EP4705474A2 - Arn satellite de tymovirales artificiels - Google Patents

Arn satellite de tymovirales artificiels

Info

Publication number
EP4705474A2
EP4705474A2 EP24729531.4A EP24729531A EP4705474A2 EP 4705474 A2 EP4705474 A2 EP 4705474A2 EP 24729531 A EP24729531 A EP 24729531A EP 4705474 A2 EP4705474 A2 EP 4705474A2
Authority
EP
European Patent Office
Prior art keywords
rna
virus
hrv
sequence
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24729531.4A
Other languages
German (de)
English (en)
Inventor
David George BLUMSACK
Fu Chyun CHU
Elizabeth Jane Antonelli DENNIS
Jean-Pierre Baptiste Séhi GLOUZON
Mehmet Ali HALAC
Yumeng HAO
Arjun Devang KHAKHAR
Kevin KLICKI
James Michael KREMER
Jayashree Kumar
Katherine Michelle LATOURRETTE
Barry Andrew Martin
Shankar Raj PANT
Derek Thomas ROTHENHEBER
Michka Gabrielle SHARPE
Aditya Sushil Kumar SINGH
Arjun Subedi
Phu Tri Tran
Paveena VICHYAVICHIEN
Reid Evan William WARSABA
Kaixi ZHAO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flagship Pioneering Innovations VII Inc
Original Assignee
Flagship Pioneering Innovations VII Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flagship Pioneering Innovations VII Inc filed Critical Flagship Pioneering Innovations VII Inc
Publication of EP4705474A2 publication Critical patent/EP4705474A2/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention divulgue des molécules d'ARN satellite de Tymovirales synthétiques et des particules satellites les contenant. L'invention concerne également des molécules d'ARN satellite de Tymovirales synthétiques qui contiennent des amplicons du virus à ARN hétérologue interne (HRV). Sont également divulguées des méthodes d'utilisation des molécules d'ARN satellite de Tymovirales et des particules satellites les contenant pour modifier les phénotypes des plantes, améliorer la résistance des plantes au stress et améliorer la résistance des plantes aux parasites et aux pathogènes.
EP24729531.4A 2023-05-03 2024-05-03 Arn satellite de tymovirales artificiels Pending EP4705474A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363499758P 2023-05-03 2023-05-03
PCT/US2024/027687 WO2024229359A2 (fr) 2023-05-03 2024-05-03 Arn satellite de tymovirales artificiels

Publications (1)

Publication Number Publication Date
EP4705474A2 true EP4705474A2 (fr) 2026-03-11

Family

ID=91302563

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24729531.4A Pending EP4705474A2 (fr) 2023-05-03 2024-05-03 Arn satellite de tymovirales artificiels

Country Status (4)

Country Link
EP (1) EP4705474A2 (fr)
CN (1) CN121844053A (fr)
AR (1) AR132588A1 (fr)
WO (1) WO2024229359A2 (fr)

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
DE3585275D1 (de) 1984-12-10 1992-03-05 Monsanto Co Einsetzung des bacillus thuringiensis kristallproteingens in pflanzen kolonisierende mikroorganismen und deren verwendung.
US6774283B1 (en) 1985-07-29 2004-08-10 Calgene Llc Molecular farming
US6617496B1 (en) 1985-10-16 2003-09-09 Monsanto Company Effecting virus resistance in plants through the use of negative strand RNAs
US6608241B1 (en) 1985-10-29 2003-08-19 Monsanto Technology Llc Protection of plants against viral infection
US5322938A (en) 1987-01-13 1994-06-21 Monsanto Company DNA sequence for enhancing the efficiency of transcription
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
US5229114A (en) 1987-08-20 1993-07-20 The United States Of America As Represented By The Secretary Of Agriculture Approaches useful for the control of root nodulation of leguminous plants
US5597718A (en) 1988-10-04 1997-01-28 Agracetus Genetically engineering cotton plants for altered fiber
EP1103616A3 (fr) 1989-02-24 2001-06-27 Monsanto Company Gènes synthétiques de plantes et méthode pour leur préparation
US5689041A (en) 1989-08-10 1997-11-18 Plant Gentic Systems N.V. Plants modified with barstar for fertility restoration
US5641876A (en) 1990-01-05 1997-06-24 Cornell Research Foundation, Inc. Rice actin gene and promoter
US6426447B1 (en) 1990-11-14 2002-07-30 Monsanto Technology Llc Plant seed oils
US5543576A (en) 1990-03-23 1996-08-06 Mogen International Production of enzymes in seeds and their use
US5969214A (en) 1990-06-11 1999-10-19 Calgene, Inc. Glycogen biosynthetic enzymes in plants
ATE212670T1 (de) 1990-06-18 2002-02-15 Monsanto Technology Llc Erhöhter stärkegehalt in pflanzen
US5498830A (en) 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
EP0536330B1 (fr) 1990-06-25 2002-02-27 Monsanto Technology LLC Plantes tolerant le glyphosate
USRE38446E1 (en) 1990-07-20 2004-02-24 Calgene, Llc. Sucrose phosphate synthase (SPS), its process for preparation its cDNA, and utilization of cDNA to modify the expression of SPS in plant cells
US6483008B1 (en) 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
US5866775A (en) 1990-09-28 1999-02-02 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases
CA2096637A1 (fr) 1990-12-26 1992-06-27 Harry J. Klee Regulation de la maturation des fruits et de la senescence chez les plantes
US5304730A (en) 1991-09-03 1994-04-19 Monsanto Company Virus resistant plants and method therefore
US5763245A (en) 1991-09-23 1998-06-09 Monsanto Company Method of controlling insects
US6015940A (en) 1992-04-07 2000-01-18 Monsanto Company Virus resistant potato plants
US5850023A (en) 1992-11-30 1998-12-15 Monsanto Company Modified plant viral replicase genes
US6011199A (en) 1992-12-15 2000-01-04 Commonwealth Scientific Method for producing fruiting plants with improved fruit flavour
US6013864A (en) 1993-02-03 2000-01-11 Monsanto Company Plants resistant to infection by luteoviruses
US5322687A (en) 1993-07-29 1994-06-21 Ecogen Inc. Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects
AU7925094A (en) 1993-09-30 1995-04-18 Agracetus, Inc. Transgenic cotton plants producing heterologous peroxidase
EP0733116A1 (fr) 1993-11-24 1996-09-25 Monsanto Company Procede de limitation d'agents pathogenes chez les vegetaux
US5689052A (en) 1993-12-22 1997-11-18 Monsanto Company Synthetic DNA sequences having enhanced expression in monocotyledonous plants and method for preparation thereof
US6828475B1 (en) 1994-06-23 2004-12-07 Calgene Llc Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-CoA metabolism
US6080560A (en) 1994-07-25 2000-06-27 Monsanto Company Method for producing antibodies in plant cells
US6140075A (en) 1994-07-25 2000-10-31 Monsanto Company Method for producing antibodies and protein toxins in plant cells
US5750876A (en) 1994-07-28 1998-05-12 Monsanto Company Isoamylase gene, compositions containing it, and methods of using isoamylases
US5716837A (en) 1995-02-10 1998-02-10 Monsanto Company Expression of sucrose phosphorylase in plants
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US6946588B2 (en) 1996-03-13 2005-09-20 Monsanto Technology Llc Nucleic acid encoding a modified threonine deaminase and methods of use
US6091002A (en) 1996-03-13 2000-07-18 Monsanto Company Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants
US5773696A (en) 1996-03-29 1998-06-30 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
US6166292A (en) 1996-04-26 2000-12-26 Ajinomoto Co., Inc. Raffinose synthetase gene, method of producing raffinose and transgenic plant
US5985605A (en) 1996-06-14 1999-11-16 Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada DNA sequences encoding phytases of ruminal microorganisms
US5998700A (en) 1996-07-02 1999-12-07 The Board Of Trustees Of Southern Illinois University Plants containing a bacterial Gdha gene and methods of use thereof
US5750848A (en) 1996-08-13 1998-05-12 Monsanto Company DNA sequence useful for the production of polyhydroxyalkanoates
US6063756A (en) 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
US6093695A (en) 1996-09-26 2000-07-25 Monsanto Company Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and ctenocephalides SPP
WO1998018949A2 (fr) 1996-10-29 1998-05-07 Calgene Llc Cellulose synthase vegetale et sequences promotrices
EP0942985B1 (fr) 1996-11-20 2004-09-15 Monsanto Technology LLC Endotoxines delta a large spectre
US6017534A (en) 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
US6713063B1 (en) 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
US5942664A (en) 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
WO1998027104A1 (fr) 1996-12-19 1998-06-25 Yale University Polynucleotides allosteres bioreactifs
US6171640B1 (en) 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6372211B1 (en) 1997-04-21 2002-04-16 Monsanto Technolgy Llc Methods and compositions for controlling insects
US6380466B1 (en) 1997-05-08 2002-04-30 Calgene Llc Production of improved rapeseed exhibiting yellow-seed coat
CN1255541C (zh) 1997-06-05 2006-05-10 卡尔金有限责任公司 脂酰辅酶a：脂肪醇酰基转移酶
US6716474B2 (en) 1997-06-17 2004-04-06 Monsanto Technology Llc Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
US6441277B1 (en) 1997-06-17 2002-08-27 Monsanto Technology Llc Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
US6072103A (en) 1997-11-21 2000-06-06 Calgene Llc Pathogen and stress-responsive promoter for gene expression
US6023013A (en) 1997-12-18 2000-02-08 Monsanto Company Insect-resistant transgenic plants
US6060594A (en) 1997-12-18 2000-05-09 Ecogen, Inc. Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins
US6063597A (en) 1997-12-18 2000-05-16 Monsanto Company Polypeptide compositions toxic to coleopteran insects
US6653530B1 (en) 1998-02-13 2003-11-25 Calgene Llc Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds
US6107549A (en) 1998-03-10 2000-08-22 Monsanto Company Genetically engineered plant resistance to thiazopyr and other pyridine herbicides
US6284948B1 (en) 1998-05-18 2001-09-04 Pioneer Hi-Bred International, Inc. Genes and methods for control of nematodes in plants
CA2330180A1 (fr) 1998-06-05 1999-12-09 Calgene Llc Acyl coa : sequences d'acide nucleique en rapport avec la cholesterol acyltransferase
DK1086236T3 (da) 1998-06-12 2007-12-03 Calgene Llc Polyumættede fedtsyrer i planter
DE69941390D1 (de) 1998-07-02 2009-10-22 Calgene Llc Diacylglyzerin-acyltransferase proteine
DE69935857T2 (de) 1998-07-10 2008-01-10 Calgene Llc, Davis Expression eukarotischer peptide in pflanzenplastiden
US6476294B1 (en) 1998-07-24 2002-11-05 Calgene Llc Plant phosphatidic acid phosphatases
US6537750B1 (en) 1998-08-04 2003-03-25 Cargill Incorporated Plant fatty acid desaturase promoters
AR032578A1 (es) 1998-08-10 2003-11-19 Monsanto Technology Llc Metodos para controlar los niveles de giberelina
US6365802B2 (en) 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
DE69941009D1 (de) 1998-11-17 2009-07-30 Monsanto Technology Llc Phosphonat metabolisierende pflanzen
US6531648B1 (en) 1998-12-17 2003-03-11 Syngenta Participations Ag Grain processing method and transgenic plants useful therein
MXPA01010488A (es) 1999-04-15 2003-07-21 Calgene Llc Secuencias de acidos nucleicos para proteinas que intervienen en sintesis isoprenoide.
BR0010303A (pt) 1999-05-04 2002-02-13 Monsanto Technology Llc Composições de polipeptìdeos tóxicas para os coleópteros e plantas transgênicas resistentes aos insetos
MXPA01011671A (es) 1999-05-13 2002-06-04 Monsanto Technologies Llc Genes de resistencia adquirida en plantas.
CA2375540A1 (fr) 1999-06-08 2000-12-14 Calgene Llc Sequences d'acide nucleique codant des proteines impliquees dans la beta-oxydation des acides gras et procedes d'utilisation
US6770465B1 (en) 1999-06-09 2004-08-03 Calgene Llc Engineering B-ketoacyl ACP synthase for novel substrate specificity
WO2001004314A2 (fr) 1999-07-12 2001-01-18 Monsanto Technology, Llc. Molecules d'acide nucleique et autres molecules associees a la synthese et au metabolisme des sterols
US6501009B1 (en) 1999-08-19 2002-12-31 Monsanto Technology Llc Expression of Cry3B insecticidal protein in plants
CA2384967A1 (fr) 1999-09-15 2001-03-22 Monsanto Technology Llc Compositions d'endotoxines .delta. du bacillus thuringiensis actives contre les lepidopteres, et leurs procedes d'utilisation
US6573361B1 (en) 1999-12-06 2003-06-03 Monsanto Technology Llc Antifungal proteins and methods for their use
US6657046B1 (en) 2000-01-06 2003-12-02 Monsanto Technology Llc Insect inhibitory lipid acyl hydrolases
AU2631501A (en) 2000-01-06 2001-07-16 Monsanto Technology Llc Preparation of deallergenized proteins and permuteins
CA2401093A1 (fr) 2000-03-09 2001-09-13 Monsanto Technology Llc Procedes permettant de rendre des plantes tolerantes au glyphosate et compositions associees
US6518488B1 (en) 2000-07-21 2003-02-11 Monsanto Technology Llc Nucleic acid molecules and other molecules associated with the β-oxidation pathway
EP1303616A2 (fr) 2000-07-25 2003-04-23 Calgene LLC Sequences d'acide nucleique codantes pour la beta-cetoacyl-acp synthase et utilisation de celles-ci
US6949379B2 (en) 2000-10-20 2005-09-27 Canji, Inc. Aptamer-mediated regulation of gene expression
US7151204B2 (en) 2001-01-09 2006-12-19 Monsanto Technology Llc Maize chloroplast aldolase promoter compositions and methods for use thereof
DE10225066A1 (de) * 2002-06-06 2003-12-18 Basf Plant Science Gmbh Neue Expressionssysteme für Pflanzen
DE602004027403D1 (de) * 2003-11-10 2010-07-08 Icon Genetics Ag Von rna-virus abgeleitetes pflanzenexpressionssystem
US20160230185A1 (en) 2013-03-14 2016-08-11 Monsanto Technology Llc Compositions and methods for controlling diabrotica
US7703238B2 (en) 2004-08-26 2010-04-27 Monsanto Technology Llc Methods of seed breeding using high throughput nondestructive seed sampling
US8404927B2 (en) 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US20070199095A1 (en) 2005-10-13 2007-08-23 Edwards Allen Methods for producing hybrid seed
US8314290B2 (en) 2004-12-21 2012-11-20 Monsanto Technology Llc Temporal regulation of gene expression by MicroRNAs
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
AU2006203892B2 (en) 2005-01-07 2011-03-24 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
AR053279A1 (es) 2005-05-19 2007-04-25 Monsanto Technology Llc Regulacion post-transcripcional de la expresion genica
US7998669B2 (en) 2006-03-02 2011-08-16 Monsanto Technology Llc Automated contamination-free seed sampler and methods of sampling, testing and bulking seeds
EP2803728B1 (fr) 2006-05-16 2018-11-21 Monsanto Technology LLC Utilisation d'espèces bactériennes non agrobacterium pour la transformation de plantes
ES2655700T3 (es) 2006-08-31 2018-02-21 Monsanto Technology, Llc ARN pequeños en fase
AU2007352460C1 (en) 2006-10-12 2013-05-23 Monsanto Technology, Llc Plant microRNAs and methods of use thereof
CN101646769A (zh) 2007-02-20 2010-02-10 孟山都技术公司 无脊椎动物微rna
US20120165387A1 (en) 2007-08-28 2012-06-28 Smolke Christina D General composition framework for ligand-controlled RNA regulatory systems
ES2563485T3 (es) 2008-07-01 2016-03-15 Monsanto Technology Llc Construcciones de ADN recombinante y procedimientos para modular la expresión de un gen diana
AU2009285624B2 (en) 2008-08-29 2013-12-05 Monsanto Technology Llc Novel Hemipteran and coleopteran active toxin proteins from Bacillus thuringiensis
EP2417262B1 (fr) 2009-04-07 2015-05-20 Dow AgroSciences LLC Distribution à médiation par nanoparticules de nucléases à spécificité de séquence
JP2012523850A (ja) 2009-04-20 2012-10-11 モンサント テクノロジー エルエルシー 植物中の複数ウイルス抵抗性
AR074810A1 (es) 2009-10-23 2011-02-16 Monsanto Technology Llc Plantas y cromosomas de soja transgenica
CA2804168C (fr) 2010-07-07 2020-02-18 Dow Agrosciences Llc Delivrance d'une molecule d'adn lineaire utilisant des boites quantiques pegylees pour une transformation stable dans des plantes
CA2830531C (fr) 2011-03-23 2019-10-15 Dow Agrosciences Llc Conjugues peptidiques supports de points quantiques adaptes pour des applications d'imagerie et d'administration dans des plantes
PE20141518A1 (es) 2011-07-01 2014-11-17 Monsanto Technology Llc Metodos y composiciones para la regulacion selectiva de la expresion de proteinas
US20130145488A1 (en) 2011-12-06 2013-06-06 Iowa State University Research Foundation, Inc. Mesoporous silica nanoparticles suitable for co-delivery
US20130185823A1 (en) 2012-01-16 2013-07-18 Academia Sinica Mesoporous silica nanoparticle-mediated delivery of dna into arabidopsis root
US20140096284A1 (en) 2012-10-01 2014-04-03 Iowa State University Research Foundation, Inc. Method for the delivery of molecules lyophilized onto microparticles to plant tissues
US20150040268A1 (en) 2013-04-25 2015-02-05 Morflora Israel Ltd Methods and compositions for the delivery of nucleic acids to seeds
EP3003403A4 (fr) 2013-06-03 2017-02-22 University of Southern California Liposomes multilamellaires réticulés ciblés
JP6668236B2 (ja) 2013-07-19 2020-03-18 モンサント テクノロジー エルエルシー Ｌｅｐｔｉｎｏｔａｒｓａ防除用組成物及びその方法
WO2015021266A1 (fr) 2013-08-09 2015-02-12 Massachusetts Institute Of Technology Ingénierie nanobionique d'organites et organismes photosynthétiques
CA3221516A1 (fr) 2013-08-22 2015-02-26 E. I. Du Pont De Nemours And Company Modification du genome des plantes a l'aide de systemes d'arn de guida /endonuclease cas et leurs procedes d'utilisation
BR112016022711A2 (pt) 2014-04-01 2017-10-31 Monsanto Technology Llc composições e métodos para controle de pragas de inseto
AU2015296700B2 (en) 2014-07-29 2021-10-21 Monsanto Technology Llc Compositions and methods for controlling insect pests
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
MX388283B (es) 2014-10-16 2025-03-19 Monsanto Technology Llc Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros.
WO2016100804A1 (fr) 2014-12-19 2016-06-23 AgBiome, Inc. Procédés et compositions destinés à conférer une résistance au glufosinate
ES2996890T3 (en) 2015-11-18 2025-02-13 Monsanto Technology Llc Method of controlling insect pests
US10612037B2 (en) 2016-06-20 2020-04-07 Monsanto Technology Llc Insecticidal proteins toxic or inhibitory to hemipteran pests
MX394903B (es) 2016-09-09 2025-03-24 Syngenta Participations Ag Proteínas insecticidas.
AR109844A1 (es) 2016-10-27 2019-01-30 Syngenta Participations Ag Proteínas insecticidas
WO2018111946A1 (fr) 2016-12-12 2018-06-21 Integrated Dna Technologies, Inc. Détection d'édition de génome
UA125632C2 (uk) 2017-01-12 2022-05-04 Сінгента Партісіпейшнс Аг Інсектицидний білок
SG11201906795SA (en) 2017-01-28 2019-08-27 Inari Agriculture Inc Novel plant cells, plants, and seeds
WO2020021041A1 (fr) 2018-07-25 2020-01-30 Invaio Sciences International Gmbh Systèmes d'injection, outils d'injection et procédés associés
WO2021257987A2 (fr) * 2020-06-20 2021-12-23 Halo-Bio Rnai Therapeutics, Inc. Procédés et compositions de nanostructures d'arn pour la réplication et l'expression sous-génomique par l'arn polymérase dirigée par arn
AU2022315304A1 (en) 2021-07-23 2024-02-08 Flagship Pioneering Innovations Vii, Llc Compositions for fungal control and related methods

Also Published As

Publication number Publication date
CN121844053A (zh) 2026-04-10
AR132588A1 (es) 2025-07-16
WO2024229359A3 (fr) 2024-12-05
WO2024229359A2 (fr) 2024-11-07

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