EP4723063A2 - Computervorrichtung zur erkennung einer optimalen kandidatenverbindung und verfahren dafür - Google Patents

Computervorrichtung zur erkennung einer optimalen kandidatenverbindung und verfahren dafür

Info

Publication number
EP4723063A2
EP4723063A2 EP26159568.0A EP26159568A EP4723063A2 EP 4723063 A2 EP4723063 A2 EP 4723063A2 EP 26159568 A EP26159568 A EP 26159568A EP 4723063 A2 EP4723063 A2 EP 4723063A2
Authority
EP
European Patent Office
Prior art keywords
class
cell
image data
profiles
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP26159568.0A
Other languages
English (en)
French (fr)
Inventor
Emmanuel Israel Fuentes
Gopal Biligeri Avinash
Robert John Graves
Abhijit Vijay Thatte
Afek KODESH
Jeffery Caron
Sharmistha Das
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Devices LLC
Original Assignee
Molecular Devices LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Devices LLC filed Critical Molecular Devices LLC
Publication of EP4723063A2 publication Critical patent/EP4723063A2/de
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50—Molecular design, e.g. of drugs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/20—Identification of molecular entities, parts thereof or of chemical compositions
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/23—Clustering techniques
    • G06F18/232—Non-hierarchical techniques
    • G06F18/2321—Non-hierarchical techniques using statistics or function optimisation, e.g. modelling of probability density functions
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/762—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks
    • G06V10/763—Non-hierarchical techniques, e.g. based on statistics of modelling distributions
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/70—Machine learning, data mining or chemometrics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/80—Data visualisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
    • G06F2218/12—Classification; Matching
    • G06F2218/16—Classification; Matching by matching signal segments
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2200/00—Indexing scheme for image data processing or generation, in general
    • G06T2200/24—Indexing scheme for image data processing or generation, in general involving graphical user interfaces [GUIs]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Data Mining & Analysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Medical Informatics (AREA)
  • Computing Systems (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Software Systems (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • Molecular Biology (AREA)
  • Probability & Statistics with Applications (AREA)
  • Multimedia (AREA)
  • Databases & Information Systems (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Image Analysis (AREA)
EP26159568.0A 2016-09-30 2017-10-02 Computervorrichtung zur erkennung einer optimalen kandidatenverbindung und verfahren dafür Pending EP4723063A2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662402272P 2016-09-30 2016-09-30
PCT/EP2017/075003 WO2018060523A2 (en) 2016-09-30 2017-10-02 Computer device for detecting an optimal candidate compound and methods thereof
EP17787343.7A EP3520004B1 (de) 2016-09-30 2017-10-02 Computervorrichtung zur detektion einer optimalen kandidatenverbindung und verfahren dafür

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP17787343.7A Division EP3520004B1 (de) 2016-09-30 2017-10-02 Computervorrichtung zur detektion einer optimalen kandidatenverbindung und verfahren dafür
EP17787343.7A Division-Into EP3520004B1 (de) 2016-09-30 2017-10-02 Computervorrichtung zur detektion einer optimalen kandidatenverbindung und verfahren dafür

Publications (1)

Publication Number Publication Date
EP4723063A2 true EP4723063A2 (de) 2026-04-08

Family

ID=60153264

Family Applications (2)

Application Number Title Priority Date Filing Date
EP17787343.7A Active EP3520004B1 (de) 2016-09-30 2017-10-02 Computervorrichtung zur detektion einer optimalen kandidatenverbindung und verfahren dafür
EP26159568.0A Pending EP4723063A2 (de) 2016-09-30 2017-10-02 Computervorrichtung zur erkennung einer optimalen kandidatenverbindung und verfahren dafür

Family Applications Before (1)

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EP17787343.7A Active EP3520004B1 (de) 2016-09-30 2017-10-02 Computervorrichtung zur detektion einer optimalen kandidatenverbindung und verfahren dafür

Country Status (5)

Country Link
US (2) US11636924B2 (de)
EP (2) EP3520004B1 (de)
JP (2) JP7130630B2 (de)
CN (2) CN110140176B (de)
WO (1) WO2018060523A2 (de)

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WO2020081292A1 (en) 2018-10-17 2020-04-23 Becton, Dickinson And Company Adaptive sorting for particle analyzers
CN111291582B (zh) * 2020-03-04 2023-04-07 广西大学 一种基于水母群算法的rfid天线优化部署方法
CN114999582B (zh) * 2022-08-01 2022-10-04 乐比(广州)健康产业有限公司 一种驱蚊化合物含量检测方法
CN117116375B (zh) * 2023-08-22 2025-07-15 华东理工大学 一种混合样品组成部分的预测方法及系统

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Also Published As

Publication number Publication date
US20210005287A1 (en) 2021-01-07
JP7130630B2 (ja) 2022-09-05
EP3520004A2 (de) 2019-08-07
WO2018060523A2 (en) 2018-04-05
US20240013867A1 (en) 2024-01-11
JP2022141771A (ja) 2022-09-29
CN110140176A (zh) 2019-08-16
CN110140176B (zh) 2023-11-14
US11636924B2 (en) 2023-04-25
CN117457097A (zh) 2024-01-26
JP2019537102A (ja) 2019-12-19
US12308096B2 (en) 2025-05-20
WO2018060523A3 (en) 2018-06-14
EP3520004B1 (de) 2026-05-06

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