EP4704976A1 - Dispositifs d'administration de composés anti-vih - Google Patents

Dispositifs d'administration de composés anti-vih

Info

Publication number
EP4704976A1
EP4704976A1 EP24797745.7A EP24797745A EP4704976A1 EP 4704976 A1 EP4704976 A1 EP 4704976A1 EP 24797745 A EP24797745 A EP 24797745A EP 4704976 A1 EP4704976 A1 EP 4704976A1
Authority
EP
European Patent Office
Prior art keywords
drug delivery
patch
nrtti
subject
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24797745.7A
Other languages
German (de)
English (en)
Inventor
Ashley R. Johnson
Stephanie Elizabeth BARRETT
Angela M. Wagner
Nathan D. RUDD
Ryan W. LUTZ
Jay A. Grobler
Adam T. Procopio
Ryan F. Donnelly
Qonita Kurnia ANJANI
Akmal Hidayat BIN SABRI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme LLC
Publication of EP4704976A1 publication Critical patent/EP4704976A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dispositifs d'administration de médicament comprenant un timbre à micro-aiguilles, ou un timbre à microréseau, contenant un inhibiteur de la translocation de transcriptase inverse de nucléoside anti-VIH (par exemple, islatravir). Les dispositifs peuvent être appliqués à un sujet pour prévenir ou traiter une infection par le VIH.
EP24797745.7A 2023-04-28 2024-04-23 Dispositifs d'administration de composés anti-vih Pending EP4704976A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363498907P 2023-04-28 2023-04-28
PCT/US2024/025807 WO2024226485A1 (fr) 2023-04-28 2024-04-23 Dispositifs d'administration de composés anti-vih

Publications (1)

Publication Number Publication Date
EP4704976A1 true EP4704976A1 (fr) 2026-03-11

Family

ID=93257249

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24797745.7A Pending EP4704976A1 (fr) 2023-04-28 2024-04-23 Dispositifs d'administration de composés anti-vih

Country Status (2)

Country Link
EP (1) EP4704976A1 (fr)
WO (1) WO2024226485A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017066768A1 (fr) * 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Administration de médicament bioactif multicomposant et libération contrôlée dans la peau par des dispositifs de matrice de micro-aiguilles
AU2021268584A1 (en) * 2020-05-05 2022-12-01 Merck Sharp & Dohme Llc Drug delivery system for the delivery of antiviral agents and contraceptives
MX2023009445A (es) * 2021-02-16 2023-08-25 Merck Sharp & Dohme Llc Compuestos de heterociclos tetraciclicos utiles como inhibidores de la integrasa del vih.

Also Published As

Publication number Publication date
WO2024226485A1 (fr) 2024-10-31

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