EP4480454A2 - Conception de cafe d'endoprothèse alternative pour tavr - Google Patents

Conception de cafe d'endoprothèse alternative pour tavr Download PDF

Info

Publication number
EP4480454A2
EP4480454A2 EP24204552.4A EP24204552A EP4480454A2 EP 4480454 A2 EP4480454 A2 EP 4480454A2 EP 24204552 A EP24204552 A EP 24204552A EP 4480454 A2 EP4480454 A2 EP 4480454A2
Authority
EP
European Patent Office
Prior art keywords
stent
attachment features
commissure attachment
leaflets
commissure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24204552.4A
Other languages
German (de)
English (en)
Other versions
EP4480454A3 (fr
Inventor
Richard Kaleta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Medical Cardiology Division Inc
Original Assignee
St Jude Medical Cardiology Division Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Jude Medical Cardiology Division Inc filed Critical St Jude Medical Cardiology Division Inc
Publication of EP4480454A2 publication Critical patent/EP4480454A2/fr
Publication of EP4480454A3 publication Critical patent/EP4480454A3/fr
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418—Scaffolds therefor, e.g. support stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415—Manufacturing methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0036—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in thickness

Definitions

  • the present invention relates to collapsible prosthetic heart valves, and more particularly, to prosthetic heart valves having commissure attachment features that reduce strain on the leaflets of the prosthetic valve and methods of manufacturing the commissure attachment features.
  • Prosthetic heart valves that are collapsible to a relatively small circumferential size can be delivered into a patient less invasively than valves that are not collapsible.
  • a collapsible valve may be delivered into a patient via a tube-like delivery apparatus such as a catheter, a trocar, a laparoscopic instrument, or the like. This collapsibility can avoid the need for a more invasive procedure such as full open-chest, open-heart surgery.
  • Collapsible prosthetic heart valves typically take the form of a valve structure mounted on a stent.
  • a stent There are two types of stents on which the valve structures are ordinarily mounted: a self-expanding stent and a balloon-expandable stent.
  • a self-expanding stent To place such valves into a delivery apparatus and ultimately into a patient, the valve must first be collapsed to reduce its circumferential size.
  • the prosthetic valve When a collapsed prosthetic valve has reached the desired implant site in the patient (e.g., at or near the annulus of the patient's heart valve that is to be repaired by the prosthetic valve), the prosthetic valve can be deployed or released from the delivery apparatus and expanded to its full operating size.
  • the desired implant site in the patient e.g., at or near the annulus of the patient's heart valve that is to be repaired by the prosthetic valve
  • the prosthetic valve can be deployed or released from the delivery apparatus and expanded to its full operating size.
  • this generally involves releasing the entire valve, assuring its proper location and then expanding a balloon positioned within the valve stent.
  • the stent automatically expands as the stent is withdrawn from the delivery apparatus.
  • Prosthetic aortic heart valves maintain unidirectional blood flow in the circulatory system by opening and closing, depending on the difference in the pressure on opposite sides of the valve. Prosthetic aortic heart valves prevent backflow from the aorta into the left ventricle during systole.
  • prosthetic heart valves have limited life expectancies for a variety of reasons. Thrombus buildup, for example, may prevent the prosthetic leaflets from properly coapting. Moreover, the prosthetic heart valve may be susceptible to failure at high stress regions, such as the leaflet commissure attachment feature, causing the prosthetic leaflets to tear and/or the sutures that attach the prosthetic valve assembly to the stent to tear.
  • a commissure attachment feature extends in a medial direction of a stent for coupling a valve assembly to the stent.
  • this attachment feature permits adjacent leaflets to be sutured to one another to improve blood washout of the neo-sinus of the prosthetic heart valve to prevent the formation of thrombus, and to redistribute strain from the commissure of the leaflets to the stent. Redistributing the strain in this manner reduces the likelihood that the prosthetic leaflets will tear.
  • One embodiment of the device includes a stent extending in a longitudinal direction and having a collapsed condition and an expanded condition.
  • the stent includes a plurality of struts forming cells and a plurality of commissure attachment features spaced apart in an annular direction of the stent.
  • Each of the commissure attachment features is attached to select ones of the struts and extends in a medial direction of the stent.
  • a valve assembly is secured to the plurality of commissure attachment features, the valve assembly including a cuff and a plurality of leaflets, each of the leaflets having a free edge and being capable of alternating between an open position and a closed position.
  • a method of manufacturing a prosthetic heart valve includes cutting a tubular material to form a stent, the stent extending in a longitudinal direction and having a collapsed condition and an expanded condition.
  • the stent includes a plurality of struts forming cells and a plurality of commissure attachment features spaced apart in an annular direction of the stent.
  • the method further includes bending each of the commissure attachment features from a first orientation to a second orientation different from the first orientation, and coupling a valve assembly to the commissure attachment features, the valve assembly including a cuff and a plurality of leaflets, each of the leaflets having a free edge and being capable of alternating between an open position and a closed position.
  • proximal when used in connection with a prosthetic heart valve, refers to the end of the heart valve closest to the heart when the heart valve is implanted in a patient
  • distal when used in connection with a prosthetic heart valve, refers to the end of the heart valve farthest from the heart when the heart valve is implanted in a patient.
  • the terms “generally,” “substantially,” “approximately” and “about” are intended to mean that slight deviations from absolute are included within the scope of the term so modified.
  • FIG. 1 illustrates a collapsible prosthetic heart valve 10 that is designed to replace the function of the native aortic valve of a patient.
  • Prosthetic heart valve 10 includes an expandable stent 12 which may be formed from biocompatible materials that are capable of self-expansion, for example, shape memory alloys such as nitinol.
  • Stent 12 extends from a proximal or annulus end 14 to a distal or aortic end 16, and includes an annulus section 18 adjacent the proximal end and an aortic section 20 adjacent the distal end.
  • Annulus section 18 has a relatively small cross-section in an expanded condition compared to aortic section 20 in the expanded condition.
  • Annulus section 18 maybe in the form of a cylinder having a substantially constant diameter along its length.
  • a transition section 22 tapers outwardly from annulus section 18 to aortic section 20.
  • Each of the sections of stent 12 includes a plurality of struts 24 which form a plurality of cells 26 that are connected to one another in one or more annular rows around the stent.
  • Annulus section 18 may have two annular rows of complete cells and aortic section 20 and transition section 22 may each have one or more annular rows of partial cells.
  • the cells in aortic section 20 may be larger than the cells in annulus section 18.
  • the larger cells in aortic section 20 facilitate positioning prosthetic valve 10 within the native aortic annulus such that stent 12 does not interfere with blood flow to the coronary arteries.
  • Stent 12 includes one or more retaining elements 28 at distal end 16.
  • Retaining elements 28 are sized to cooperate with a corresponding retaining structure on a delivery device. This cooperation minimizes axial movement of the prosthetic heart valve relative to the delivery device during unsheathing or resheathing procedures, and prevents rotation of the prosthetic heart valve relative to the delivery device as the delivery device is advanced to the target location and during deployment.
  • Stent 12 may also include a plurality of commissure attachment features 30 for attaching the commissure between two adjacent leaflets to the stent.
  • commissure attachments features 30 are disposed within the wall of stent 12 and may lie at the intersection of four cells 26, two of the cells being adjacent to one another in the same annular row, and the other two cells being in different annular rows and lying in end-to-end relationship.
  • Commissure attachment features 30 are preferably positioned entirely within annulus section 18, or at the juncture of the annulus section and transition section 22.
  • Commissure attachment features 30 may include one or more eyelets 32 which facilitate the suturing of the leaflet commissure to stent 12.
  • Prosthetic heart valve 10 also includes a valve assembly 34, which may be positioned entirely within annulus section 18 and secured to stent 12 by suturing the valve assembly to struts 24 and/or to commissure attachment features 30. That is, the entire valve assembly 34 may be axially positioned between the proximal end 14 of stent 12 and commissure attachment features 30, such that none of the valve assembly is positioned between the commissure attachment features and the distal end 16 of the stent.
  • Valve assembly 34 includes a cuff 36 and a plurality of leaflets 38 which open and close collectively to function as a one-way valve. Both cuff 36 and leaflets 38 may be wholly or partly formed of any suitable biological material, such as bovine or porcine pericardium, or biocompatible polymers, such as PTFE, urethanes and the like.
  • Prosthetic heart valve 10 may be used to replace a native valve, a surgical heart valve or a heart valve that has undergone a surgical procedure.
  • Prosthetic heart valve 10 may be delivered to the desired site (e.g., near the native aortic annulus) using any suitable delivery device.
  • prosthetic heart valve 10 is disposed inside the delivery device in a collapsed condition.
  • the delivery device may be introduced into a patient using a transfemoral, transapical, transseptal or any other percutaneous approach.
  • the user may deploy prosthetic heart valve 10.
  • prosthetic heart valve 10 expands so that the annulus section 18 of stent 12 is in secure engagement within the native annulus.
  • FIG. 2 is a highly schematic cutaway view showing prosthetic heart valve 10 disposed within the native aortic annulus of a patient.
  • prosthetic heart valve 10 When prosthetic heart valve 10 is properly positioned within the native annulus, it works as a one-way valve, allowing blood to flow from the left ventricle of the heart to the aorta during systole, and preventing blood from flowing in the opposite direction.
  • Long term clinical success, and ultimately the life of prosthetic heart valve 10 is dependent, in part, on the ability of the free edges of leaflets 38 to properly coapt. Thrombus buildup in the neo-sinus NS of prosthetic heart valve 10 may restrict motion of leaflets 38 and prevent the leaflets from coapting.
  • FIG. 4 illustrates a prosthetic heart valve 110 according to an embodiment of the present invention.
  • Prosthetic heart valve 110 includes all of the features of prosthetic heart valve 10, except for commissure attachment features 30. Accordingly, each of the features of prosthetic heart valve 110 that correspond to features of prosthetic heart valve 10 are not described again hereinafter. Instead, when such features are referenced or illustrated in FIGS. 4-7 , these features are described and illustrated using corresponding 100 series numerals.
  • Prosthetic heart valve 110 replaces commissure attachment features 30 with commissure attachment features 130, shown in Fig. 5 .
  • Commissure attachment features 130 are designed to redistribute strain from the leaflets 138 of prosthetic heart valve 110 to the stent 112 of the prosthetic heart valve.
  • Commissure attachment features 130 are spaced apart from one another in an annular direction of stent 112 and disposed within a predetermined one of the annular rows of cells 126.
  • commissure attachment features 130 are disposed in one of the rows of cells within the annulus section 118 of stent 112, or in one of the rows of cells at the juncture of the annulus section and the transition section 122 of the stent. Since FIG.
  • prosthetic heart valve 110 for replacing a native tricuspid valve, such as the aortic valve
  • prosthetic heart valve 110 is illustrated with three leaflets 138, as well as three commissure attachment features 130.
  • prosthetic heart valves according to this aspect of the invention may have a greater or lesser number of leaflets 138 and/or commissure attachment features 130.
  • the prosthetic heart valve may include two commissure attachment features 130 for attaching each of the two prosthetic leaflets 138 to stent 112.
  • each one of the plurality of commissure attachment features 130 includes a body 140 that has a length in a longitudinal direction of stent 112, a width in a radial direction of the stent and a thickness (not shown) in an annular direction of the stent.
  • the width of body 140 may be about 3.0 mm or less, and is preferably between about 2.0 mm and about 2.5 mm.
  • Commissure attachment features 130 may be positioned above the bulk of leaflets 138. In light of this and that the commissure attachment features have a relatively small dimension in the medial direction of stent 112, the collapsibility of prosthetic heart valve 110 is not inhibited. Accordingly, prosthetic heart valve 110 can be collapsed into a competitive French delivery system, for example, an 18 French delivery device.
  • the body 140 of commissure attachment feature 130 has a side 142 that is attached to select struts 124 of stent 112, and a free edge 144 that is disposed in an interior region the stent. That is, the body 140 of commissure attachment feature 130 extends from select struts 124 in a medial direction of stent 112 (i.e., toward the middle of the stent or radially inward). In other words, body 140 extends orthogonal to the annular direction of stent 112 toward the center of the stent.
  • the body 140 of commissure attachment feature 130 may be shaped as a quarter ellipse, or a quarter circle, such that the free edge 144 of the body forms an arc extending from a distal end of the attached side 142 of the body to a proximal end of the free edge spaced radially inward from stent 112.
  • the body 140 of commissure attachment feature 130 may include a plurality of apertures or eyelets for connecting valve assembly 134 to stent 112.
  • body 140 may include an eyelet 146 for coupling cuff 136 to stent 112, and one or more smaller eyelets 148 for suturing adjacent leaflets 138 to one another and to the commissure attachment feature.
  • At least one of leaflet attachment eyelets 148 may be spaced from the attached side 142 of commissure attachment feature 130 so as to be spaced from a luminal surface of stent 112.
  • FIG. 6 is a flow chart depicting a method 200 of manufacturing prosthetic heart valve 110.
  • a tube of nitinol is placed around a mandrel and cut, preferably by a laser or other technique, to form stent 112.
  • FIG. 7 A fragmentary view of stent 112 after the tube has been cut and radially expanded is illustrated in FIG. 7 .
  • commissure attachment features 130 initially extend in a lateral direction relative to the struts 124 of stent 112. That is, commissure attachment features 130 initially lie within the circumference of stent 112.
  • commissure attachment features 130 are then heat set, or otherwise permanently set, in this position.
  • cuff 136 may be attached to stent 112 in step 206, for example, by suturing the cuff to the stent.
  • a suture may additionally be pierced through cuff 136 and passed through the cuff attachment eyelet 146 of commissure attachment feature 130 before the suture is again pierced through the cuff.
  • This additional step may optionally be repeated for each one of commissure attachment features 130.
  • the ends of adjacent leaflets may then be sutured together and coupled to the commissure attachment feature 130.
  • a suture may pierce through a first one of the leaflets, pass through at least one of the leaflet attachment eyelets 148 of commissure attachment feature 130, and then pierce through an adjacent leaflet.
  • the belly of each one of leaflets 138 may then be sutured to cuff 136 and stent 112.
  • a series of suture loops extend along the belly of each one of the leaflets in a parabolic shape, and further secure the leaflets to the stent.
  • the cross-sectional area of the lumen of prosthetic heart valve 110 is reduced, such that the velocity of blood flow through the lumen during systole will be increased.
  • some of the blood will form an eddy in the neo-sinus, and wash out from the neo-sinus is improved and thrombus build up is reduced.
  • adjacent leaflets are sutured together via medially extending commissure attachment features 130, when a stress is applied to the prosthetic valve leaflets 138, the stress is transferred away from the prosthetic leaflets to the commissure attachment features and stent 112. This reduces the likelihood that valve assembly 134 will fail under stress and prolongs the life of prosthetic heart valve 110.
  • a prosthetic heart valve includes a stent extending in a longitudinal direction and having a collapsed condition and an expanded condition, the stent including a plurality of struts forming cells and a plurality of commissure attachment features spaced apart in an annular direction of the stent, each of the commissure attachment features being attached to select ones of the struts and extending in a medial direction of the stent; and a valve assembly secured to the plurality of the commissure attachment features, the valve assembly including a cuff and a plurality of leaflets, each of the leaflets having a free edge and being capable of alternating between an open position and a closed position; and/or
  • a method of manufacturing a prosthetic heart valve includes cutting a tubular material to form a stent, the stent extending in a longitudinal direction and having a collapsed condition and an expanded condition, the stent including a plurality of struts forming cells and a plurality of commissure attachment features spaced apart in an annular direction of the stent; bending each of the commissure attachment features from a first orientation to a second orientation different from the first orientation; and coupling a valve assembly to the commissure attachment features, the valve assembly including a cuff and a plurality of leaflets, each of the leaflets having a free edge and being capable of alternating between an open position and a closed position; and/or

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Prostheses (AREA)
EP24204552.4A 2019-07-31 2020-07-20 Conception de cafe d'endoprothèse alternative pour tavr Pending EP4480454A3 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962880758P 2019-07-31 2019-07-31
EP20753609.5A EP4003230B1 (fr) 2019-07-31 2020-07-20 Conception alternée d'endoprothèse caf pour rvac
PCT/US2020/042776 WO2021021482A1 (fr) 2019-07-31 2020-07-20 Conception alternée d'endoprothèse caf pour rvac

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP20753609.5A Division EP4003230B1 (fr) 2019-07-31 2020-07-20 Conception alternée d'endoprothèse caf pour rvac
EP20753609.5A Division-Into EP4003230B1 (fr) 2019-07-31 2020-07-20 Conception alternée d'endoprothèse caf pour rvac

Publications (2)

Publication Number Publication Date
EP4480454A2 true EP4480454A2 (fr) 2024-12-25
EP4480454A3 EP4480454A3 (fr) 2025-07-09

Family

ID=71995147

Family Applications (2)

Application Number Title Priority Date Filing Date
EP20753609.5A Active EP4003230B1 (fr) 2019-07-31 2020-07-20 Conception alternée d'endoprothèse caf pour rvac
EP24204552.4A Pending EP4480454A3 (fr) 2019-07-31 2020-07-20 Conception de cafe d'endoprothèse alternative pour tavr

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP20753609.5A Active EP4003230B1 (fr) 2019-07-31 2020-07-20 Conception alternée d'endoprothèse caf pour rvac

Country Status (3)

Country Link
US (2) US11672654B2 (fr)
EP (2) EP4003230B1 (fr)
WO (1) WO2021021482A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11833034B2 (en) 2016-01-13 2023-12-05 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
JP7421546B2 (ja) 2018-08-21 2024-01-24 シファメド・ホールディングス・エルエルシー 人工心弁デバイス、システム、および方法
US10912644B2 (en) 2018-10-05 2021-02-09 Shifamed Holdings, Llc Prosthetic cardiac valve devices, systems, and methods
JP7489975B2 (ja) 2018-10-19 2024-05-24 シファメド・ホールディングス・エルエルシー 調整可能な医療デバイス
EP4505968A3 (fr) 2019-03-19 2025-05-07 Shifamed Holdings, LLC Dispositifs de valvule cardiaque prothétique, systèmes
US20240415642A1 (en) * 2020-04-24 2024-12-19 ReValve Solutions Inc. Devices, systems, and methods for a valve replacement
EP4203860A4 (fr) 2020-08-31 2024-10-09 Shifamed Holdings, LLC Système de pose d'implant prothétique
IL301478A (en) 2020-09-23 2023-05-01 Revalve Solutions Inc Devices, systems and methods for an implantable heart valve adapter
JP7835754B2 (ja) 2020-12-04 2026-03-25 シファメド・ホールディングス・エルエルシー 張り出し人工心弁送達デバイスおよびシステム
US12201521B2 (en) 2021-03-22 2025-01-21 Shifamed Holdings, Llc Anchor position verification for prosthetic cardiac valve devices

Family Cites Families (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657744A (en) 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US4491986A (en) 1976-05-12 1985-01-08 Shlomo Gabbay Heart valve
US4275469A (en) 1979-12-13 1981-06-30 Shelhigh Inc. Prosthetic heart valve
US4759758A (en) 1984-12-07 1988-07-26 Shlomo Gabbay Prosthetic heart valve
DE3640745A1 (de) 1985-11-30 1987-06-04 Ernst Peter Prof Dr M Strecker Katheter zum herstellen oder erweitern von verbindungen zu oder zwischen koerperhohlraeumen
US4878906A (en) 1986-03-25 1989-11-07 Servetus Partnership Endoprosthesis for repairing a damaged vessel
US4994077A (en) 1989-04-21 1991-02-19 Dobben Richard L Artificial heart valve for implantation in a blood vessel
US5411552A (en) 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
US5843167A (en) 1993-04-22 1998-12-01 C. R. Bard, Inc. Method and apparatus for recapture of hooked endoprosthesis
US5480423A (en) 1993-05-20 1996-01-02 Boston Scientific Corporation Prosthesis delivery
US5713950A (en) 1993-11-01 1998-02-03 Cox; James L. Method of replacing heart valves using flexible tubes
ES2135520T3 (es) 1993-11-04 1999-11-01 Bard Inc C R Protesis vascular no migrante.
US5415664A (en) 1994-03-30 1995-05-16 Corvita Corporation Method and apparatus for introducing a stent or a stent-graft
GB9522332D0 (en) 1995-11-01 1996-01-03 Biocompatibles Ltd Braided stent
ATE218052T1 (de) 1995-11-27 2002-06-15 Schneider Europ Gmbh Stent zur anwendung in einem körperlichen durchgang
US7238197B2 (en) 2000-05-30 2007-07-03 Devax, Inc. Endoprosthesis deployment system for treating vascular bifurcations
US5855601A (en) 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
EP0850607A1 (fr) 1996-12-31 1998-07-01 Cordis Corporation Prothèse de valve pour implantation dans des canaux corporels
SG161732A1 (en) 1997-01-24 2010-06-29 Nexeon Medsystems Inc Expandable device having bistable spring construction
US5961549A (en) 1997-04-03 1999-10-05 Baxter International Inc. Multi-leaflet bioprosthetic heart valve
US5910170A (en) * 1997-12-17 1999-06-08 St. Jude Medical, Inc. Prosthetic heart valve stent utilizing mounting clips
US5938697A (en) 1998-03-04 1999-08-17 Scimed Life Systems, Inc. Stent having variable properties
US5935163A (en) 1998-03-31 1999-08-10 Shelhigh, Inc. Natural tissue heart valve prosthesis
US7452371B2 (en) 1999-06-02 2008-11-18 Cook Incorporated Implantable vascular device
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6214036B1 (en) 1998-11-09 2001-04-10 Cordis Corporation Stent which is easily recaptured and repositioned within the body
DE19857887B4 (de) 1998-12-15 2005-05-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerungsstütze für eine Herzklappenprothese
US6558414B2 (en) 1999-02-02 2003-05-06 Impra, Inc. Partial encapsulation of stents using strips and bands
US6090140A (en) 1999-02-17 2000-07-18 Shelhigh, Inc. Extra-anatomic heart valve apparatus
US6264691B1 (en) 1999-04-23 2001-07-24 Shlomo Gabbay Apparatus and method for supporting a heart valve
WO2001019285A1 (fr) 1999-09-10 2001-03-22 Patricia Ellen Thorpe Traitement endovasculaire des insuffisances veineuses chroniques
US6440164B1 (en) 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
US20070043435A1 (en) 1999-11-17 2007-02-22 Jacques Seguin Non-cylindrical prosthetic valve system for transluminal delivery
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
FR2800984B1 (fr) 1999-11-17 2001-12-14 Jacques Seguin Dispositif de remplacement d'une valve cardiaque par voie percutanee
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US6458153B1 (en) 1999-12-31 2002-10-01 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US7195641B2 (en) 1999-11-19 2007-03-27 Advanced Bio Prosthetic Surfaces, Ltd. Valvular prostheses having metal or pseudometallic construction and methods of manufacture
PL201632B1 (pl) 2000-01-31 2009-04-30 Cook Biotech Zespół zastawki stentu
US6454799B1 (en) * 2000-04-06 2002-09-24 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
US6610088B1 (en) 2000-05-03 2003-08-26 Shlomo Gabbay Biologically covered heart valve prosthesis
US6368348B1 (en) 2000-05-15 2002-04-09 Shlomo Gabbay Annuloplasty prosthesis for supporting an annulus of a heart valve
US6869444B2 (en) 2000-05-22 2005-03-22 Shlomo Gabbay Low invasive implantable cardiac prosthesis and method for helping improve operation of a heart valve
US6419695B1 (en) 2000-05-22 2002-07-16 Shlomo Gabbay Cardiac prosthesis for helping improve operation of a heart valve
WO2002022054A1 (fr) 2000-09-12 2002-03-21 Gabbay S Prothese valvulaire et son procede d'utilisation
US7510572B2 (en) 2000-09-12 2009-03-31 Shlomo Gabbay Implantation system for delivery of a heart valve prosthesis
US6685625B2 (en) 2000-09-26 2004-02-03 Shlomo Gabbay Curved implantable sheath and method of making same
US6783556B1 (en) 2000-09-26 2004-08-31 Shlomo Gabbay System and method for making a calotte-shaped implantable sheath
US20020036220A1 (en) 2000-09-26 2002-03-28 Shlomo Gabbay Curved implantable sheath and method of making same
US6517576B2 (en) 2000-12-11 2003-02-11 Shlomo Gabbay Implantable patch prosthesis having one or more cusps for improved competency
DE60115280T2 (de) 2000-12-15 2006-08-10 Angiomed Gmbh & Co. Medizintechnik Kg Stent mit herzklappe
US6468660B2 (en) 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
WO2002067782A2 (fr) 2001-02-26 2002-09-06 Ev3 Peripheral, Inc. Systeme de mise en place d'implant pourvu d'un dispositif de verrouillage
US6623518B2 (en) 2001-02-26 2003-09-23 Ev3 Peripheral, Inc. Implant delivery system with interlock
US7556646B2 (en) 2001-09-13 2009-07-07 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
DE10121210B4 (de) 2001-04-30 2005-11-17 Universitätsklinikum Freiburg Verankerungselement zur intraluminalen Verankerung eines Herzklappenersatzes und Verfahren zu seiner Herstellung
FR2828091B1 (fr) 2001-07-31 2003-11-21 Seguin Jacques Ensemble permettant la mise en place d'une valve prothetique dans un conduit corporel
US20080021552A1 (en) 2001-10-09 2008-01-24 Shlomo Gabbay Apparatus To Facilitate Implantation
US6893460B2 (en) 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve
DE10221076A1 (de) 2002-05-11 2003-11-27 Ruesch Willy Gmbh Stent
US7137184B2 (en) 2002-09-20 2006-11-21 Edwards Lifesciences Corporation Continuous heart valve support frame and method of manufacture
US6814746B2 (en) 2002-11-01 2004-11-09 Ev3 Peripheral, Inc. Implant delivery system with marker interlock
FR2847800B1 (fr) 2002-11-28 2005-10-14 Perouse Laboratoires Valve prothetique interchangeable
FR2850008A1 (fr) 2003-01-17 2004-07-23 Daniel Roux Prothese vasculaire permettant une adaptation aux differences de diametre entre les deux extremites d'un segment de vaisseau sanguin a remplacer
JP4473861B2 (ja) 2003-03-20 2010-06-02 エイオアテック、インターナショナル、ピーエルシー 弁
US7717952B2 (en) 2003-04-24 2010-05-18 Cook Incorporated Artificial prostheses with preferred geometries
EP1615595B1 (fr) 2003-04-24 2009-10-21 Cook Incorporated Prothese a valve artificielle, a dynamique d'ecoulement amelioree
US7201772B2 (en) 2003-07-08 2007-04-10 Ventor Technologies, Ltd. Fluid flow prosthetic device
US7160322B2 (en) 2003-08-13 2007-01-09 Shlomo Gabbay Implantable cardiac prosthesis for mitigating prolapse of a heart valve
US10219899B2 (en) 2004-04-23 2019-03-05 Medtronic 3F Therapeutics, Inc. Cardiac valve replacement systems
US20060259137A1 (en) 2003-10-06 2006-11-16 Jason Artof Minimally invasive valve replacement system
US20050137686A1 (en) 2003-12-23 2005-06-23 Sadra Medical, A Delaware Corporation Externally expandable heart valve anchor and method
DE10394350B4 (de) 2003-12-23 2018-05-17 Cormove In ein Lumen zu implantierender Teilesatz und Prothese denselben enthaltend
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US7311730B2 (en) 2004-02-13 2007-12-25 Shlomo Gabbay Support apparatus and heart valve prosthesis for sutureless implantation
US7247167B2 (en) 2004-02-19 2007-07-24 Shlomo Gabbay Low profile heart valve prosthesis
ITTO20040135A1 (it) 2004-03-03 2004-06-03 Sorin Biomedica Cardio Spa Protesi valvolare cardiaca
EP3308744B2 (fr) 2004-03-11 2023-08-02 Percutaneous Cardiovascular Solutions Pty Limited Prothèse de valvule cardiaque percutanée
US20050256566A1 (en) 2004-05-03 2005-11-17 Shlomo Gabbay Apparatus and method for improving ventricular function
US7374573B2 (en) 2004-05-03 2008-05-20 Shlomo Gabbay System and method for improving ventricular function
US20060122692A1 (en) 2004-05-10 2006-06-08 Ran Gilad Stent valve and method of using same
US20060008497A1 (en) 2004-07-09 2006-01-12 Shlomo Gabbay Implantable apparatus having improved biocompatibility and process of making the same
FR2874812B1 (fr) 2004-09-07 2007-06-15 Perouse Soc Par Actions Simpli Valve protheique interchangeable
EP2491891A3 (fr) 2004-10-02 2013-03-20 Endoheart AG Dispositifs de protection embolique et de réparation de la valvule mitrale
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
WO2006069094A1 (fr) 2004-12-20 2006-06-29 Cook Incorporated Grille de support intraluminale et dispositifs medicaux comprenant la grille de support
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
ITTO20050074A1 (it) 2005-02-10 2006-08-11 Sorin Biomedica Cardio Srl Protesi valvola cardiaca
US7331991B2 (en) 2005-02-25 2008-02-19 California Institute Of Technology Implantable small percutaneous valve and methods of delivery
SE531468C2 (sv) 2005-04-21 2009-04-14 Edwards Lifesciences Ag En anordning för styrning av blodflöde
EP3266414B1 (fr) 2005-05-12 2024-07-17 Covidien LP Système de pose d'implant avec orientation du port rx verrouillé
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US7799072B2 (en) 2005-05-20 2010-09-21 The Cleveland Clinic Foundation Apparatus and methods for repairing the function of a diseased valve and method for making same
US20090112309A1 (en) 2005-07-21 2009-04-30 The Florida International University Board Of Trustees Collapsible Heart Valve with Polymer Leaflets
US8790396B2 (en) 2005-07-27 2014-07-29 Medtronic 3F Therapeutics, Inc. Methods and systems for cardiac valve delivery
US20080269879A1 (en) 2005-07-27 2008-10-30 Rahul Dilip Sathe Implantable Prosthetic Vascular Valve
EP1933777B1 (fr) 2005-08-22 2017-06-14 Incept, LLC Stents evases et appareil pour leur utilisation
US20070067029A1 (en) 2005-09-16 2007-03-22 Shlomo Gabbay Support apparatus to facilitate implantation of cardiac prosthesis
US8092525B2 (en) 2005-10-26 2012-01-10 Cardiosolutions, Inc. Heart valve implant
WO2007062320A2 (fr) 2005-11-18 2007-05-31 Innovia, Llc Valvule cardiaque a trois feuillets
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
KR20080103510A (ko) 2005-12-22 2008-11-27 시메티스 에스에이 판막 교체를 위한 스텐트-판막 및 수술을 위한 연관된 방법및 시스템
EP2004095B1 (fr) 2006-03-28 2019-06-12 Medtronic, Inc. Valvule cardiaque prothétique constituée de matière péricardique et procédés de production de cette valvule
US7524331B2 (en) 2006-04-06 2009-04-28 Medtronic Vascular, Inc. Catheter delivered valve having a barrier to provide an enhanced seal
US20070244545A1 (en) 2006-04-14 2007-10-18 Medtronic Vascular, Inc. Prosthetic Conduit With Radiopaque Symmetry Indicators
AU2007255072A1 (en) 2006-05-30 2007-12-13 Cook Incorporated Artificial valve prosthesis
US20080097595A1 (en) 2006-08-22 2008-04-24 Shlomo Gabbay Intraventricular cardiac prosthesis
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US7534261B2 (en) 2006-10-02 2009-05-19 Edwards Lifesciences Corporation Sutureless heart valve attachment
EP2104470B1 (fr) 2006-12-06 2022-10-26 Medtronic Corevalve, LLC. Système et procédé d'acheminement transapical d'une valve auto-expansive ancrée dans un espace annulaire
FR2909857B1 (fr) 2006-12-14 2009-03-06 Perouse Soc Par Actions Simpli Endovalve.
US8236045B2 (en) 2006-12-22 2012-08-07 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method of making the same
WO2008101193A2 (fr) 2007-02-16 2008-08-21 Emory University Appareil et procédés de traitement de l'aorte
EP2155114B8 (fr) 2007-06-04 2020-05-20 St. Jude Medical, LLC Valvules cardiaques prothétiques
BRPI0812890A2 (pt) 2007-06-08 2017-05-23 St Jude Medical aparelho para fornecer instrumentação a um sistema circulatório de um paciente, e, aparelho para fechar uma abertura através de uma parede de um sistema circulatório de um paciente.
ES2475144T3 (es) 2007-06-26 2014-07-10 St. Jude Medical, Inc. Aparato para la implantación de válvulas prot�sicas de corazón replegables / expansibles
EP2192875B1 (fr) 2007-08-24 2012-05-02 St. Jude Medical, Inc. Valvules cardiaques aortiques prothétiques
US8425593B2 (en) 2007-09-26 2013-04-23 St. Jude Medical, Inc. Collapsible prosthetic heart valves
WO2009045331A1 (fr) 2007-09-28 2009-04-09 St. Jude Medical, Inc. Valvules cardiaques prothétiques repliables/déployables en deux temps et systèmes d'ancrage
WO2009045334A1 (fr) 2007-09-28 2009-04-09 St. Jude Medical, Inc. Valvules cardiaques prothétiques repliables/déployables dotées de caractéristiques de retenue des valves natives calcifiées
US20090138079A1 (en) 2007-10-10 2009-05-28 Vector Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
WO2009061389A2 (fr) 2007-11-05 2009-05-14 St. Jude Medical, Inc. Valvules prothétiques cardiaques rétractables/expansibles à montants de stent non extensibles et à caractéristiques de récupération
US20080114452A1 (en) 2007-11-14 2008-05-15 Shlomo Gabbay Prosthesis exhibiting post-implantation size change
AU2009205739B2 (en) 2008-01-16 2014-09-25 St. Jude Medical, Inc. Delivery and retrieval systems for collapsible/expandable prosthetic heart valves
CA2715448C (fr) 2008-02-25 2017-06-13 Medtronic Vascular Inc. Dispositifs de reduction infundibulaires
ATE554731T1 (de) 2008-05-16 2012-05-15 Sorin Biomedica Cardio Srl Atraumatische prothetische herzklappenprothese
CA3272239A1 (en) 2008-06-06 2025-10-28 Edwards Lifesciences Corporation Low profile transcatheter heart valve
DE202008009610U1 (de) 2008-07-17 2008-12-11 Nvt Ag Herzklappenprothesensystem
US20100217382A1 (en) 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
EP4119098A1 (fr) 2009-04-15 2023-01-18 Edwards Lifesciences CardiAQ LLC Implant vasculaire et système de distribution
US8845722B2 (en) 2009-08-03 2014-09-30 Shlomo Gabbay Heart valve prosthesis and method of implantation thereof
US9289291B2 (en) 2009-11-05 2016-03-22 The Trustees Of The University Of Pennsylvania Valve prosthesis
WO2011130579A1 (fr) * 2010-04-14 2011-10-20 Abbott Cardiovascular Systems Inc. Échafaudage intraluminal et son procédé de fabrication et d'utilisation
USD660432S1 (en) 2010-09-20 2012-05-22 St. Jude Medical, Inc. Commissure point
USD653341S1 (en) 2010-09-20 2012-01-31 St. Jude Medical, Inc. Surgical stent
USD653343S1 (en) 2010-09-20 2012-01-31 St. Jude Medical, Inc. Surgical cuff
USD684692S1 (en) 2010-09-20 2013-06-18 St. Jude Medical, Inc. Forked ends
USD654170S1 (en) 2010-09-20 2012-02-14 St. Jude Medical, Inc. Stent connections
USD660967S1 (en) 2010-09-20 2012-05-29 St. Jude Medical, Inc. Surgical stent
USD652927S1 (en) 2010-09-20 2012-01-24 St. Jude Medical, Inc. Surgical stent
USD654169S1 (en) 2010-09-20 2012-02-14 St. Jude Medical Inc. Forked ends
USD648854S1 (en) 2010-09-20 2011-11-15 St. Jude Medical, Inc. Commissure points
USD652926S1 (en) 2010-09-20 2012-01-24 St. Jude Medical, Inc. Forked end
USD653342S1 (en) 2010-09-20 2012-01-31 St. Jude Medical, Inc. Stent connections
USD660433S1 (en) 2010-09-20 2012-05-22 St. Jude Medical, Inc. Surgical stent assembly
US20140005776A1 (en) * 2012-06-29 2014-01-02 St. Jude Medical, Cardiology Division, Inc. Leaflet attachment for function in various shapes and sizes
US10004597B2 (en) * 2012-07-03 2018-06-26 St. Jude Medical, Cardiology Division, Inc. Stent and implantable valve incorporating same
EP3068346B1 (fr) * 2013-11-11 2021-03-03 Edwards Lifesciences CardiAQ LLC Procédé pour fabriquer un stent pour une prothèse de valve
EP3687451B1 (fr) * 2017-09-27 2023-12-13 Edwards Lifesciences Corporation Valvule prothétique à cadre extensible
EP3880127B1 (fr) * 2018-11-14 2024-02-21 Edwards Lifesciences Corporation Valvule cardiaque prothétique comprenant un élément support de commissure

Also Published As

Publication number Publication date
EP4480454A3 (fr) 2025-07-09
EP4003230B1 (fr) 2024-12-04
US20230270543A1 (en) 2023-08-31
US20210030536A1 (en) 2021-02-04
WO2021021482A1 (fr) 2021-02-04
US11672654B2 (en) 2023-06-13
EP4003230A1 (fr) 2022-06-01

Similar Documents

Publication Publication Date Title
US20230270543A1 (en) Alternate Stent CAF Design for TAVR
US12011350B2 (en) Rapid implant prosthetic heart valve system
US10842623B2 (en) Methods of implanting prosthetic heart valve using position markers
EP2129332B1 (fr) Valvules cardiaques prothétiques de remplacement
US20190201194A1 (en) Valve Assembly for Crimp Profile
US11284996B2 (en) Attachment of leaflets to prosthetic heart valve
US20230355381A1 (en) Detachable Cell Configuration for Valve in Valve
US11678980B2 (en) Fully-transseptal apical pad with pulley for tensioning
US12144727B2 (en) Tether attachment for mitral valve
US12138163B2 (en) Fully deployable and recapturable prosthetic heart valve

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN PUBLISHED

AC Divisional application: reference to earlier application

Ref document number: 4003230

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

RIC1 Information provided on ipc code assigned before grant

Ipc: A61F 2/24 20060101AFI20250605BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20251030