EP4705474A2 - Arn satellite de tymovirales artificiels - Google Patents

Arn satellite de tymovirales artificiels

Info

Publication number
EP4705474A2
EP4705474A2 EP24729531.4A EP24729531A EP4705474A2 EP 4705474 A2 EP4705474 A2 EP 4705474A2 EP 24729531 A EP24729531 A EP 24729531A EP 4705474 A2 EP4705474 A2 EP 4705474A2
Authority
EP
European Patent Office
Prior art keywords
rna
virus
hrv
sequence
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24729531.4A
Other languages
German (de)
English (en)
Inventor
David George BLUMSACK
Fu Chyun CHU
Elizabeth Jane Antonelli DENNIS
Jean-Pierre Baptiste Séhi GLOUZON
Mehmet Ali HALAC
Yumeng HAO
Arjun Devang KHAKHAR
Kevin KLICKI
James Michael KREMER
Jayashree Kumar
Katherine Michelle LATOURRETTE
Barry Andrew Martin
Shankar Raj PANT
Derek Thomas ROTHENHEBER
Michka Gabrielle SHARPE
Aditya Sushil Kumar SINGH
Arjun Subedi
Phu Tri Tran
Paveena VICHYAVICHIEN
Reid Evan William WARSABA
Kaixi ZHAO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flagship Pioneering Innovations VII Inc
Original Assignee
Flagship Pioneering Innovations VII Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flagship Pioneering Innovations VII Inc filed Critical Flagship Pioneering Innovations VII Inc
Publication of EP4705474A2 publication Critical patent/EP4705474A2/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention divulgue des molécules d'ARN satellite de Tymovirales synthétiques et des particules satellites les contenant. L'invention concerne également des molécules d'ARN satellite de Tymovirales synthétiques qui contiennent des amplicons du virus à ARN hétérologue interne (HRV). Sont également divulguées des méthodes d'utilisation des molécules d'ARN satellite de Tymovirales et des particules satellites les contenant pour modifier les phénotypes des plantes, améliorer la résistance des plantes au stress et améliorer la résistance des plantes aux parasites et aux pathogènes.
EP24729531.4A 2023-05-03 2024-05-03 Arn satellite de tymovirales artificiels Pending EP4705474A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363499758P 2023-05-03 2023-05-03
PCT/US2024/027687 WO2024229359A2 (fr) 2023-05-03 2024-05-03 Arn satellite de tymovirales artificiels

Publications (1)

Publication Number Publication Date
EP4705474A2 true EP4705474A2 (fr) 2026-03-11

Family

ID=91302563

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24729531.4A Pending EP4705474A2 (fr) 2023-05-03 2024-05-03 Arn satellite de tymovirales artificiels

Country Status (4)

Country Link
EP (1) EP4705474A2 (fr)
CN (1) CN121844053A (fr)
AR (1) AR132588A1 (fr)
WO (1) WO2024229359A2 (fr)

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
JPH074232B2 (ja) 1984-12-10 1995-01-25 モンサントコンパニー バチルスチユウリンゲンシス結晶蛋白遺伝子の植物上での集落形成能を有する微生物への挿入及びその用途
US6774283B1 (en) 1985-07-29 2004-08-10 Calgene Llc Molecular farming
US6617496B1 (en) 1985-10-16 2003-09-09 Monsanto Company Effecting virus resistance in plants through the use of negative strand RNAs
US6608241B1 (en) 1985-10-29 2003-08-19 Monsanto Technology Llc Protection of plants against viral infection
US5322938A (en) 1987-01-13 1994-06-21 Monsanto Company DNA sequence for enhancing the efficiency of transcription
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
US5229114A (en) 1987-08-20 1993-07-20 The United States Of America As Represented By The Secretary Of Agriculture Approaches useful for the control of root nodulation of leguminous plants
US5597718A (en) 1988-10-04 1997-01-28 Agracetus Genetically engineering cotton plants for altered fiber
AU638438B2 (en) 1989-02-24 1993-07-01 Monsanto Technology Llc Synthetic plant genes and method for preparation
US5689041A (en) 1989-08-10 1997-11-18 Plant Gentic Systems N.V. Plants modified with barstar for fertility restoration
US5641876A (en) 1990-01-05 1997-06-24 Cornell Research Foundation, Inc. Rice actin gene and promoter
US6426447B1 (en) 1990-11-14 2002-07-30 Monsanto Technology Llc Plant seed oils
US5543576A (en) 1990-03-23 1996-08-06 Mogen International Production of enzymes in seeds and their use
US5969214A (en) 1990-06-11 1999-10-19 Calgene, Inc. Glycogen biosynthetic enzymes in plants
US5498830A (en) 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
EP0536293B1 (fr) 1990-06-18 2002-01-30 Monsanto Technology LLC Plantes a teneur en amidon augmentee
CA2083948C (fr) 1990-06-25 2001-05-15 Ganesh M. Kishore Plantes tolerantes au glyphosate
USRE38446E1 (en) 1990-07-20 2004-02-24 Calgene, Llc. Sucrose phosphate synthase (SPS), its process for preparation its cDNA, and utilization of cDNA to modify the expression of SPS in plant cells
US6483008B1 (en) 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
US5866775A (en) 1990-09-28 1999-02-02 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases
BR9107191A (pt) 1990-12-26 1994-06-14 Monsanto Co Controle de amadurecimento de frutos e senescência em plantas
US5304730A (en) 1991-09-03 1994-04-19 Monsanto Company Virus resistant plants and method therefore
US5763245A (en) 1991-09-23 1998-06-09 Monsanto Company Method of controlling insects
US6015940A (en) 1992-04-07 2000-01-18 Monsanto Company Virus resistant potato plants
US5850023A (en) 1992-11-30 1998-12-15 Monsanto Company Modified plant viral replicase genes
US6011199A (en) 1992-12-15 2000-01-04 Commonwealth Scientific Method for producing fruiting plants with improved fruit flavour
US6013864A (en) 1993-02-03 2000-01-11 Monsanto Company Plants resistant to infection by luteoviruses
US5322687A (en) 1993-07-29 1994-06-21 Ecogen Inc. Bacillus thuringiensis cryet4 and cryet5 toxin genes and proteins toxic to lepidopteran insects
AU7925094A (en) 1993-09-30 1995-04-18 Agracetus, Inc. Transgenic cotton plants producing heterologous peroxidase
JPH09506249A (ja) 1993-11-24 1997-06-24 モンサント・カンパニー 植物病原体の抑制方法
US5689052A (en) 1993-12-22 1997-11-18 Monsanto Company Synthetic DNA sequences having enhanced expression in monocotyledonous plants and method for preparation thereof
WO1998055632A1 (fr) 1997-06-05 1998-12-10 Calgene Llc Acyle gras-coa: alcool gras acyltransferase
US6828475B1 (en) 1994-06-23 2004-12-07 Calgene Llc Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-CoA metabolism
US6080560A (en) 1994-07-25 2000-06-27 Monsanto Company Method for producing antibodies in plant cells
US6140075A (en) 1994-07-25 2000-10-31 Monsanto Company Method for producing antibodies and protein toxins in plant cells
US5750876A (en) 1994-07-28 1998-05-12 Monsanto Company Isoamylase gene, compositions containing it, and methods of using isoamylases
US5716837A (en) 1995-02-10 1998-02-10 Monsanto Company Expression of sucrose phosphorylase in plants
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US6946588B2 (en) 1996-03-13 2005-09-20 Monsanto Technology Llc Nucleic acid encoding a modified threonine deaminase and methods of use
US6091002A (en) 1996-03-13 2000-07-18 Monsanto Company Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants
US5773696A (en) 1996-03-29 1998-06-30 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
US6166292A (en) 1996-04-26 2000-12-26 Ajinomoto Co., Inc. Raffinose synthetase gene, method of producing raffinose and transgenic plant
US5985605A (en) 1996-06-14 1999-11-16 Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada DNA sequences encoding phytases of ruminal microorganisms
US5998700A (en) 1996-07-02 1999-12-07 The Board Of Trustees Of Southern Illinois University Plants containing a bacterial Gdha gene and methods of use thereof
US5750848A (en) 1996-08-13 1998-05-12 Monsanto Company DNA sequence useful for the production of polyhydroxyalkanoates
US6063756A (en) 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
US6093695A (en) 1996-09-26 2000-07-25 Monsanto Company Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and ctenocephalides SPP
JP2002510961A (ja) 1996-10-29 2002-04-09 カルジーン エル エル シー 植物セルロースシンターゼおよびプロモーター配列
US6713063B1 (en) 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
US6017534A (en) 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
AP9901541A0 (en) 1996-11-20 1999-06-30 Ecogen Inc Broad-spectrum delta-endotoxins.
US5942664A (en) 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
WO1998027104A1 (fr) 1996-12-19 1998-06-25 Yale University Polynucleotides allosteres bioreactifs
US6171640B1 (en) 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US6372211B1 (en) 1997-04-21 2002-04-16 Monsanto Technolgy Llc Methods and compositions for controlling insects
US6380466B1 (en) 1997-05-08 2002-04-30 Calgene Llc Production of improved rapeseed exhibiting yellow-seed coat
US6716474B2 (en) 1997-06-17 2004-04-06 Monsanto Technology Llc Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
US6441277B1 (en) 1997-06-17 2002-08-27 Monsanto Technology Llc Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
US6072103A (en) 1997-11-21 2000-06-06 Calgene Llc Pathogen and stress-responsive promoter for gene expression
US6060594A (en) 1997-12-18 2000-05-09 Ecogen, Inc. Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins
US6023013A (en) 1997-12-18 2000-02-08 Monsanto Company Insect-resistant transgenic plants
US6063597A (en) 1997-12-18 2000-05-16 Monsanto Company Polypeptide compositions toxic to coleopteran insects
US6653530B1 (en) 1998-02-13 2003-11-25 Calgene Llc Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds
US6107549A (en) 1998-03-10 2000-08-22 Monsanto Company Genetically engineered plant resistance to thiazopyr and other pyridine herbicides
US6284948B1 (en) 1998-05-18 2001-09-04 Pioneer Hi-Bred International, Inc. Genes and methods for control of nematodes in plants
US6444876B1 (en) 1998-06-05 2002-09-03 Calgene Llc Acyl CoA: cholesterol acyltransferase related nucleic acid sequences
CA2330024C (fr) 1998-06-12 2012-01-24 Calgene Llc Acides gras polyinsatures vegetaux
JP4514952B2 (ja) 1998-07-02 2010-07-28 カルジーン エルエルシー ジアシルグリセロールアシルトランスフェラーゼタンパク質
JP2002520019A (ja) 1998-07-10 2002-07-09 カルジーン エルエルシー 植物色素体における真核性ペプチドの発現
US6476294B1 (en) 1998-07-24 2002-11-05 Calgene Llc Plant phosphatidic acid phosphatases
CN1219064C (zh) 1998-08-04 2005-09-14 嘉吉有限公司 植物脂肪酸去饱和酶启动子
AU5346099A (en) 1998-08-10 2000-03-06 Monsanto Company Methods for controlling gibberellin levels
US6365802B2 (en) 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
EP1135511B1 (fr) 1998-11-17 2009-06-17 Monsanto Technology LLC Plantes metabolisant les phosphonates
US6531648B1 (en) 1998-12-17 2003-03-11 Syngenta Participations Ag Grain processing method and transgenic plants useful therein
JP2003527077A (ja) 1999-04-15 2003-09-16 カルジーン エルエルシー トコフェロール合成に関与するタンパク質の核酸配列
US6555655B1 (en) 1999-05-04 2003-04-29 Monsanto Technology, Llc Coleopteran-toxic polypeptide compositions and insect-resistant transgenic plants
CN1350587A (zh) 1999-05-13 2002-05-22 孟山都技术有限公司 植物的获得性抗性基因
EP1190078A2 (fr) 1999-06-08 2002-03-27 Calgene LLC Sequences d'acide nucleique codant des proteines impliquees dans la beta-oxydation des acides gras et procedes d'utilisation
US6770465B1 (en) 1999-06-09 2004-08-03 Calgene Llc Engineering B-ketoacyl ACP synthase for novel substrate specificity
WO2001004314A2 (fr) 1999-07-12 2001-01-18 Monsanto Technology, Llc. Molecules d'acide nucleique et autres molecules associees a la synthese et au metabolisme des sterols
US6501009B1 (en) 1999-08-19 2002-12-31 Monsanto Technology Llc Expression of Cry3B insecticidal protein in plants
US6593293B1 (en) 1999-09-15 2003-07-15 Monsanto Technology, Llc Lepidopteran-active Bacillus thuringiensis δ-endotoxin compositions and methods of use
US6573361B1 (en) 1999-12-06 2003-06-03 Monsanto Technology Llc Antifungal proteins and methods for their use
US6657046B1 (en) 2000-01-06 2003-12-02 Monsanto Technology Llc Insect inhibitory lipid acyl hydrolases
MXPA02006752A (es) 2000-01-06 2004-09-10 Monsanto Technology Llc Preparacion de proteinas y permutenias desalergenizadas.
EP1261695B1 (fr) 2000-03-09 2005-06-22 Monsanto Technology LLC Procedes permettant de rendre des plantes tolerantes au glyphosate et compositions associees
US6518488B1 (en) 2000-07-21 2003-02-11 Monsanto Technology Llc Nucleic acid molecules and other molecules associated with the β-oxidation pathway
AU2001279007A1 (en) 2000-07-25 2002-02-05 Calgene Llc Nucleic acid sequences encoding beta-ketoacyl-acp synthase and uses thereof
CA2440367A1 (fr) 2000-10-20 2002-08-15 Canji, Inc. Regulation de l'expression genique au moyen d'aptameres
US7151204B2 (en) 2001-01-09 2006-12-19 Monsanto Technology Llc Maize chloroplast aldolase promoter compositions and methods for use thereof
DE10225066A1 (de) * 2002-06-06 2003-12-18 Basf Plant Science Gmbh Neue Expressionssysteme für Pflanzen
EP1682667B1 (fr) * 2003-11-10 2010-05-26 Icon Genetics GmbH Systeme d'expression dans les vegetaux derive d'un virus à arn
US20160230185A1 (en) 2013-03-14 2016-08-11 Monsanto Technology Llc Compositions and methods for controlling diabrotica
US7703238B2 (en) 2004-08-26 2010-04-27 Monsanto Technology Llc Methods of seed breeding using high throughput nondestructive seed sampling
US8404927B2 (en) 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US8314290B2 (en) 2004-12-21 2012-11-20 Monsanto Technology Llc Temporal regulation of gene expression by MicroRNAs
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
US8030473B2 (en) 2005-01-07 2011-10-04 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
AR053279A1 (es) 2005-05-19 2007-04-25 Monsanto Technology Llc Regulacion post-transcripcional de la expresion genica
EA023885B1 (ru) 2005-10-13 2016-07-29 МОНСАНТО ТЕКНОЛОДЖИ, ЭлЭлСи Конструкция рекомбинантной днк для индуцирования стерильности в трансгенном растении, стерильные трансгенные растения и способы получения гибридных семян
US7998669B2 (en) 2006-03-02 2011-08-16 Monsanto Technology Llc Automated contamination-free seed sampler and methods of sampling, testing and bulking seeds
CA2843961A1 (fr) 2006-05-16 2007-11-29 Monsanto Technology Llc Utilisation d'especes bateriennes non agrobacteriennes pour la transformation de plantes
WO2008027592A2 (fr) 2006-08-31 2008-03-06 Monsanto Technology, Llc Petits arn en phase
EP2985353A1 (fr) 2006-10-12 2016-02-17 Monsanto Technology LLC Micro-arn de plantes et leurs procédés d'utilisation
EP2115141A4 (fr) 2007-02-20 2010-08-04 Monsanto Technology Llc Micro-arn d'invertebres
US20120165387A1 (en) 2007-08-28 2012-06-28 Smolke Christina D General composition framework for ligand-controlled RNA regulatory systems
AU2009267007B2 (en) 2008-07-01 2016-02-25 Monsanto Technology, Llc Recombinant DNA constructs and methods for modulating expression of a target gene
AR073237A1 (es) 2008-08-29 2010-10-20 Monsanto Technology Llc Proteinas de bacillus thuringiensis que son toxinas activas contra hemipteros y coleopteros
TWI576432B (zh) 2009-04-07 2017-04-01 陶氏農業科學公司 序列特異性核酸酶之奈米粒子媒介式遞送技術
CA2759291C (fr) 2009-04-20 2020-09-15 Monsanto Technology Llc Resistance multi virus dans les plants de tomate transgeniques
WO2011049587A1 (fr) 2009-10-23 2011-04-28 Monsanto Technology Llc Plants et chromosomes de soja transgénique
UA113046C2 (xx) 2010-07-07 2016-12-12 Спосіб введення лінійної молекули нуклеїнової кислоти в клітину рослини, яка має клітинну стінку, із застосуванням пегильованих напівпровідникових наночастинок
EP2697379B1 (fr) 2011-03-23 2018-08-29 Dow AgroSciences LLC Conjugués peptidiques supports de points quantiques adaptés pour des applications d'imagerie et d'administration dans des plantes
CN103635483B (zh) 2011-07-01 2016-11-09 孟山都技术公司 用于选择性调控蛋白质表达的方法和组合物
US20130145488A1 (en) 2011-12-06 2013-06-06 Iowa State University Research Foundation, Inc. Mesoporous silica nanoparticles suitable for co-delivery
US20130185823A1 (en) 2012-01-16 2013-07-18 Academia Sinica Mesoporous silica nanoparticle-mediated delivery of dna into arabidopsis root
US20140096284A1 (en) 2012-10-01 2014-04-03 Iowa State University Research Foundation, Inc. Method for the delivery of molecules lyophilized onto microparticles to plant tissues
US20150040268A1 (en) 2013-04-25 2015-02-05 Morflora Israel Ltd Methods and compositions for the delivery of nucleic acids to seeds
AU2014275045A1 (en) 2013-06-03 2015-12-17 University Of Southern California Targeted crosslinked multilamellar liposomes
RU2703498C2 (ru) 2013-07-19 2019-10-17 Монсанто Текнолоджи Ллс Композиции и способы борьбы с leptinotarsa
WO2015021266A1 (fr) 2013-08-09 2015-02-12 Massachusetts Institute Of Technology Ingénierie nanobionique d'organites et organismes photosynthétiques
CN120574876A (zh) 2013-08-22 2025-09-02 纳幕尔杜邦公司 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法
BR112016022711A2 (pt) 2014-04-01 2017-10-31 Monsanto Technology Llc composições e métodos para controle de pragas de inseto
RU2021123470A (ru) 2014-07-29 2021-09-06 Монсанто Текнолоджи Ллс Композиции и способы борьбы с насекомыми-вредителями
JP6626102B2 (ja) 2014-10-16 2019-12-25 モンサント テクノロジー エルエルシー 鱗翅目害虫に有毒または阻害性の新規キメラ殺虫性タンパク質
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
US10947556B2 (en) 2014-12-19 2021-03-16 AgBiome, Inc. Sequences to facilitate incorporation of DNA into the genome of an organism
PL3377486T3 (pl) 2015-11-18 2025-02-24 Monsanto Technology Llc Sposób zwalczania szkodników owadzich
US10612037B2 (en) 2016-06-20 2020-04-07 Monsanto Technology Llc Insecticidal proteins toxic or inhibitory to hemipteran pests
WO2018048525A1 (fr) 2016-09-09 2018-03-15 Syngenta Participations Ag Protéines insecticides
AR109844A1 (es) 2016-10-27 2019-01-30 Syngenta Participations Ag Proteínas insecticidas
US20190032131A1 (en) 2016-12-12 2019-01-31 Integrated Dna Technologies, Inc. Genome editing detection
RU2761666C2 (ru) 2017-01-12 2021-12-13 Зингента Партисипейшнс Аг Инсектицидные белки
WO2018140899A1 (fr) 2017-01-28 2018-08-02 Inari Agriculture, Inc. Nouvelles cellules végétales, plantes et semences
JP7454575B2 (ja) 2018-07-25 2024-03-22 インヴァイオ サイエンシズ インターナショナル ゲーエムベーハー 注入システム、注入器具及びそのための方法
US20230227830A1 (en) * 2020-06-20 2023-07-20 Halo-Bio Rnai Therapeutics, Inc. Methods and compositions of rna nanostructures for replication and sub-genomic expression by rna-directed rna polymerase
TW202332686A (zh) 2021-07-23 2023-08-16 美商旗艦先鋒創新有限責（Ｖｉｉ））公司 用於真菌控制的組成物和相關方法

Also Published As

Publication number Publication date
AR132588A1 (es) 2025-07-16
WO2024229359A2 (fr) 2024-11-07
CN121844053A (zh) 2026-04-10
WO2024229359A3 (fr) 2024-12-05

Similar Documents

Publication Publication Date Title
US12529067B2 (en) Methods for modifying plants with a recombinant RNA molecule
US20250230452A1 (en) Polynucleotides for modifying organisms
CN102046796B (zh) 用于植物害虫控制的方法和组合物
US11578338B2 (en) Hemipteran active insecticidal protein
CN118556127A (zh) 用于修饰生物体的多核苷酸
EP4705474A2 (fr) Arn satellite de tymovirales artificiels
WO2024229362A1 (fr) Arn satellites martellivirales artificiels
WO2024229356A2 (fr) Arn satellites de solemoviridae artificiels
WO2024229398A1 (fr) Arn satellite d'amalgavirus artificiel
WO2024229385A1 (fr) Arn satellite a base de ghabrivirales artificielles
WO2024229395A1 (fr) Systèmes d'amplification d'arn satellite de partitivirus pour plantes
EP4705472A1 (fr) Arn satellite de secoviridae artificiels
EP4705470A1 (fr) Arn satellite de tombusviridae artificiel
EP4705477A1 (fr) Systèmes d'amplification d'arn satellite endornaviral pour plantes
CN118922549A (zh) 用于修饰生物体的多核苷酸

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20251030

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR