EP4520817A3 - In-vitro-herstellung von vorläuferzellen der medialen ganglionischen eminenz - Google Patents

In-vitro-herstellung von vorläuferzellen der medialen ganglionischen eminenz Download PDF

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Publication number
EP4520817A3
EP4520817A3 EP24216788.0A EP24216788A EP4520817A3 EP 4520817 A3 EP4520817 A3 EP 4520817A3 EP 24216788 A EP24216788 A EP 24216788A EP 4520817 A3 EP4520817 A3 EP 4520817A3
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EP
European Patent Office
Prior art keywords
precursor cells
vitro production
ganglionic eminence
mge
medial ganglionic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24216788.0A
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English (en)
French (fr)
Other versions
EP4520817A2 (de
Inventor
Cory R. NICHOLAS
John L. Rubenstein
Arnold R. KRIEGSTEIN
Arturo Alvarez-Buylla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
University of California Berkeley
University of California San Diego UCSD
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University of California
University of California Berkeley
University of California San Diego UCSD
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Publication date
Application filed by University of California, University of California Berkeley, University of California San Diego UCSD filed Critical University of California
Publication of EP4520817A2 publication Critical patent/EP4520817A2/de
Publication of EP4520817A3 publication Critical patent/EP4520817A3/de
Pending legal-status Critical Current

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP24216788.0A 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen der medialen ganglionischen eminenz Pending EP4520817A3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361783594P 2013-03-14 2013-03-14
EP19210467.7A EP3656849B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz
PCT/US2014/029734 WO2014153230A1 (en) 2013-03-14 2014-03-14 In vitro production of medial ganglionic eminence precursor cells
EP14769754.4A EP2970897B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP14769754.4A Division EP2970897B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz
EP19210467.7A Division EP3656849B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz

Publications (2)

Publication Number Publication Date
EP4520817A2 EP4520817A2 (de) 2025-03-12
EP4520817A3 true EP4520817A3 (de) 2025-06-25

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
EP19210467.7A Active EP3656849B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz
EP14769754.4A Active EP2970897B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz
EP24216788.0A Pending EP4520817A3 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen der medialen ganglionischen eminenz

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP19210467.7A Active EP3656849B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz
EP14769754.4A Active EP2970897B1 (de) 2013-03-14 2014-03-14 In-vitro-herstellung von vorläuferzellen für mediale ganglionische eminenz

Country Status (7)

Country Link
US (4) US10100279B2 (de)
EP (3) EP3656849B1 (de)
JP (5) JP2016520291A (de)
CN (2) CN105431522B (de)
AU (4) AU2014236150B2 (de)
CA (2) CA3143449C (de)
WO (1) WO2014153230A1 (de)

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