EP4472941A4 - Procédé de production de lipides ionisables ou d'intermédiaires pour la synthèse de tels lipides - Google Patents
Procédé de production de lipides ionisables ou d'intermédiaires pour la synthèse de tels lipidesInfo
- Publication number
- EP4472941A4 EP4472941A4 EP23749311.9A EP23749311A EP4472941A4 EP 4472941 A4 EP4472941 A4 EP 4472941A4 EP 23749311 A EP23749311 A EP 23749311A EP 4472941 A4 EP4472941 A4 EP 4472941A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- lipids
- synthesis
- production
- intermediate products
- ionizable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/26—Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups B01J31/02 - B01J31/24
- B01J31/38—Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups B01J31/02 - B01J31/24 of titanium, zirconium or hafnium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C7/00—Purification; Separation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Analytical Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263305827P | 2022-02-02 | 2022-02-02 | |
| PCT/CA2023/050129 WO2023147657A1 (fr) | 2022-02-02 | 2023-01-31 | Procédé de production de lipides ionisables ou d'intermédiaires pour la synthèse de tels lipides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4472941A1 EP4472941A1 (fr) | 2024-12-11 |
| EP4472941A4 true EP4472941A4 (fr) | 2026-02-25 |
Family
ID=87553118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP23749311.9A Pending EP4472941A4 (fr) | 2022-02-02 | 2023-01-31 | Procédé de production de lipides ionisables ou d'intermédiaires pour la synthèse de tels lipides |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20250162968A1 (fr) |
| EP (1) | EP4472941A4 (fr) |
| CA (1) | CA3243452A1 (fr) |
| WO (1) | WO2023147657A1 (fr) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013086322A1 (fr) * | 2011-12-07 | 2013-06-13 | Alnylam Pharmaceuticals, Inc. | Lipides biodégradables ramifiés à terminaisons alkyle et cycloalkyle destinés à l'administration d'agents actifs |
-
2023
- 2023-01-31 EP EP23749311.9A patent/EP4472941A4/fr active Pending
- 2023-01-31 WO PCT/CA2023/050129 patent/WO2023147657A1/fr not_active Ceased
- 2023-01-31 CA CA3243452A patent/CA3243452A1/fr active Pending
- 2023-01-31 US US18/834,843 patent/US20250162968A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013086322A1 (fr) * | 2011-12-07 | 2013-06-13 | Alnylam Pharmaceuticals, Inc. | Lipides biodégradables ramifiés à terminaisons alkyle et cycloalkyle destinés à l'administration d'agents actifs |
Non-Patent Citations (2)
| Title |
|---|
| CLEMENT ET AL: "Sur une m�thode de pr�paration du nonad�canedio�que-1,19", COMPTES RENDUS DES S�ANCES DE L'ACAD�MIE DES SCIENCES / C,, vol. 254, 30 November 1961 (1961-11-30), pages 2794 - 2795, XP009548067 * |
| See also references of WO2023147657A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023147657A1 (fr) | 2023-08-10 |
| CA3243452A1 (fr) | 2023-08-10 |
| US20250162968A1 (en) | 2025-05-22 |
| EP4472941A1 (fr) | 2024-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20240902 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20260126 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07C 45/57 20060101AFI20260120BHEP Ipc: C07C 49/17 20060101ALI20260120BHEP Ipc: C07C 51/09 20060101ALI20260120BHEP Ipc: C07C 59/347 20060101ALI20260120BHEP Ipc: C07C 51/38 20060101ALI20260120BHEP Ipc: C07C 7/00 20060101ALI20260120BHEP Ipc: C07F 7/18 20060101ALI20260120BHEP |