EP4457356A4 - Zusammensetzungen und verfahren zur identifizierung von genfusionen - Google Patents
Zusammensetzungen und verfahren zur identifizierung von genfusionenInfo
- Publication number
- EP4457356A4 EP4457356A4 EP22910350.2A EP22910350A EP4457356A4 EP 4457356 A4 EP4457356 A4 EP 4457356A4 EP 22910350 A EP22910350 A EP 22910350A EP 4457356 A4 EP4457356 A4 EP 4457356A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- genfusions
- identifying
- compositions
- methods
- identifying genfusions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163293711P | 2021-12-24 | 2021-12-24 | |
| PCT/IB2022/062748 WO2023119252A1 (en) | 2021-12-24 | 2022-12-23 | Compositions and methods for identification of gene fusions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4457356A1 EP4457356A1 (de) | 2024-11-06 |
| EP4457356A4 true EP4457356A4 (de) | 2025-10-29 |
Family
ID=86901551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP22910350.2A Pending EP4457356A4 (de) | 2021-12-24 | 2022-12-23 | Zusammensetzungen und verfahren zur identifizierung von genfusionen |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP4457356A4 (de) |
| AU (1) | AU2022422775A1 (de) |
| CA (1) | CA3242158A1 (de) |
| WO (1) | WO2023119252A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118398081B (zh) * | 2024-06-26 | 2024-10-22 | 杭州联川生物技术股份有限公司 | 一种基于rna测序分析融合基因类型的方法、系统、设备和介质 |
| CN119091966A (zh) * | 2024-09-03 | 2024-12-06 | 浙江洛兮医学检验实验室有限公司 | 一种用于检测高通量测序数据中融合基因的方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2914743B1 (de) * | 2012-11-02 | 2019-08-07 | Life Technologies Corporation | Erfassung, detektion und quantifizierung von kleiner rna |
| WO2020106893A1 (en) * | 2018-11-21 | 2020-05-28 | Karius, Inc. | Direct-to-library methods, systems, and compositions |
| US20210222161A1 (en) * | 2018-06-06 | 2021-07-22 | The Regents Of The University Of California | Methods of Producing Nucleic Acid Libraries and Compositions and Kits for Practicing Same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8790873B2 (en) * | 2009-01-16 | 2014-07-29 | Affymetrix, Inc. | DNA ligation on RNA template |
| US10597710B2 (en) * | 2012-12-21 | 2020-03-24 | New England Biolabs, Inc. | Ligase activity |
| US10597650B2 (en) * | 2012-12-21 | 2020-03-24 | New England Biolabs, Inc. | Ligase activity |
| US10964410B2 (en) * | 2017-05-25 | 2021-03-30 | Koninklijke Philips N.V. | System and method for detecting gene fusion |
| CN115136241A (zh) * | 2020-02-14 | 2022-09-30 | 夸登特健康公司 | 用于确定融合事件的方法和系统 |
-
2022
- 2022-12-23 AU AU2022422775A patent/AU2022422775A1/en active Pending
- 2022-12-23 CA CA3242158A patent/CA3242158A1/en active Pending
- 2022-12-23 EP EP22910350.2A patent/EP4457356A4/de active Pending
- 2022-12-23 WO PCT/IB2022/062748 patent/WO2023119252A1/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2914743B1 (de) * | 2012-11-02 | 2019-08-07 | Life Technologies Corporation | Erfassung, detektion und quantifizierung von kleiner rna |
| US20210222161A1 (en) * | 2018-06-06 | 2021-07-22 | The Regents Of The University Of California | Methods of Producing Nucleic Acid Libraries and Compositions and Kits for Practicing Same |
| WO2020106893A1 (en) * | 2018-11-21 | 2020-05-28 | Karius, Inc. | Direct-to-library methods, systems, and compositions |
Non-Patent Citations (1)
| Title |
|---|
| SEAN MAGUIRE ET AL: "A low-bias and sensitive small RNA librarypreparation method using randomized splint ligation", NUCLEIC ACIDS RESEARCH, vol. 48, no. 14, 4 June 2020 (2020-06-04), GB, pages e80 - e80, XP055725025, ISSN: 0305-1048, DOI: 10.1093/nar/gkaa480 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2022422775A1 (en) | 2024-08-08 |
| AU2022422775A9 (en) | 2024-08-15 |
| WO2023119252A1 (en) | 2023-06-29 |
| EP4457356A1 (de) | 2024-11-06 |
| CA3242158A1 (en) | 2023-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20240723 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/6806 20180101AFI20250701BHEP Ipc: C12N 15/10 20060101ALI20250701BHEP Ipc: C12Q 1/68 20180101ALI20250701BHEP Ipc: C40B 40/02 20060101ALI20250701BHEP Ipc: C40B 50/06 20060101ALI20250701BHEP Ipc: G16B 20/00 20190101ALI20250701BHEP Ipc: G16B 30/00 20190101ALI20250701BHEP Ipc: C12Q 1/6827 20180101ALI20250701BHEP Ipc: C12Q 1/70 20060101ALI20250701BHEP |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20250929 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/6806 20180101AFI20250923BHEP Ipc: C12N 15/10 20060101ALI20250923BHEP Ipc: C12Q 1/68 20180101ALI20250923BHEP Ipc: C40B 40/02 20060101ALI20250923BHEP Ipc: C40B 50/06 20060101ALI20250923BHEP Ipc: G16B 20/00 20190101ALI20250923BHEP Ipc: G16B 30/00 20190101ALI20250923BHEP Ipc: C12Q 1/6827 20180101ALI20250923BHEP Ipc: C12Q 1/70 20060101ALI20250923BHEP |