EP4352266A4 - Krebsdetektionsverfahren, kit und system - Google Patents

Krebsdetektionsverfahren, kit und system

Info

Publication number
EP4352266A4
EP4352266A4 EP22820856.7A EP22820856A EP4352266A4 EP 4352266 A4 EP4352266 A4 EP 4352266A4 EP 22820856 A EP22820856 A EP 22820856A EP 4352266 A4 EP4352266 A4 EP 4352266A4
Authority
EP
European Patent Office
Prior art keywords
kit
detection method
cancer detection
cancer
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22820856.7A
Other languages
English (en)
French (fr)
Other versions
EP4352266A2 (de
Inventor
Andrew Zhang
Hai Hu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mironcol Inc
Original Assignee
Mironcol Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mironcol Inc filed Critical Mironcol Inc
Publication of EP4352266A2 publication Critical patent/EP4352266A2/de
Publication of EP4352266A4 publication Critical patent/EP4352266A4/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Evolutionary Biology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Databases & Information Systems (AREA)
  • Immunology (AREA)
  • Data Mining & Analysis (AREA)
  • Biomedical Technology (AREA)
  • Primary Health Care (AREA)
  • Software Systems (AREA)
  • Hospice & Palliative Care (AREA)
  • Evolutionary Computation (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP22820856.7A 2021-06-09 2022-06-07 Krebsdetektionsverfahren, kit und system Pending EP4352266A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163208506P 2021-06-09 2021-06-09
PCT/US2022/032423 WO2022261039A2 (en) 2021-06-09 2022-06-07 Cancer detection method, kit, and system

Publications (2)

Publication Number Publication Date
EP4352266A2 EP4352266A2 (de) 2024-04-17
EP4352266A4 true EP4352266A4 (de) 2025-12-10

Family

ID=84426392

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22820856.7A Pending EP4352266A4 (de) 2021-06-09 2022-06-07 Krebsdetektionsverfahren, kit und system

Country Status (6)

Country Link
EP (1) EP4352266A4 (de)
JP (1) JP2024523848A (de)
CN (1) CN117500941A (de)
AU (1) AU2022289858A1 (de)
CA (1) CA3221494A1 (de)
WO (1) WO2022261039A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110799648B (zh) * 2017-06-29 2024-03-22 东丽株式会社 用于检测肺癌的试剂盒、装置和方法
CA3098105A1 (en) * 2018-04-25 2019-10-31 Toray Industries, Inc. Kit, device, and method for detecting bladder cancer
CN117802235B (zh) * 2022-09-30 2025-08-19 上海思路迪生物医学科技有限公司 血液胞外囊泡miRNA在卵巢癌诊断中的应用
KR20250159710A (ko) * 2023-03-13 2025-11-11 미론콜 다이아그노스틱스 리미티드 암 진단 모델의 개발 방법 및 암 검출 방법 개발에서의 이의 용도
WO2025128926A1 (en) * 2023-12-13 2025-06-19 Amazon Technologies, Inc. Methods of identifying and treating individuals with elevated cancer risk
WO2026015599A1 (en) * 2024-07-10 2026-01-15 Mironcol Diagnostics, Ltd. Machine learning-based diagnostic classifiers for predicting cancer tissue of origin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019183620A1 (en) * 2018-03-23 2019-09-26 The Regents Of The University Of California Non-invasive classification of benign and malignant melanocytic lesions using microrna profiling
US20200140956A1 (en) * 2017-04-28 2020-05-07 Toray Industries, Inc. Kit, device, and method for detecting ovarian tumor
JP2020188683A (ja) * 2019-05-17 2020-11-26 株式会社Aldock 胃癌または食道癌を検出するための癌マーカー

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9495515B1 (en) * 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US20120041274A1 (en) * 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
US20150011414A1 (en) * 2012-01-16 2015-01-08 Herlev Hospital Microrna for diagnosis of pancreatic cancer and/or prognosis of patients with pancreatic cancer by blood samples
US9708667B2 (en) * 2014-05-13 2017-07-18 Rosetta Genomics, Ltd. MiRNA expression signature in the classification of thyroid tumors
EP3191602A1 (de) * 2014-09-09 2017-07-19 Istituto Europeo di Oncologia S.r.l. Verfahren zur erkennung von lungenkrebs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200140956A1 (en) * 2017-04-28 2020-05-07 Toray Industries, Inc. Kit, device, and method for detecting ovarian tumor
WO2019183620A1 (en) * 2018-03-23 2019-09-26 The Regents Of The University Of California Non-invasive classification of benign and malignant melanocytic lesions using microrna profiling
JP2020188683A (ja) * 2019-05-17 2020-11-26 株式会社Aldock 胃癌または食道癌を検出するための癌マーカー

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RITCHIE MATTHEW E. ET AL: "limma powers differential expression analyses for RNA-sequencing and microarray studies", NUCLEIC ACIDS RESEARCH, vol. 43, no. 7, 20 January 2015 (2015-01-20), GB, pages e47 - e47, XP093214494, ISSN: 0305-1048, DOI: 10.1093/nar/gkv007 *

Also Published As

Publication number Publication date
JP2024523848A (ja) 2024-07-02
CA3221494A1 (en) 2022-12-15
WO2022261039A3 (en) 2023-01-19
EP4352266A2 (de) 2024-04-17
WO2022261039A2 (en) 2022-12-15
AU2022289858A1 (en) 2024-01-04
CN117500941A (zh) 2024-02-02

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RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/6886 20180101AFI20250811BHEP

Ipc: C12Q 1/6813 20180101ALI20250811BHEP

Ipc: C12Q 1/6837 20180101ALI20250811BHEP

Ipc: C12Q 1/6869 20180101ALI20250811BHEP

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Ipc: C12M 1/34 20060101ALI20250811BHEP

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Ipc: C12N 15/113 20100101ALI20250811BHEP

Ipc: G16B 20/00 20190101ALI20250811BHEP

Ipc: G16B 25/10 20190101ALI20250811BHEP

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A4 Supplementary search report drawn up and despatched

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RIC1 Information provided on ipc code assigned before grant

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Ipc: C12Q 1/6813 20180101ALI20251104BHEP

Ipc: C12Q 1/6837 20180101ALI20251104BHEP

Ipc: C12Q 1/6869 20180101ALI20251104BHEP

Ipc: B01L 7/00 20060101ALI20251104BHEP

Ipc: C12M 1/34 20060101ALI20251104BHEP

Ipc: C12N 15/09 20060101ALI20251104BHEP

Ipc: C12N 15/113 20100101ALI20251104BHEP

Ipc: G16B 20/00 20190101ALI20251104BHEP

Ipc: G16B 25/10 20190101ALI20251104BHEP

Ipc: G16B 40/00 20190101ALI20251104BHEP

Ipc: G16H 50/20 20180101ALI20251104BHEP