EP4709370A2 - Stat-abbauer und verwendungen davon - Google Patents

Stat-abbauer und verwendungen davon

Info

Publication number
EP4709370A2
EP4709370A2 EP24804192.3A EP24804192A EP4709370A2 EP 4709370 A2 EP4709370 A2 EP 4709370A2 EP 24804192 A EP24804192 A EP 24804192A EP 4709370 A2 EP4709370 A2 EP 4709370A2
Authority
EP
European Patent Office
Prior art keywords
alkyl
halo
phenyl
compound
membered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24804192.3A
Other languages
English (en)
French (fr)
Inventor
Howard Bregman
Neil Bifulco
Giovanni Cianchetta
Brian Hodous
Samuel K. REZNIK
Ernest Allen SICKMIER
Yong Tang
Andrew Tasker
Xia TIAN
Rishi G. Vaswani
John Yeoman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recludix Pharma Inc
Original Assignee
Recludix Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recludix Pharma Inc filed Critical Recludix Pharma Inc
Publication of EP4709370A2 publication Critical patent/EP4709370A2/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP24804192.3A 2023-05-09 2024-05-08 Stat-abbauer und verwendungen davon Pending EP4709370A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363465055P 2023-05-09 2023-05-09
PCT/US2024/028326 WO2024233639A2 (en) 2023-05-09 2024-05-08 Stat degraders and uses thereof

Publications (1)

Publication Number Publication Date
EP4709370A2 true EP4709370A2 (de) 2026-03-18

Family

ID=93431152

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24804192.3A Pending EP4709370A2 (de) 2023-05-09 2024-05-08 Stat-abbauer und verwendungen davon

Country Status (2)

Country Link
EP (1) EP4709370A2 (de)
WO (1) WO2024233639A2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020198435A1 (en) * 2019-03-26 2020-10-01 The Regents Of The University Of Michigan Small molecule degraders of stat3
CA3170503A1 (en) * 2020-03-17 2021-09-23 Nan JI Stat degraders and uses thereof
IL301830A (en) * 2020-10-07 2023-06-01 Kymera Therapeutics Inc Stat degraders and uses thereof
KR20240167786A (ko) * 2022-01-10 2024-11-28 레클루딕스 파마, 인크. Stat 조정제 및 그의 용도

Also Published As

Publication number Publication date
WO2024233639A2 (en) 2024-11-14
WO2024233639A3 (en) 2025-03-27

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Legal Events

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