EP4720093A2 - Procédés de fabrication de conjugués peptidiques et produit fabriqué à partir de ceux-ci - Google Patents

Procédés de fabrication de conjugués peptidiques et produit fabriqué à partir de ceux-ci

Info

Publication number
EP4720093A2
EP4720093A2 EP24816508.6A EP24816508A EP4720093A2 EP 4720093 A2 EP4720093 A2 EP 4720093A2 EP 24816508 A EP24816508 A EP 24816508A EP 4720093 A2 EP4720093 A2 EP 4720093A2
Authority
EP
European Patent Office
Prior art keywords
peptide
compound
seq
hrc
linker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24816508.6A
Other languages
German (de)
English (en)
Inventor
Bradley Pentelute
Barbara L. HIBNER
Linhai JIANG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Decoy Therapeutics Inc
Original Assignee
Decoy Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decoy Therapeutics Inc filed Critical Decoy Therapeutics Inc
Publication of EP4720093A2 publication Critical patent/EP4720093A2/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un procédé de synthèse de conjugués peptidiques par chimie en flux automatisé, le procédé comprenant la synthèse d'une structure covalente se liant à différents modules, la structure covalente comprenant au moins un acide diaminoaliphatique, de préférence la lysine ; ainsi que le produit obtenu à partir de celui-ci, par exemple, des conjugués peptidiques antiviraux.
EP24816508.6A 2023-06-01 2024-05-31 Procédés de fabrication de conjugués peptidiques et produit fabriqué à partir de ceux-ci Pending EP4720093A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363470257P 2023-06-01 2023-06-01
PCT/US2024/031869 WO2024249765A2 (fr) 2023-06-01 2024-05-31 Procédés de fabrication de conjugués peptidiques et produit fabriqué à partir de ceux-ci

Publications (1)

Publication Number Publication Date
EP4720093A2 true EP4720093A2 (fr) 2026-04-08

Family

ID=93658727

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24816508.6A Pending EP4720093A2 (fr) 2023-06-01 2024-05-31 Procédés de fabrication de conjugués peptidiques et produit fabriqué à partir de ceux-ci

Country Status (4)

Country Link
EP (1) EP4720093A2 (fr)
CN (1) CN121712791A (fr)
AU (1) AU2024278914A1 (fr)
WO (1) WO2024249765A2 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022343A1 (fr) * 1992-05-01 1993-11-11 The Rockfeller University Systeme antigenique a plusieurs peptides possedant des proprietes d'adjuvant, vaccins prepares a partir dudit systeme
WO2022159372A1 (fr) * 2021-01-22 2022-07-28 Decoy Therapeutics, Inc. Procédés et compositions pour traiter des infections

Also Published As

Publication number Publication date
WO2024249765A3 (fr) 2025-03-13
WO2024249765A2 (fr) 2024-12-05
AU2024278914A1 (en) 2026-01-15
CN121712791A (zh) 2026-03-20

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