EP4720064A1 - Azolés fusionnés en tant qu'inhibiteurs de tyk2 et leurs utilisations - Google Patents

Azolés fusionnés en tant qu'inhibiteurs de tyk2 et leurs utilisations

Info

Publication number
EP4720064A1
EP4720064A1 EP24737171.9A EP24737171A EP4720064A1 EP 4720064 A1 EP4720064 A1 EP 4720064A1 EP 24737171 A EP24737171 A EP 24737171A EP 4720064 A1 EP4720064 A1 EP 4720064A1
Authority
EP
European Patent Office
Prior art keywords
substituted
unsubstituted
alkyl
fluoroalkyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24737171.9A
Other languages
German (de)
English (en)
Inventor
Anjali Pandey
Seetharaman MANOJVEER
Mahesh THAKKAR
Athisayamani Jeyaraj DURAISWAMY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sudo Biosciences Ltd
Original Assignee
Sudo Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sudo Biosciences Ltd filed Critical Sudo Biosciences Ltd
Publication of EP4720064A1 publication Critical patent/EP4720064A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés qui sont des inhibiteurs de TYK2, des procédés de fabrication de tels composés, des compositions pharmaceutiques et des médicaments comprenant de tels composés, et des méthodes d'utilisation de tels composés dans le traitement d'affections, de maladies ou de troubles pour lesquels la modulation de l'activité de TYK2 serait bénéfique. Formule (I)
EP24737171.9A 2023-05-26 2024-05-23 Azolés fusionnés en tant qu'inhibiteurs de tyk2 et leurs utilisations Pending EP4720064A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363504718P 2023-05-26 2023-05-26
US202363602921P 2023-11-27 2023-11-27
PCT/IB2024/000257 WO2024246602A1 (fr) 2023-05-26 2024-05-23 Azolés fusionnés en tant qu'inhibiteurs de tyk2 et leurs utilisations

Publications (1)

Publication Number Publication Date
EP4720064A1 true EP4720064A1 (fr) 2026-04-08

Family

ID=91738356

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24737171.9A Pending EP4720064A1 (fr) 2023-05-26 2024-05-23 Azolés fusionnés en tant qu'inhibiteurs de tyk2 et leurs utilisations

Country Status (2)

Country Link
EP (1) EP4720064A1 (fr)
WO (1) WO2024246602A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4294806A1 (fr) 2021-02-19 2023-12-27 Sudo Biosciences Limited Inhibiteurs de tyk2 et leurs utilisations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4294806A1 (fr) * 2021-02-19 2023-12-27 Sudo Biosciences Limited Inhibiteurs de tyk2 et leurs utilisations
AU2022222470A1 (en) * 2021-02-19 2023-09-21 Sudo Biosciences Limited Tyk2 inhibitors and uses thereof

Also Published As

Publication number Publication date
WO2024246602A1 (fr) 2024-12-05

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