EP4705443A1 - Genetisch modifizierte hefe und fermentationsverfahren zur herstellung von arabit - Google Patents

Genetisch modifizierte hefe und fermentationsverfahren zur herstellung von arabit

Info

Publication number
EP4705443A1
EP4705443A1 EP24730136.9A EP24730136A EP4705443A1 EP 4705443 A1 EP4705443 A1 EP 4705443A1 EP 24730136 A EP24730136 A EP 24730136A EP 4705443 A1 EP4705443 A1 EP 4705443A1
Authority
EP
European Patent Office
Prior art keywords
seq
promoter
enzyme
yeast cell
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24730136.9A
Other languages
English (en)
French (fr)
Inventor
Peter Alan JAUERT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Publication of EP4705443A1 publication Critical patent/EP4705443A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/0125—D-Arabinitol 2-dehydrogenase (1.1.1.250)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01301—D-Arabitol-phosphate dehydrogenase (1.1.1.301)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/0305—Sorbitol-6-phosphatase (3.1.3.50)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP24730136.9A 2023-05-04 2024-05-02 Genetisch modifizierte hefe und fermentationsverfahren zur herstellung von arabit Pending EP4705443A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363499991P 2023-05-04 2023-05-04
PCT/US2024/027355 WO2024229190A1 (en) 2023-05-04 2024-05-02 Genetically modified yeast and fermentation processes for the production of arabitol

Publications (1)

Publication Number Publication Date
EP4705443A1 true EP4705443A1 (de) 2026-03-11

Family

ID=91334622

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24730136.9A Pending EP4705443A1 (de) 2023-05-04 2024-05-02 Genetisch modifizierte hefe und fermentationsverfahren zur herstellung von arabit

Country Status (3)

Country Link
EP (1) EP4705443A1 (de)
CN (1) CN121175415A (de)
WO (1) WO2024229190A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9929128D0 (en) 1999-12-10 2000-02-02 Cerestar Holding Bv Process for producing and recovering Erythritol from culture medium containing the same
US20210002620A1 (en) * 2019-04-19 2021-01-07 The Trustees Of Princeton University Methods and Materials for Producing Polyols and Electron Rich Compounds
EP4522730A1 (de) * 2022-05-09 2025-03-19 Cargill, Incorporated Genetisch modifizierte hefe und fermentationsverfahren zur herstellung von arabit
WO2023220547A1 (en) * 2022-05-09 2023-11-16 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of polyols
WO2023220546A1 (en) * 2022-05-09 2023-11-16 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of arabitol

Also Published As

Publication number Publication date
CN121175415A (zh) 2025-12-19
WO2024229190A1 (en) 2024-11-07

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