EP4188331A4 - Lentille de contact chargée à surface limite destinée à une administration - Google Patents

Lentille de contact chargée à surface limite destinée à une administration

Info

Publication number
EP4188331A4
EP4188331A4 EP21904586.1A EP21904586A EP4188331A4 EP 4188331 A4 EP4188331 A4 EP 4188331A4 EP 21904586 A EP21904586 A EP 21904586A EP 4188331 A4 EP4188331 A4 EP 4188331A4
Authority
EP
European Patent Office
Prior art keywords
distribution
contact lens
charged limit
charged
limit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21904586.1A
Other languages
German (de)
English (en)
Other versions
EP4188331A1 (fr
Inventor
Arthur Jing-Min Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lynthera Corp
Original Assignee
Lynthera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lynthera Corp filed Critical Lynthera Corp
Publication of EP4188331A1 publication Critical patent/EP4188331A1/fr
Publication of EP4188331A4 publication Critical patent/EP4188331A4/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
EP21904586.1A 2020-12-09 2021-12-07 Lentille de contact chargée à surface limite destinée à une administration Pending EP4188331A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063123237P 2020-12-09 2020-12-09
PCT/US2021/072779 WO2022126100A1 (fr) 2020-12-09 2021-12-07 Lentille de contact chargée à surface limite destinée à une administration

Publications (2)

Publication Number Publication Date
EP4188331A1 EP4188331A1 (fr) 2023-06-07
EP4188331A4 true EP4188331A4 (fr) 2025-10-29

Family

ID=81974028

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21904586.1A Pending EP4188331A4 (fr) 2020-12-09 2021-12-07 Lentille de contact chargée à surface limite destinée à une administration

Country Status (5)

Country Link
US (1) US11504323B2 (fr)
EP (1) EP4188331A4 (fr)
JP (1) JP2023533421A (fr)
CN (1) CN115379826B (fr)
WO (1) WO2022126100A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023523398A (ja) * 2020-04-15 2023-06-05 リンセラ コーポレイション 多孔性ナノコンポジット医療用インプラント装置
WO2024015959A1 (fr) 2022-07-15 2024-01-18 Praful Doshi Lentilles de contact avec médicaments et leurs procédés de fabrication et d'utilisation faisant intervenir des stabilisants de composants labiles tels que des médicaments
GB2629236B (en) * 2024-01-24 2025-07-16 Coopervision Int Ltd Contact Lens Formulation and Contact Lens

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902007B1 (fr) * 2006-06-09 2012-01-13 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s) ainsi que leurs applications notamment therapeutiques
US9248928B2 (en) * 2012-12-21 2016-02-02 Coopervision International Holding Company, Lp Methods of manufacturing contact lenses for delivery of beneficial agents
JP2019530556A (ja) * 2016-09-30 2019-10-24 リンセラ コーポレイション 二重領域眼球用デバイスによる高精度薬物送達
JP2022540583A (ja) * 2019-07-17 2022-09-16 テオン セラピューティクス,インク. アデノシンa2a受容体アンタゴニスト及びその使用
JP2023523398A (ja) 2020-04-15 2023-06-05 リンセラ コーポレイション 多孔性ナノコンポジット医療用インプラント装置

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BENGANI LOKENDRAKUMAR C. ET AL: "Extended delivery of an anionic drug by contact lens loaded with a cationic surfactant", BIOMATERIALS, vol. 34, no. 11, 1 April 2013 (2013-04-01), AMSTERDAM, NL, pages 2814 - 2821, XP055813811, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2012.12.027 *
CESAR TORRES-LUNA ET AL: "Extended delivery of non-steroidal anti-inflammatory drugs through contact lenses loaded with Vitamin E and cationic surfactants", CONTACT LENS AND ANTERIOR EYE, vol. 42, no. 5, 1 October 2019 (2019-10-01), GB, pages 546 - 552, XP055686052, ISSN: 1367-0484, DOI: 10.1016/j.clae.2019.04.011 *
See also references of WO2022126100A1 *
TORRES-LUNA CESAR ET AL: "Effect of Carbon Chain Length, Ionic Strength, and pH on the In Vitro Release Kinetics of Cationic Drugs from Fatty-Acid-Loaded Contact Lenses", PHARMACEUTICS, vol. 13, no. 7, 10 July 2021 (2021-07-10), Switzerland, pages 1060, XP093313745, ISSN: 1999-4923, DOI: 10.3390/pharmaceutics13071060 *
TORRES-LUNA CESAR ET AL: "Extended delivery of cationic drugs from contact lenses loaded with unsaturated fatty acids", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 155, 1 October 2020 (2020-10-01), NL, pages 1 - 11, XP055884167, ISSN: 0939-6411, Retrieved from the Internet <URL:https://www.sciencedirect.com/science/article/pii/S0939641120302368/pdfft?md5=c203f09e748313eef25cdf077d3ba745&pid=1-s2.0-S0939641120302368-main.pdf> DOI: 10.1016/j.ejpb.2020.07.033 *

Also Published As

Publication number Publication date
US11504323B2 (en) 2022-11-22
JP2023533421A (ja) 2023-08-03
CN115379826B (zh) 2023-07-21
CN115379826A (zh) 2022-11-22
US20220192975A1 (en) 2022-06-23
WO2022126100A1 (fr) 2022-06-16
EP4188331A1 (fr) 2023-06-07

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A4 Supplementary search report drawn up and despatched

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 9/00 20060101AFI20250924BHEP

Ipc: A61L 27/54 20060101ALI20250924BHEP

Ipc: A61F 9/00 20060101ALI20250924BHEP

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