EP4702152A1 - Temperaturempfindliches baculovirus-expressionsvektorsystem zur herstellung von baculovirus-virionfreien biopharmazeutika - Google Patents

Temperaturempfindliches baculovirus-expressionsvektorsystem zur herstellung von baculovirus-virionfreien biopharmazeutika

Info

Publication number
EP4702152A1
EP4702152A1 EP24725026.9A EP24725026A EP4702152A1 EP 4702152 A1 EP4702152 A1 EP 4702152A1 EP 24725026 A EP24725026 A EP 24725026A EP 4702152 A1 EP4702152 A1 EP 4702152A1
Authority
EP
European Patent Office
Prior art keywords
baculovirus
gene
temperature
production
biopharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24725026.9A
Other languages
English (en)
French (fr)
Inventor
Linda VAN OOSTEN
Gorben Peter Pijlman
Jort Jan ALTENBURG
Derk Egbert MARTENS
Monique Maria VAN OERS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wageningen Universiteit
Original Assignee
Wageningen Universiteit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wageningen Universiteit filed Critical Wageningen Universiteit
Publication of EP4702152A1 publication Critical patent/EP4702152A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP24725026.9A 2023-04-26 2024-04-26 Temperaturempfindliches baculovirus-expressionsvektorsystem zur herstellung von baculovirus-virionfreien biopharmazeutika Pending EP4702152A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23170183 2023-04-26
PCT/NL2024/050220 WO2024225904A1 (en) 2023-04-26 2024-04-26 Temperature-sensitive baculovirus expression vector system for the production of baculovirus virion-free biopharmaceuticals

Publications (1)

Publication Number Publication Date
EP4702152A1 true EP4702152A1 (de) 2026-03-04

Family

ID=86282323

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24725026.9A Pending EP4702152A1 (de) 2023-04-26 2024-04-26 Temperaturempfindliches baculovirus-expressionsvektorsystem zur herstellung von baculovirus-virionfreien biopharmazeutika

Country Status (2)

Country Link
EP (1) EP4702152A1 (de)
WO (1) WO2024225904A1 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090584A (en) * 1997-08-21 2000-07-18 University Technologies International Inc. Baculovirus artificial chromosomes and methods of use

Also Published As

Publication number Publication date
WO2024225904A1 (en) 2024-10-31

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