EP4440577A4 - Composition à libération retardée comprenant de la doxylamine et de la pyridoxine - Google Patents

Composition à libération retardée comprenant de la doxylamine et de la pyridoxine

Info

Publication number
EP4440577A4
EP4440577A4 EP21966535.3A EP21966535A EP4440577A4 EP 4440577 A4 EP4440577 A4 EP 4440577A4 EP 21966535 A EP21966535 A EP 21966535A EP 4440577 A4 EP4440577 A4 EP 4440577A4
Authority
EP
European Patent Office
Prior art keywords
pyridoxin
doxylamine
delayed
release composition
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21966535.3A
Other languages
German (de)
English (en)
Other versions
EP4440577A1 (fr
Inventor
Hatice Oncel
Onur Pinarbasli
Feristah Bilgin
Ozgen Bahar Koksel
Nurdan Atilgan
Doganay Asuman Aybey
Nagehan Sarracoglu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ilko Ilac Sanayi ve Ticaret AS
Original Assignee
Ilko Ilac Sanayi ve Ticaret AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ilko Ilac Sanayi ve Ticaret AS filed Critical Ilko Ilac Sanayi ve Ticaret AS
Publication of EP4440577A1 publication Critical patent/EP4440577A1/fr
Publication of EP4440577A4 publication Critical patent/EP4440577A4/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP21966535.3A 2021-11-30 2021-11-30 Composition à libération retardée comprenant de la doxylamine et de la pyridoxine Pending EP4440577A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/TR2021/051318 WO2023101620A1 (fr) 2021-11-30 2021-11-30 Composition à libération retardée comprenant de la doxylamine et de la pyridoxine

Publications (2)

Publication Number Publication Date
EP4440577A1 EP4440577A1 (fr) 2024-10-09
EP4440577A4 true EP4440577A4 (fr) 2025-11-05

Family

ID=86612891

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21966535.3A Pending EP4440577A4 (fr) 2021-11-30 2021-11-30 Composition à libération retardée comprenant de la doxylamine et de la pyridoxine

Country Status (2)

Country Link
EP (1) EP4440577A4 (fr)
WO (1) WO2023101620A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2432945A1 (fr) * 2003-07-10 2003-09-28 Duchesnay Inc. Utilisation d'un succinate de doxylamine et de chlorhydrate de pyridoxinium pour la prophylaxie et le traitement des nausees post-chirurgical
WO2013082706A1 (fr) * 2011-12-07 2013-06-13 Pharmascience Inc. Formulation de doxylamine et de pyridoxine à libération prolongée sans délitant et procédé de fabrication associé
CN103432126A (zh) * 2013-08-05 2013-12-11 北京阜康仁生物制药科技有限公司 一种治疗孕吐的药物组合物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2432945A1 (fr) * 2003-07-10 2003-09-28 Duchesnay Inc. Utilisation d'un succinate de doxylamine et de chlorhydrate de pyridoxinium pour la prophylaxie et le traitement des nausees post-chirurgical
WO2013082706A1 (fr) * 2011-12-07 2013-06-13 Pharmascience Inc. Formulation de doxylamine et de pyridoxine à libération prolongée sans délitant et procédé de fabrication associé
CN103432126A (zh) * 2013-08-05 2013-12-11 北京阜康仁生物制药科技有限公司 一种治疗孕吐的药物组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2023101620A1 *

Also Published As

Publication number Publication date
WO2023101620A1 (fr) 2023-06-08
EP4440577A1 (fr) 2024-10-09

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/4402 20060101AFI20250930BHEP

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