EP4705445A2 - Séquences de ribozymes pour le traitement d'arn - Google Patents

Séquences de ribozymes pour le traitement d'arn

Info

Publication number
EP4705445A2
EP4705445A2 EP24800422.8A EP24800422A EP4705445A2 EP 4705445 A2 EP4705445 A2 EP 4705445A2 EP 24800422 A EP24800422 A EP 24800422A EP 4705445 A2 EP4705445 A2 EP 4705445A2
Authority
EP
European Patent Office
Prior art keywords
rna
cell
molecule
ribozyme
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24800422.8A
Other languages
German (de)
English (en)
Inventor
Brianne CONLON
Scott A. Bevan
Tomàs CERMÀK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inari Agriculture Technology Inc
Original Assignee
Inari Agriculture Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inari Agriculture Technology Inc filed Critical Inari Agriculture Technology Inc
Publication of EP4705445A2 publication Critical patent/EP4705445A2/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des molécules d'ADN contenant des ribozymes qui fournissent des ARN produits ayant des terminaisons 3' définies ainsi que des cellules contenant les molécules d'ADN et des procédés associés.
EP24800422.8A 2023-05-02 2024-04-30 Séquences de ribozymes pour le traitement d'arn Pending EP4705445A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363499656P 2023-05-02 2023-05-02
PCT/US2024/026941 WO2024228975A2 (fr) 2023-05-02 2024-04-30 Séquences de ribozymes pour le traitement d'arn

Publications (1)

Publication Number Publication Date
EP4705445A2 true EP4705445A2 (fr) 2026-03-11

Family

ID=93333285

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24800422.8A Pending EP4705445A2 (fr) 2023-05-02 2024-04-30 Séquences de ribozymes pour le traitement d'arn

Country Status (2)

Country Link
EP (1) EP4705445A2 (fr)
WO (1) WO2024228975A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020097445A1 (fr) * 2018-11-09 2020-05-14 Inari Agriculture, Inc. Nucléases guidées par arn et protéines de liaison à l'adn
EP3980533A1 (fr) * 2019-06-07 2022-04-13 Scribe Therapeutics Inc. Systèmes casx modifiés
WO2022272293A1 (fr) * 2021-06-23 2022-12-29 The Board Of Trustees Of The Leland Stanford Junior University Compositions et procédés pour la production efficace de rétrons et l'édition génétique

Also Published As

Publication number Publication date
WO2024228975A2 (fr) 2024-11-07
WO2024228975A3 (fr) 2024-12-12

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