EP4577176A1 - Composition de nettoyage de la peau - Google Patents

Composition de nettoyage de la peau

Info

Publication number
EP4577176A1
EP4577176A1 EP23754761.7A EP23754761A EP4577176A1 EP 4577176 A1 EP4577176 A1 EP 4577176A1 EP 23754761 A EP23754761 A EP 23754761A EP 4577176 A1 EP4577176 A1 EP 4577176A1
Authority
EP
European Patent Office
Prior art keywords
composition
acid
amine
adduct
diamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23754761.7A
Other languages
German (de)
English (en)
Inventor
Vidula Iyer
Joseph Martin JANKOLOVITS
Rajkumar PERUMAL
Siva Rama Krishna PERALA
Maya Treesa Saji
Connor Patrick WALSH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever Global IP Ltd
Unilever IP Holdings BV
Original Assignee
Unilever Global IP Ltd
Unilever IP Holdings BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Global IP Ltd, Unilever IP Holdings BV filed Critical Unilever Global IP Ltd
Publication of EP4577176A1 publication Critical patent/EP4577176A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds

Definitions

  • the present invention relates to a skin cleansing composition.
  • the present invention relates to a skin cleansing composition that provides improved antimicrobial benefit.
  • Microbes e.g. bacteria, tend to colonize on surfaces e.g. human skin. Some of these microbes may trigger harmful effects if they enter the human system e.g. through cuts in the skin and through the act of ingestion. Therefore, there is a general desire to maintain hygiene by getting rid of such harm causing microbes. For example, people tend to wash hands with a skin cleansing composition from time to time to help maintain hygiene.
  • skin cleansing compositions e.g. a handwash or a bodywash composition
  • Such skin cleansing compositions are available in the form of a solid e.g. a bar such as soap bar; and in the form of a liquid e.g. a liquid handwash I bodywash composition.
  • antimicrobial benefit delivered by such skin cleansing compositions is delivered by one or more actives that may be present in such skin cleansing compositions.
  • skin cleansing composition comprising an antibacterial active e.g. triclosan, is known in the art.
  • the present invention relates to a skin cleansing composition
  • a skin cleansing composition comprising: i. from 1 to 85 wt% surfactant; and ii. from 0.1 to 15 wt% adduct of an amine or a diamine and an acid, iii. a pH adjuster; wherein the pH of the composition is from 4.0 to 10.5; wherein said acid is a mono or di carboxylic acid.
  • the present invention relates to a method of providing antimicrobial effect comprising the steps: a. applying to a surface the composition of the first aspect; and b. rinsing the surface within 5 minutes of carrying out step a.
  • the present invention relates to use of an adduct of an amine or a diamine and an acid in a composition having pH from 4.0 to 10.5 comprising a surfactant, wherein said acid is a mono or di carboxylic acid, for providing an antimicrobial effect.
  • amounts as used herein are expressed in percentage by weight based on total weight of the composition and may be abbreviated as “wt%”.
  • wt% weight based on total weight of the composition
  • the terms ‘antimicrobial benefit’ or ‘antimicrobial effect’ or ‘antimicrobial efficacy’ may be used interchangeably and they denote the same meaning.
  • ‘antimicrobial benefit’ or ‘antimicrobial effect’ or ‘antimicrobial efficacy’ means reduction in number of microbes e.g. bacteria, fungi and viruses.
  • the present invention relates to a skin cleansing composition according to the present invention (the composition) that comprises: i. from 1 to 85 wt% surfactant; and ii. from 0.1 to 15 wt% adduct of an amine or a diamine and an acid, and iii. a pH adjuster wherein the pH of the composition is from 4.0 to 10.5 wherein said acid is a mono or di carboxylic acid.
  • the amine is selected from alkyl substituted primary or secondary or tertiary amine wherein the alkyl group is straight or branched group formed of 2 to 8 carbon atoms and contains a hydroxy (-OH) substitution.
  • alkyl substituted primary or secondary or tertiary amine wherein the alkyl group is straight or branched group formed of 2 to 8 carbon atoms and contains a hydroxy (-OH) substitution, that may be used as the amine include monoethanolamine (MEA), diethanolamine (DEA), triethanolamine (TEA), monoisopropanolamine (MIPA), diisopropanolamine (DIPA), triisopropanolamine (TIPA) and mixtures thereof.
  • MEA, DEA and mixtures thereof are used as the amine.
  • amine or diamine so selected is a non-volatile amine.
  • the acid is selected from carboxylic acids having pKa in the range from 2.5 to 5.5.
  • the acid is preferably a mono or dicarboxylic acid.
  • the acid is selected from acetic acid (AA), glycolic acid, tartaric acid, salicylic acid, benzoic acid and mixtures thereof; and still more preferably, the acid is selected from acetic acid, glycolic acid and mixtures thereof.
  • An example of the adduct so formed includes an adduct formed of an amine e.g. monoethanolamine and an acid e.g. acetic acid, MEA-AA.
  • an adduct formed of an amine e.g. monoethanolamine and an acid e.g. acetic acid, MEA-AA is another examples of such adduct.
  • DEA-AA diethanolamine salt of acetic acid
  • TEA-AA triethanolamine salt of acetic acid
  • the composition comprises from 0.1 to 15 wt%, preferably from 0.5 to 13 wt%, more preferably from 1 to 11 wt%, even more preferably from 2 to 10 wt%, further more preferably from 3 to 7 wt% and still more preferably from 4 to 6 wt% adduct of an amine or a diamine and an acid.
  • pH adjuster preferably from 0.5 to 13 wt%, more preferably from 1 to 11 wt%, even more preferably from 2 to 10 wt%, further more preferably from 3 to 7 wt% and still more preferably from 4 to 6 wt% adduct of an amine or a diamine and an acid.
  • the composition of the invention includes a pH adjuster which is a water-soluble compound that adjusts the pH of the composition to the desired range.
  • pH adjuster which may be used are selected from one or more of sodium bicarbonate, potassium bicarbonate, sodium bisulphate, potassium bisulphate, lactic acid, tartaric acid, citric acid, or dilute solution of mineral acids like hydrochloric acid or sulphuric acid.
  • the pH adjuster is generally added to the composition to bring it to a pH less than 10.5 preferably less than 10.3. In the case where the composition is a soap bar, the pH adjuster is added to the soap composition prior to addition of the adduct.
  • the composition comprises surfactant.
  • the surfactant is selected from an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant and mixtures thereof. More preferably, the surfactant is selected from an anionic surfactant, an amphoteric surfactant and mixtures thereof.
  • a synthetic anionic surfactant is selected from alkyl sulfate (AS), alkyl ether sulfate (AES), alpha olefin sulfonate (AOS) and mixtures thereof.
  • AS alkyl sulfate
  • AES alkyl ether sulfate
  • AOS alpha olefin sulfonate
  • AS alkyl sulfate
  • AS alkyl sulfate
  • AES alkyl ether sulfate
  • AOS alpha olefin sulfonate
  • Ri is saturated or unsaturated Cs-Ci6, preferably C12-C14 alkyl chain; preferably, R1 is a saturated Cs-Ci6, more preferably a saturated C12-C14 alkyl chain;
  • R’ is ethylene; n is from 1 to 18; preferably from 1 to 15, more preferably from 1 to 10 and even more preferably from 1 to 5 and further more preferably from 1 to 3,
  • M + is a suitable cation which provides charge neutrality, preferably sodium, calcium, potassium, or magnesium, more preferably a sodium cation.
  • AES examples include sodium lauryl ether sulfate (SLES), sodium myristyl ether sulfate and sodium palmityl ether sulfate and mixtures thereof.
  • SLES sodium lauryl ether sulfate
  • Preferred AES is SLES having 1 to 3 ethylene oxide units per molecule. SLES having 1 to 2 ethylene oxide units per molecule is more preferred.
  • soap is used as the anionic surfactant in the composition.
  • soap so used is formed of fatty acids having carbon chain length from 8 to 18, more preferably from 12 to 16.
  • sodium or potassium salts of fatty acids having carbon chain length from 8 to 18 e.g. lauric acid, myristic acid, palmitic acid and oleic acid, either alone or as a mixture, may be used as anionic surfactant.
  • sodium laurate, sodium myristate, sodium palmitate, sodium oleate, potassium laurate, potassium myristate, potassium palmitate, potassium oleate and mixtures thereof may be used as an anionic surfactant.
  • Suitable cationic surfactants include those materials having the CTFA designations Quaternium-5, Quaternium-31 and Quaternium- 18. Mixtures of any of the foregoing materials may also be suitable.
  • a particularly useful cationic surfactant is cetyltrimethylammonium chloride, available commercially, for example as GENAMIN® CTAC.
  • Another particularly useful cationic surfactant is behenyltrimethylammonium chloride, available commercially, for example as GENAMIN® KDMP.
  • Yet another preferred cationic surfactant is stearamidopropyl dimethylamine.
  • the composition comprises from 1 to 85 wt% surfactant, preferably from 5 to 80 wt%, more preferably from 10 to 75 wt%, even more preferably from 15 to 70 wt%, yet more preferably from 25 to 66 wt%, still more preferably from 35 to 60 wt% and still further more preferably from 40 to 55 wt% surfactant.
  • the pH of the composition is in the range from 4.0 to 10.5, preferably from 4.5 to 10.3, even more preferably from 5.0 to 10.1, further more preferably from 5.5 to 10.0, still more preferably from 6.5 to 10.0 and yet more preferably from 8.0 to 10.0.
  • pH of the composition is most preferably 7.0 or 7.5.
  • the pH of the composition may be 9.5.
  • the pH of the composition may be adjusted using suitable pH adjusting agents e.g. sodium hydroxide and sodium bicarbonate.
  • pH of the composition is in the range 4.0 to 10.5 when measured before dilution or preferably after diluting the composition to 50% concentration, at 25 to 35°C.
  • pH of the composition is in the range from 4.0 to 10.5 when measured using 1 to 8% e.g. 8%, aqueous solution of the composition in demineralized water, at temperature 25 to 35°C.
  • the composition is in liquid form or in solid form. More preferably, the composition is in solid form e.g. a bar. Even more preferably, the composition is in the form of a soap bar.
  • the composition is preferably a liquid skin cleansing composition comprising: i. from 1 to 85 wt% surfactant; and ii. from 0.1 to 15 wt% adduct of an amine or a diamine and an acid, wherein the pH of the composition is from 4.0 to 10.5, preferably from 4.0 to 7.5; wherein said acid is a mono or di carboxylic acid
  • the composition is a solid skin cleansing composition comprising: i. from 1 to 85 wt% surfactant; and ii. from 0.1 to 15 wt% adduct of an amine or a diamine and an acid, wherein the pH of the composition is from 4.0 to 10.5, preferably from 8.0 to 10.1 ; wherein said acid is a mono or di carboxylic acid.
  • the composition is a soap bar composition comprising: i. from 40 to 85 wt% soap, ii. from 0.1 to 15 wt% adduct of an amine or a diamine and an acid, wherein the pH of the composition is from 4.0 to 10.5, preferably from 8.5 to 10.1 ; wherein said acid is a mono or di carboxylic acid
  • the composition comprises a structurant.
  • a structurant is selected from silica, talc, calcite, pumice, tricalcium phosphate, chalk, fullers earth, kaolin, starch, gums, colloidal silica, sodium polyacrylate, tetra alkyl and/or trialkyl aryl ammonium smectites, chemically modified magnesium aluminium silicate, organically modified montmorillonite clay, hydrated aluminium silicate, fumed silica, carboxyvinyl polymer, sodium carboxymethyl cellulose, ethylene glycol monostearate and mixtures thereof.
  • Talc is a magnesium silicate mineral material, with a sheet silicate structure and a composition of MgaSi4(OH)22 and may be available in the hydrated form. It has a plate-like morphology, and is essentially oleophilic/hydrophobic, i.e., it is wetted by oil rather than water.
  • Starch may be used directly or modified during the process of making the bar composition such that the starch becomes gelatinized, either partially or fully gelatinized.
  • Another suitable starch is pre-gelatinized which is starch that has been gelatinized before it is added as an ingredient in the present bar compositions.
  • Various forms are available that will gel at different temperatures, e.g., cold water dispersible starch.
  • the composition comprises structurants in an amount ranging from 1 to 50 wt%, more preferably from 3 to 45 wt%, even more preferably from 10 to 30 wt and further more preferably from 15 to 25 wt%.
  • the composition further comprises water soluble polymers.
  • such polymers are selected from polyvinyl alcohol, polyvinyl pyrrolidone, sodium carboxymethylcellulose, polyethylene glycol, methyl cellulose, hydroxypropyl methyl cellulose and mixtures thereof.
  • the composition comprises from 1 to 20 wt%, more preferably from 3 to 17 wt%, even more preferably from 5 to 15 wt%, further more preferably from 7 to 13 wt% and still more preferably from 9 to 12 wt% water soluble polymer.
  • Such polymer may be added in the composition mix or may be used to coat the composition.
  • the composition is in the form of a bar or a tablet, such polymers may form an outer water-soluble coating on such bars or tablets.
  • composition preferably comprises a polyhydric alcohol (also called polyol) or mixture of polyols.
  • polyol is a term used herein to designate a compound having multiple hydroxyl groups (at least two, preferably at least three) which is highly water soluble, preferably freely soluble, in water.
  • polyols are available including relatively low molecular weight short chain polyhydroxy compounds such as glycerol and propylene glycol; sugars such as sorbitol, manitol, sucrose and glucose; modified carbohydrates such as hydrolyzed starch, dextrin and maltodextrin, and polymeric synthetic polyols such as polyalkylene glycols, for example polyoxyethylene glycol (PEG) and polyoxypropylene glycol (PPG).
  • PEG polyoxyethylene glycol
  • PPG polyoxypropylene glycol
  • Especially preferred polyols are glycerol, sorbitol and their mixtures. Most preferred polyol is glycerol. If the composition is formulated as a bar then preferably it comprises from 0 to 8 wt%, more preferably from 1 to 7.5 wt%, even more preferably from 2 to 5 wt% polyol.
  • the composition further comprises an opacifier.
  • opacifiers include titanium dioxide, zinc oxide and the like.
  • An alternative opacifying agent is zinc stearate.
  • a preferred bar may additionally include up to 30 wt% benefit agents.
  • Preferred benefit agents include moisturizers, emollients, sunscreens and anti-ageing compounds. These agents may be added at an appropriate step during the process of making the composition.
  • composition may further comprise one or more of the following ingredients:
  • the composition may preferably further comprise a skin-lightening agent selected from ammonium lactate, arbutin, azelaic acid, kojic acid, butyl hydroxy anisole, butyl hydroxy toluene, citrate esters, 3 diphenyl propane derivatives, ellagic acid, gluco pyranosyl-1 -ascorbate, gluconic acid, glycolic acid, hydroquinone, 4 hydroxyanisole, linoleic acid, magnesium ascorbyl phosphate, 2,4 resorcinol derivatives, 3,5 resorcinol derivatives, vitamins like vitamin B6, vitamin B12, vitamin C, vitamin A, resorcinol derivatives and mixtures thereof.
  • a skin-lightening agent selected from ammonium lactate, arbutin, azelaic acid, kojic acid, butyl hydroxy anisole, butyl hydroxy toluene, citrate esters, 3 diphenyl propane derivatives, ella
  • composition is formulated in the form of solid e.g. a bar such as soap bar, then it preferably comprises water in an amount from 10 to 20 wt%, more preferably from 14 to 18 wt%.
  • the composition if the composition is formulated in the form of a liquid, then the composition preferably comprises from 40 to 90 wt% water, more preferably 60 to 85 wt% water.
  • the composition may preferably further comprise preservatives to protect the composition against the growth of potentially harmful microorganisms.
  • preservatives include hydantoin derivatives, propionate salts, a variety of quaternary ammonium compounds, phenoxyethanol, imidazolidinyl urea, sodium dehydroacetate and benzyl alcohol.
  • Preservatives are preferably used in amounts ranging from 0.01 wt% to 2 wt%.
  • Diluents other than water can include liquid or solid emollients, solvents, humectants, thickeners and powders. Examples of each of these types of vehicles which can be used singly or as mixtures of one or more vehicles, are as follows:
  • Emollients such as stearyl alcohol, glyceryl monoricinoleate, mink oil, cetyl alcohol, isopropyl isostearate, stearic acid, isobutyl palmitate, isocetyl stearate, oleyl alcohol, isopropyl laurate, hexyl laurate, decyl oleate, octadecan-2-ol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, cetyl palmitate, silicone oils such as dimethylpolysiloxane, di-n-butyl sebacate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, butyl stearate, polyethylene glycol, triethylene glycol, lanolin, cocoa butter, corn oil, cotton seed oil, olive oil, palm kernel oil, rape seed oil, safflower seed oil, evening primrose oil, soybean oil, sunflower
  • the composition preferably comprises other optional ingredients like anti-oxidants, perfumes, polymers, chelating agents, colourants, deodorants, dyes, emollients, moisturizers, enzymes, foam boosters, lathering agents, skin conditioners, pH adjusters and stabilizers may be added in suitable amounts.
  • these ingredients are added after the saponification step.
  • Sodium metabisulphite, ethylene diamine tetra acetic acid (EDTA), borax or ethylene hydroxy diphosphonic acid (EHDP) are preferably added to the formulation.
  • Such ingredients may be present in an amount from 0 to 7 wt%, more preferably from 1 to 5 wt% and even more preferably from 2 to 4 wt% in the composition.
  • the present invention relates to a method of providing antimicrobial benefit comprising the steps: a. applying to a surface the composition according to the first aspect; and b. rinsing the surface within 5 minutes of carrying out the step a.
  • Step a involves applying the composition of the first aspect on to a surface.
  • the surface is preferably an inanimate or animate surface. More preferably, the surface is an animate surface e.g. human skin.
  • ‘Skin’ as used herein, preferably means to include skin on any part of the body e.g. face, neck, chest, back, arms, underarms, hands, legs, buttocks and scalp.
  • Step a is preferably carried out where a user applies the composition of the first aspect, on to a surface along with water in an amount sufficient to create lather.
  • the method comprises an additional step, step b, where the surface on to which the composition was applied, is rinsed with water to remove the composition from the surface.
  • step (b) is carried out within less than 5 minutes, more preferably within less than 3 minutes, even more preferably within less than 1 minute and furthermore preferably within less than 35 seconds e.g. 10 to 30 seconds, after step a.
  • antimicrobial benefit is obtained, i.e. microbes e.g. bacteria, are reduced from the surface on to which the composition was so applied.
  • the method is non-therapeutic and/or cosmetic in nature.
  • the present invention relates to use of an adduct of an amine or a diamine and an acid in a composition comprising a surfactant; and pH in the range from 4.0 to 10.5, for providing antimicrobial effect.
  • the present invention relates to use of MEA-AA or DEA-AA or TEA-AA in a composition comprising a surfactant and pH in the range 4.0 to 10.5 for providing antimicrobial effect.
  • the use is non-therapeutic and/or cosmetic in nature.
  • the present invention relates to a process of manufacturing a skin cleansing composition according to the present invention.
  • the composition in the form of a solid e.g. soap bar may be prepared using the process described below:
  • An adduct is a product of addition reaction.
  • the adduct in the present invention is preferably prepared by the following process.
  • the amine is taken in a flask equipped with a magnetic bead, a reflux condenser and dropping funnel.
  • the acid is then added drop wise to the amine solution over a period of about one hour under vigorous mixing condition. This is then continuously mixed for an additional about 8 hours to complete the reaction.
  • a 50% amine solution is taken in water in a flask and 50% acid solution is added in portions over about an hour which is then mixed for a further about 8 hours.
  • the reaction mixture as such or after extraction with organic solvent is then used in making the composition as per the invention.
  • Additional ten-fold dilutions were prepared by transferring 1 mL aliquots into 9 mL of neutralizer (1 O’ 2 , 10’ 3 , 10' 4 and 10' 5 ). 1.0 mL aliquots of each dilution from 10' 1 to10 -5 were plated using TSA in duplicate using pour plate technique. The plates were incubated as per given incubation conditions.
  • Soap noodles shown in table 1 above were used to prepare final soap bars (as shown in table 2 below) using the process as described hereinabove.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention concerne une composition de nettoyage de la peau, en particulier une composition de nettoyage de la peau qui offre un avantage antimicrobien amélioré. La composition de nettoyage de la peau comprend un tensioactif, de préférence un savon et un adduit d'une amine ou d'une diamine et d'un acide ; et elle présente un pH compris dans la plage de 4,0 à 10,5, ledit acide étant un acide mono- ou di-carboxylique.
EP23754761.7A 2022-08-23 2023-08-09 Composition de nettoyage de la peau Pending EP4577176A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22191591 2022-08-23
PCT/EP2023/072023 WO2024041888A1 (fr) 2022-08-23 2023-08-09 Composition de nettoyage de la peau

Publications (1)

Publication Number Publication Date
EP4577176A1 true EP4577176A1 (fr) 2025-07-02

Family

ID=83049853

Family Applications (1)

Application Number Title Priority Date Filing Date
EP23754761.7A Pending EP4577176A1 (fr) 2022-08-23 2023-08-09 Composition de nettoyage de la peau

Country Status (4)

Country Link
EP (1) EP4577176A1 (fr)
CN (1) CN119855577A (fr)
MX (1) MX2025002153A (fr)
WO (1) WO2024041888A1 (fr)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2291634A (en) * 1942-08-04 Thickening of solutions
BE628201A (fr) * 1962-02-09
CA1290316C (fr) * 1985-06-27 1991-10-08 Alain Louis Pierre Lenack Fluides aqueux
GB2243614B (en) * 1990-05-04 1993-05-12 Procter & Gamble Beta-phase soap bars made with soap derived from high titer and low iodine value fatty feedstock
US20080026974A1 (en) * 2006-07-27 2008-01-31 Barnhart Ronald A Antimicrobial hand wash
CN104055782A (zh) * 2013-03-19 2014-09-24 孙占全 皮肤抑菌滋养乳膏
CN109528562A (zh) * 2018-12-28 2019-03-29 中山市天图精细化工有限公司 一种个人护理用的活氧拉丝洁面慕斯及其制备方法

Also Published As

Publication number Publication date
WO2024041888A1 (fr) 2024-02-29
CN119855577A (zh) 2025-04-18
MX2025002153A (es) 2025-04-02

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