WO2022006636A1 (fr) 2020-07-09 2021-07-09 Compositions et procédés pour le traitement de l'apnée obstructive du sommeil (aos)

Publications (2)

Publication Number Publication Date
EP4178568A1 EP4178568A1 (fr) 2023-05-17
EP4178568A4 true EP4178568A4 (fr) 2024-10-16

Family

ID=79553355

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21837113.6A Pending EP4178568A4 (fr) 2020-07-09 2021-07-09 Compositions et procédés pour le traitement de l'apnée obstructive du sommeil (aos)

Country Status (8)

Country Link
US (1) US20230310364A1 (fr)
EP (1) EP4178568A4 (fr)
JP (1) JP7796718B2 (fr)
AU (1) AU2021306424A1 (fr)
CA (1) CA3182528A1 (fr)
CO (1) CO2023000118A2 (fr)
IL (1) IL299212A (fr)
WO (1) WO2022006636A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025520386A (ja) * 2022-06-21 2025-07-03 アプニメッド，インコーポレイテッド（デラウェア） カンナビノイドおよびカルボニックアンヒドラーゼ阻害剤の組合せを用いた睡眠時無呼吸を治療する方法
EP4626410A1 (fr) * 2022-11-29 2025-10-08 Incannex Healthcare Limited Méthode de traitement de l'apnée obstructive du sommeil (osa)
WO2025107039A1 (fr) * 2023-11-23 2025-05-30 Incannex Healthcare Limited Composition comprenant du tétrahydrocannabinol et de l'acétazolamide dans une capsule combinée à dose fixe
WO2025191322A1 (fr) * 2024-03-11 2025-09-18 Mousavi Mirzaei Seyed Mohammad Composition thérapeutique pour atténuer les symptômes de l'apnée obstructive du sommeil

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2620672T3 (es) * 2008-01-09 2017-06-29 Charleston Laboratories, Inc. Comprimidos de doble capa que comprenden oxicodona y prometazina
WO2019071302A1 (fr) * 2017-10-09 2019-04-18 The University Of Sydney Méthodes et compositions pour le traitement ou la prévention des crises d'épilepsie
US20220000833A1 (en) * 2018-01-29 2022-01-06 Therapix Biosciences Ltd. Compositions and methods for treating obstructive sleep apnea
WO2019180706A1 (fr) * 2018-03-19 2019-09-26 Bol Pharma Ltd. Méthodes et compositions pour le traitement de l'épilepsie et des troubles associés
US20240189328A1 (en) * 2021-04-16 2024-06-13 Apnimed, Inc. (Delaware) Combination of norepinephrine reuptake inhibitor and a cannabinoid for use in treating sleep apnea

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DAVID W CARLEY ET AL: "Pharmacotherapy of Apnea by Cannabimimetic Enhancement, the PACE Clinical Trial: Effects of Dronabinol in Obstructive Sleep Apnea", SLEEP, vol. 41, no. 1, 7 November 2017 (2017-11-07), US, XP055627158, ISSN: 0161-8105, DOI: 10.1093/sleep/zsx184 *
EDWARDS BRADLEY A. ET AL: "Acetazolamide Attenuates the Ventilatory Response to Arousal in Patients with Obstructive Sleep Apnea", SLEEP, vol. 36, no. 2, 1 February 2013 (2013-02-01), US, pages 281 - 285, XP093188886, ISSN: 0161-8105, DOI: 10.5665/sleep.2390 *
See also references of WO2022006636A1 *

Also Published As

Publication number Publication date
EP4178568A1 (fr) 2023-05-17
US20230310364A1 (en) 2023-10-05
CO2023000118A2 (es) 2023-04-17
WO2022006636A1 (fr) 2022-01-13
CA3182528A1 (fr) 2022-01-13
IL299212A (en) 2023-02-01
AU2021306424A1 (en) 2023-01-19
JP2023533289A (ja) 2023-08-02
JP7796718B2 (ja) 2026-01-09

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Ipc: A61K 45/06 20060101ALI20240912BHEP

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