EP4713342A2 - Systeme und verfahren zur regulierung von zielgenen - Google Patents

Systeme und verfahren zur regulierung von zielgenen

Info

Publication number
EP4713342A2
EP4713342A2 EP24808013.7A EP24808013A EP4713342A2 EP 4713342 A2 EP4713342 A2 EP 4713342A2 EP 24808013 A EP24808013 A EP 24808013A EP 4713342 A2 EP4713342 A2 EP 4713342A2
Authority
EP
European Patent Office
Prior art keywords
peptide
sequence
sequences
engineered gene
effector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24808013.7A
Other languages
English (en)
French (fr)
Inventor
Daniel O. HART
Lei S. QI
Thomas Blair GAINOUS
Giovanni CAROSSO
Tengyu KO
Robin W. YEO
Muhammad Zaki JAWAID
Brandon W. LIAUW
Xiao Yang
Yanxia Liu
Timothy Daley
II Christopher Darryl Still
Melanie R. SILVIS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epicrispr Biotechnologies Inc
Original Assignee
Epicrispr Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epicrispr Biotechnologies Inc filed Critical Epicrispr Biotechnologies Inc
Publication of EP4713342A2 publication Critical patent/EP4713342A2/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C12N9/222—Clustered regularly interspaced short palindromic repeats [CRISPR]-associated [CAS] enzymes
    • C12N9/226—Class 2 CAS enzyme complex, e.g. single CAS protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP24808013.7A 2023-05-17 2024-05-15 Systeme und verfahren zur regulierung von zielgenen Pending EP4713342A2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US202363502891P 2023-05-17 2023-05-17
US202363504661P 2023-05-26 2023-05-26
US202363504663P 2023-05-26 2023-05-26
US202363504660P 2023-05-26 2023-05-26
US202363520251P 2023-08-17 2023-08-17
PCT/US2024/029475 WO2024238661A2 (en) 2023-05-17 2024-05-15 Systems and methods for regulating target genes

Publications (1)

Publication Number Publication Date
EP4713342A2 true EP4713342A2 (de) 2026-03-25

Family

ID=93520135

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24808013.7A Pending EP4713342A2 (de) 2023-05-17 2024-05-15 Systeme und verfahren zur regulierung von zielgenen

Country Status (3)

Country Link
EP (1) EP4713342A2 (de)
CN (1) CN121532411A (de)
WO (1) WO2024238661A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119986006A (zh) * 2025-02-25 2025-05-13 广州医科大学附属第三医院（广州重症孕产妇救治中心、广州柔济医院） 用于检测gysy-1多肽的试剂在制备结肠癌预后和免疫治疗敏感性评估的产品中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024526895A (ja) * 2021-07-20 2024-07-19 エピクリスパー バイオテクノロジーズ， インコーポレイテッド 標的遺伝子を調節するための系および方法

Also Published As

Publication number Publication date
WO2024238661A2 (en) 2024-11-21
WO2024238661A3 (en) 2025-03-20
CN121532411A (zh) 2026-02-13

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