EP4271381A4 - Méthodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obèses - Google Patents

Méthodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obèses Download PDF

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Publication number
EP4271381A4
EP4271381A4 EP21916093.4A EP21916093A EP4271381A4 EP 4271381 A4 EP4271381 A4 EP 4271381A4 EP 21916093 A EP21916093 A EP 21916093A EP 4271381 A4 EP4271381 A4 EP 4271381A4
Authority
EP
European Patent Office
Prior art keywords
brexpiprazole
methods
psychiatric disorders
obese patients
treating psychiatric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP21916093.4A
Other languages
German (de)
English (en)
Other versions
EP4271381A1 (fr
Inventor
Sundar Srinivasan
Christina Chow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lake O'hara LLC
Original Assignee
Lake O'hara LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/139,627 external-priority patent/US11229644B1/en
Priority claimed from US17/139,690 external-priority patent/US20220202810A1/en
Application filed by Lake O'hara LLC filed Critical Lake O'hara LLC
Publication of EP4271381A1 publication Critical patent/EP4271381A1/fr
Publication of EP4271381A4 publication Critical patent/EP4271381A4/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP21916093.4A 2020-12-31 2021-02-03 Méthodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obèses Withdrawn EP4271381A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17/139,627 US11229644B1 (en) 2020-12-31 2020-12-31 Methods of treating psychiatric disorders in obese patients with brexpiprazole
US17/139,690 US20220202810A1 (en) 2020-12-31 2020-12-31 Methods of treating psychiatric disorders in obese patients with brexpiprazole
PCT/US2021/016329 WO2022146462A1 (fr) 2020-12-31 2021-02-03 Méthodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obèses

Publications (2)

Publication Number Publication Date
EP4271381A1 EP4271381A1 (fr) 2023-11-08
EP4271381A4 true EP4271381A4 (fr) 2024-12-11

Family

ID=82259620

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21916093.4A Withdrawn EP4271381A4 (fr) 2020-12-31 2021-02-03 Méthodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obèses

Country Status (5)

Country Link
EP (1) EP4271381A4 (fr)
JP (1) JP2024502431A (fr)
AU (1) AU2021412785A1 (fr)
CA (1) CA3201123A1 (fr)
WO (1) WO2022146462A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11229644B1 (en) 2020-12-31 2022-01-25 Lake O'hara Llc Methods of treating psychiatric disorders in obese patients with brexpiprazole
WO2023141634A2 (fr) * 2022-01-24 2023-07-27 Lake O'hara Llc Méthodes de traitement à base de brexpiprazole chez des patients obèses atteints de troubles psychiatriques

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0618879D0 (en) * 2006-09-26 2006-11-01 Zysis Ltd Pharmaceutical compositions
KR102169426B1 (ko) * 2013-02-27 2020-10-23 모찌다 세이야쿠 가부시끼가이샤 신규 피라졸 유도체
CA2904387C (fr) * 2013-03-15 2021-12-07 Melinta Therapeutics, Inc. Procedes de traitement d'infections chez des patients atteints de surpoids et d'obesite utilisant d'antibiotiques
JP2020520380A (ja) * 2017-05-16 2020-07-09 ボウ リバー エルエルシー 処置法
EP3761983A1 (fr) * 2018-03-05 2021-01-13 Alkermes Pharma Ireland Limited Stratégie de dosage d'aripiprazole
US12357598B2 (en) * 2018-12-21 2025-07-15 The Regents Of The University Of California Treatment of neurodevelopmental disorders

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CITROME L: "Brexpiprazole for schizophrenia and as adjunct for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antipsychotic - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?", INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, MEDICON INTERNATIONAL, ESHER, GB, vol. 69, no. 9, 6 August 2015 (2015-08-06), pages 978 - 997, XP072061985, ISSN: 1368-5031, DOI: 10.1111/IJCP.12714 *
ORSOLINI LAURA ET AL: "Up-to-date expert opinion on the safety of recently developed antipsychotics", EXPERT OPINION ON DRUG SAFETY, vol. 19, no. 8, 2 August 2020 (2020-08-02), GB, pages 981 - 998, XP093098068, ISSN: 1474-0338, DOI: 10.1080/14740338.2020.1795126 *
See also references of WO2022146462A1 *

Also Published As

Publication number Publication date
JP2024502431A (ja) 2024-01-19
CA3201123A1 (fr) 2022-07-07
EP4271381A1 (fr) 2023-11-08
AU2021412785A1 (en) 2023-06-22
WO2022146462A1 (fr) 2022-07-07

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