EP4426732A4 - An porphyromonas gingivalis bindende antigenbindende moleküle - Google Patents

An porphyromonas gingivalis bindende antigenbindende moleküle

Info

Publication number
EP4426732A4
EP4426732A4 EP22889542.1A EP22889542A EP4426732A4 EP 4426732 A4 EP4426732 A4 EP 4426732A4 EP 22889542 A EP22889542 A EP 22889542A EP 4426732 A4 EP4426732 A4 EP 4426732A4
Authority
EP
European Patent Office
Prior art keywords
binding
antigen
porphyromonas gingivalis
binding molecules
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22889542.1A
Other languages
English (en)
French (fr)
Other versions
EP4426732A2 (de
Inventor
Peter L Nara
Daniel L Sindelar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
K Bio Investment LLC
K Bio Invest LLC
Original Assignee
K Bio Investment LLC
K Bio Invest LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2021/057758 external-priority patent/WO2022098661A1/en
Priority claimed from US18/051,456 external-priority patent/US20230365662A1/en
Application filed by K Bio Investment LLC, K Bio Invest LLC filed Critical K Bio Investment LLC
Publication of EP4426732A2 publication Critical patent/EP4426732A2/de
Publication of EP4426732A4 publication Critical patent/EP4426732A4/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP22889542.1A 2021-11-02 2022-11-01 An porphyromonas gingivalis bindende antigenbindende moleküle Pending EP4426732A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/US2021/057758 WO2022098661A1 (en) 2020-11-03 2021-11-02 Antigen-binding molecules that bind to porphyromonas gingivalis
US202263364182P 2022-05-04 2022-05-04
US202263364592P 2022-05-12 2022-05-12
US18/051,456 US20230365662A1 (en) 2020-11-03 2022-10-31 Antigen-binding molecules that bind to porphyromonas gingivalis
PCT/IB2022/060535 WO2023079442A2 (en) 2021-11-02 2022-11-01 Antigen-binding molecules that bind to porphyromonas gingivalis

Publications (2)

Publication Number Publication Date
EP4426732A2 EP4426732A2 (de) 2024-09-11
EP4426732A4 true EP4426732A4 (de) 2025-10-08

Family

ID=86240877

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22889542.1A Pending EP4426732A4 (de) 2021-11-02 2022-11-01 An porphyromonas gingivalis bindende antigenbindende moleküle

Country Status (2)

Country Link
EP (1) EP4426732A4 (de)
WO (1) WO2023079442A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4213801A4 (de) * 2020-11-03 2025-01-01 Keystone Bio, Inc. An porphyromonas gingivalis bindende antigenbindende moleküle
AU2022205389A1 (en) * 2021-01-11 2023-07-13 Keystone Bio, Inc. Antigenic composition(s) and method(s) against porphyromonas gingivalis for the prevention and/or treatment of infection and/or diseases

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022098661A1 (en) * 2020-11-03 2022-05-12 Keystone Bio, Inc. Antigen-binding molecules that bind to porphyromonas gingivalis
WO2022150719A2 (en) * 2021-01-11 2022-07-14 Keystone Bio, Inc. Antigenic composition(s) and method(s) of use against porphyromonas gingivalis for the prevention and/or treatment of infection and/or diseases
WO2023288204A1 (en) * 2021-07-13 2023-01-19 Keystone Bio, Inc. Diagnostics for porphyromonas gingivalis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022098661A1 (en) * 2020-11-03 2022-05-12 Keystone Bio, Inc. Antigen-binding molecules that bind to porphyromonas gingivalis
WO2022150719A2 (en) * 2021-01-11 2022-07-14 Keystone Bio, Inc. Antigenic composition(s) and method(s) of use against porphyromonas gingivalis for the prevention and/or treatment of infection and/or diseases
WO2023288204A1 (en) * 2021-07-13 2023-01-19 Keystone Bio, Inc. Diagnostics for porphyromonas gingivalis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
H. MARCOTTE ET AL: "Expression of single-chain antibody against RgpA protease of Porphyromonas gingivalis in Lactobacillus", JOURNAL OF APPLIED MICROBIOLOGY, vol. 100, no. 2, 1 February 2006 (2006-02-01), pages 256 - 263, XP055661030, ISSN: 1364-5072, DOI: 10.1111/j.1365-2672.2005.02786.x *

Also Published As

Publication number Publication date
WO2023079442A2 (en) 2023-05-11
WO2023079442A9 (en) 2023-08-31
EP4426732A2 (de) 2024-09-11

Similar Documents

Publication Publication Date Title
EP4213801A4 (de) An porphyromonas gingivalis bindende antigenbindende moleküle
IL280919A (en) Methods of treating aging-related disorders
EP3606956C0 (de) Neuartige bispezifische antigenbindende moleküle zur spezifische bindung an cd40 und an fap
DK3773737T3 (da) Saponin konjugeret til epitop-bindende proteiner
IL286567A (en) Small molecule degraders of stat3
EP3514180C0 (de) Zur wiederholten bindung an zwei oder mehr antigenmoleküle fähiges, antigenbindendes molekül
DK3433273T3 (da) Binding af molekyler til cd38 og pd-l1
PT3781943T (pt) Qualificação da coluna de cromatografia em métodos de fabrico para produzir composições de anticorpos anti-il12/il23
IL290371A (en) Novel antigen binding molecule formats
EP4365293A4 (de) An clostridium difficile bindender antikörper
IL286013A (en) Cd3 binding molecules
WO2023079442A9 (en) Antigen-binding molecules that bind to porphyromonas gingivalis
EP4522758A4 (de) Abca4-transspleissmoleküle
EP4339213A4 (de) Antigenbindende moleküle
EP3774922A4 (de) Zellverknüpfende bindungsmoleküle
EP3976102A4 (de) Immunhemmende anti-gal9-bindungsmoleküle
EP4359794A4 (de) Diagnostika für porphyromonas gingivalis
EA201690334A1 (ru) Экстракт filipendula vulgaris (таволги обыкновенной) и его применение
IL318931A (en) Multi-domain binding molecules
IL288562A (en) Activating anti-gal9 binding molecules
SI4172199T1 (sl) PROTITELESA, Kl SE VEŽEJO NA PROTOFIBRILE ALFA-SINUKLEINA
PL4475844T3 (pl) Sposób otrzymywania maribawiru
EP4225806A4 (de) Konjugate zur verbesserung der gesamten zellulären akkumulation
EP4467573A4 (de) Bispezifisches bindungsmolekül
EP4302320A4 (de) Behandlungen zur verbesserung der vorrichtungsleistung

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20240530

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20250905

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 16/12 20060101AFI20250901BHEP

Ipc: A61K 39/40 20060101ALI20250901BHEP