EP4704831A2 - Substituierte pyrimidinon- und azapyrimidinonverbindungen, zusammensetzungen und verwendungen davon - Google Patents

Substituierte pyrimidinon- und azapyrimidinonverbindungen, zusammensetzungen und verwendungen davon

Info

Publication number
EP4704831A2
EP4704831A2 EP24798058.4A EP24798058A EP4704831A2 EP 4704831 A2 EP4704831 A2 EP 4704831A2 EP 24798058 A EP24798058 A EP 24798058A EP 4704831 A2 EP4704831 A2 EP 4704831A2
Authority
EP
European Patent Office
Prior art keywords
cov
compound
coronavirus
patient
present disclosure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24798058.4A
Other languages
English (en)
French (fr)
Inventor
Kelvin Cooper
Steven A. Kates
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lakewood Amedex Inc
Original Assignee
Lakewood Amedex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lakewood Amedex Inc filed Critical Lakewood Amedex Inc
Publication of EP4704831A2 publication Critical patent/EP4704831A2/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP24798058.4A 2023-04-26 2024-04-26 Substituierte pyrimidinon- und azapyrimidinonverbindungen, zusammensetzungen und verwendungen davon Pending EP4704831A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363498460P 2023-04-26 2023-04-26
PCT/US2024/026526 WO2024226983A2 (en) 2023-04-26 2024-04-26 Substituted pyrimidinone and azapyrimidinone compounds, compositions, and uses thereof

Publications (1)

Publication Number Publication Date
EP4704831A2 true EP4704831A2 (de) 2026-03-11

Family

ID=93257399

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24798058.4A Pending EP4704831A2 (de) 2023-04-26 2024-04-26 Substituierte pyrimidinon- und azapyrimidinonverbindungen, zusammensetzungen und verwendungen davon

Country Status (3)

Country Link
EP (1) EP4704831A2 (de)
CN (1) CN121358474A (de)
WO (1) WO2024226983A2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009030254A1 (en) * 2007-09-04 2009-03-12 Curevac Gmbh Complexes of rna and cationic peptides for transfection and for immunostimulation
EP2917341B1 (de) * 2012-11-08 2017-09-27 Centre National de la Recherche Scientifique (CNRS) Neue mutante phosphodeoxyribosyltransferase-enzyme und verwendungen davon
WO2015143712A1 (en) * 2014-03-28 2015-10-01 Merck Sharp & Dohme Corp. 4'-substituted nucleoside reverse transcriptase inhibitors
WO2023207942A1 (zh) * 2022-04-25 2023-11-02 北京沐华生物科技有限责任公司 用于治疗或预防冠状病毒感染的核苷类药物及其用途

Also Published As

Publication number Publication date
WO2024226983A3 (en) 2025-01-23
CN121358474A (zh) 2026-01-16
WO2024226983A2 (en) 2024-10-31

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