EP4720092A1 - Synthetische tnfr1-bindende proteine, herstellung und verwendungen davon - Google Patents

Synthetische tnfr1-bindende proteine, herstellung und verwendungen davon

Info

Publication number
EP4720092A1
EP4720092A1 EP24816417.0A EP24816417A EP4720092A1 EP 4720092 A1 EP4720092 A1 EP 4720092A1 EP 24816417 A EP24816417 A EP 24816417A EP 4720092 A1 EP4720092 A1 EP 4720092A1
Authority
EP
European Patent Office
Prior art keywords
amino acid
acid sequence
seq
tnfr1
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24816417.0A
Other languages
English (en)
French (fr)
Inventor
III James Wayne BOWMAN
Christopher David BAHL
III Frank David TEETS
Edson Norberto Carcamo NORIEGA
Ben Alexander MEINEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aip 001 Inc
Original Assignee
Aip 001 Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aip 001 Inc filed Critical Aip 001 Inc
Publication of EP4720092A1 publication Critical patent/EP4720092A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
EP24816417.0A 2023-05-31 2024-05-30 Synthetische tnfr1-bindende proteine, herstellung und verwendungen davon Pending EP4720092A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363505423P 2023-05-31 2023-05-31
PCT/US2024/031670 WO2024249633A1 (en) 2023-05-31 2024-05-30 Synthetic tnfr1 binding proteins, manufacture, and uses thereof

Publications (1)

Publication Number Publication Date
EP4720092A1 true EP4720092A1 (de) 2026-04-08

Family

ID=93658503

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24816417.0A Pending EP4720092A1 (de) 2023-05-31 2024-05-30 Synthetische tnfr1-bindende proteine, herstellung und verwendungen davon

Country Status (6)

Country Link
EP (1) EP4720092A1 (de)
JP (1) JP2026520510A (de)
KR (1) KR20260020413A (de)
CN (1) CN121586721A (de)
AU (1) AU2024279102A1 (de)
WO (1) WO2024249633A1 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005015206A2 (en) * 2003-08-08 2005-02-17 Genova Ltd. Secreted polypeptide species associated with cardiovascular disorders

Also Published As

Publication number Publication date
WO2024249633A1 (en) 2024-12-05
KR20260020413A (ko) 2026-02-11
CN121586721A (zh) 2026-02-27
AU2024279102A9 (en) 2026-01-08
JP2026520510A (ja) 2026-06-23
AU2024279102A1 (en) 2025-12-11

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