EP4706054A2 - Procédé et système de codage de règles de dosage d'insuline dans un pancréas artificiel à réseau neuronal (nap) destiné au traitement informatisé du diabète - Google Patents

Procédé et système de codage de règles de dosage d'insuline dans un pancréas artificiel à réseau neuronal (nap) destiné au traitement informatisé du diabète

Info

Publication number
EP4706054A2
EP4706054A2 EP24800437.6A EP24800437A EP4706054A2 EP 4706054 A2 EP4706054 A2 EP 4706054A2 EP 24800437 A EP24800437 A EP 24800437A EP 4706054 A2 EP4706054 A2 EP 4706054A2
Authority
EP
European Patent Office
Prior art keywords
insulin
processor
instructions
saturated
model
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24800437.6A
Other languages
German (de)
English (en)
Inventor
Alberto Castillo FRASQUET
Marc D. Breton
Elliott Carroll PRYOR
Boris P. Kovatchev
Patricio COLMEGNA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UVA Licensing and Ventures Group
Original Assignee
University of Virginia Patent Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Virginia Patent Foundation filed Critical University of Virginia Patent Foundation
Publication of EP4706054A2 publication Critical patent/EP4706054A2/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/08—Learning methods
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Theoretical Computer Science (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Databases & Information Systems (AREA)
  • Software Systems (AREA)
  • General Physics & Mathematics (AREA)
  • Artificial Intelligence (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Mathematical Physics (AREA)
  • Evolutionary Computation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Computational Linguistics (AREA)
  • Molecular Biology (AREA)
  • Business, Economics & Management (AREA)
  • General Business, Economics & Management (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • External Artificial Organs (AREA)

Abstract

Des modes de réalisation concernent des systèmes et des procédés de développement et de mise en œuvre d'un modèle. Le développement du modèle peut impliquer la réception d'une règle de dosage d'insuline (IDR) comprenant plusieurs états métaboliques (X) et des recommandations de dosage d'insuline correspondantes (U), la génération d'un ensemble de données saturées avec la pluralité de X et les U correspondantes de telle sorte que l'ensemble de données saturées présente une densité de données optimale, la génération d'une table de consultation saturée (STL) avec l'ensemble de données saturées, et le codage de la STL dans un réseau neuronal. La mise en œuvre du modèle peut impliquer la réception d'une mesure indicative d'un état métabolique (Xm), la mise en œuvre d'un modèle d'un SLT codé dans un réseau neuronal, le SLT comprenant un ensemble de données saturées de densité de données optimale, la mise en œuvre du modèle appliquant Xm au SLT pour identifier une U correspondante, et la surveillance, l'analyse ou l'influence d'une concentration de niveaux de glucose dans un fluide à l'aide de l'U identifiée.
EP24800437.6A 2023-05-01 2024-04-30 Procédé et système de codage de règles de dosage d'insuline dans un pancréas artificiel à réseau neuronal (nap) destiné au traitement informatisé du diabète Pending EP4706054A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363463232P 2023-05-01 2023-05-01
PCT/US2024/027020 WO2024229007A2 (fr) 2023-05-01 2024-04-30 Procédé et système de codage de règles de dosage d'insuline dans un pancréas artificiel à réseau neuronal (nap) destiné au traitement informatisé du diabète

Publications (1)

Publication Number Publication Date
EP4706054A2 true EP4706054A2 (fr) 2026-03-11

Family

ID=93333279

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24800437.6A Pending EP4706054A2 (fr) 2023-05-01 2024-04-30 Procédé et système de codage de règles de dosage d'insuline dans un pancréas artificiel à réseau neuronal (nap) destiné au traitement informatisé du diabète

Country Status (2)

Country Link
EP (1) EP4706054A2 (fr)
WO (1) WO2024229007A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8548544B2 (en) * 2006-06-19 2013-10-01 Dose Safety System, method and article for controlling the dispensing of insulin
US20210259591A1 (en) * 2020-02-20 2021-08-26 Dexcom, Inc. Machine learning in an artificial pancreas
CN112927802B (zh) * 2021-01-28 2022-07-19 北京理工大学 一种专家经验辅助的餐前胰岛素剂量学习优化决策系统

Also Published As

Publication number Publication date
WO2024229007A2 (fr) 2024-11-07
WO2024229007A3 (fr) 2025-01-23

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