EP4704775A2 - Dispositif d'administration thérapeutique de réticulation du collagène cornéen - Google Patents

Dispositif d'administration thérapeutique de réticulation du collagène cornéen

Info

Publication number
EP4704775A2
EP4704775A2 EP24800698.3A EP24800698A EP4704775A2 EP 4704775 A2 EP4704775 A2 EP 4704775A2 EP 24800698 A EP24800698 A EP 24800698A EP 4704775 A2 EP4704775 A2 EP 4704775A2
Authority
EP
European Patent Office
Prior art keywords
epithelial
spikes
body portion
cornea
corneal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24800698.3A
Other languages
German (de)
English (en)
Inventor
Mark Lobanoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP4704775A2 publication Critical patent/EP4704775A2/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Prostheses (AREA)

Abstract

Dispositif conçu pour aider à la réalisation de procédures de réticulation du collagène cornéen. Le dispositif comprend une partie corps avec un côté supérieur et un côté inférieur, ce dernier présentant une partie concave conçue pour être placée sur une couche épithéliale cornéenne à des fins de distribution de pression uniforme. Le dispositif incorpore une pluralité de pointes épithéliales hautes de 50 microns positionnées sur le côté inférieur, visant à créer des micro-perforations dans la couche épithéliale cornéenne lorsqu'une pression est appliquée au niveau du côté supérieur du dispositif. En créant ces micro-perforations, le dispositif facilite une pénétration améliorée d'agents thérapeutiques, tels que la riboflavine, dans le cadre de procédures de réticulation du collagène cornéen. Le dispositif, à base de silicone et présentant la forme d'une lentille de contact, représente une application innovante de la technologie des micro-aiguilles dans le domaine de l'ophtalmologie, et résout des limitations majeures associées à des procédés classiques d'administration de médicament à l'œil.
EP24800698.3A 2023-05-03 2024-05-03 Dispositif d'administration thérapeutique de réticulation du collagène cornéen Pending EP4704775A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363463738P 2023-05-03 2023-05-03
US202363538641P 2023-09-15 2023-09-15
PCT/US2024/027784 WO2024229408A2 (fr) 2023-05-03 2024-05-03 Dispositif d'administration thérapeutique de réticulation du collagène cornéen

Publications (1)

Publication Number Publication Date
EP4704775A2 true EP4704775A2 (fr) 2026-03-11

Family

ID=93333421

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24800698.3A Pending EP4704775A2 (fr) 2023-05-03 2024-05-03 Dispositif d'administration thérapeutique de réticulation du collagène cornéen

Country Status (5)

Country Link
EP (1) EP4704775A2 (fr)
KR (1) KR20260008115A (fr)
CN (1) CN121463936A (fr)
MX (1) MX2025013086A (fr)
WO (1) WO2024229408A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121015534A (zh) * 2025-08-25 2025-11-28 首都医科大学附属北京同仁医院 一种用于紫外光巩膜交联的可溶性微针贴片及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7918814B2 (en) * 2006-05-02 2011-04-05 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
EP3496681A4 (fr) * 2016-08-08 2020-07-22 Avedro, Inc. Systèmes et procédés de traitements d'un il par réticulation
US12115103B2 (en) * 2020-10-16 2024-10-15 Mark Lobanoff Silicone device for corneal cross-linking
WO2023059933A1 (fr) * 2021-10-08 2023-04-13 Purdue Research Foundation Dispositif d'administration de médicament oculaire et procédés associés

Also Published As

Publication number Publication date
WO2024229408A2 (fr) 2024-11-07
KR20260008115A (ko) 2026-01-15
MX2025013086A (es) 2026-04-01
WO2024229408A3 (fr) 2025-04-03
CN121463936A (zh) 2026-02-03

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