EP4728094A1 - Reagenz zur in-situ-hybridisierungsqualitätskontrolle - Google Patents
Reagenz zur in-situ-hybridisierungsqualitätskontrolleInfo
- Publication number
- EP4728094A1 EP4728094A1 EP24733920.3A EP24733920A EP4728094A1 EP 4728094 A1 EP4728094 A1 EP 4728094A1 EP 24733920 A EP24733920 A EP 24733920A EP 4728094 A1 EP4728094 A1 EP 4728094A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- sequence
- signal
- monitoring
- probe
- analyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363508732P | 2023-06-16 | 2023-06-16 | |
| PCT/EP2024/066706 WO2024256715A1 (en) | 2023-06-16 | 2024-06-16 | Reagent for in situ hybridization quality control |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP4728094A1 true EP4728094A1 (de) | 2026-04-22 |
Family
ID=91585544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24733920.3A Pending EP4728094A1 (de) | 2023-06-16 | 2024-06-16 | Reagenz zur in-situ-hybridisierungsqualitätskontrolle |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP4728094A1 (de) |
| WO (1) | WO2024256715A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025125442A1 (en) * | 2023-12-13 | 2025-06-19 | Resolve Biosciences Gmbh | High resolution multiplex method for detecting at least two targets |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007535944A (ja) | 2004-05-04 | 2007-12-13 | ヴェンタナ メディカル システムズ インコーポレイテッド | ｉｎｓｉｔｕハイブリダイゼーションのための内部対照 |
| US20210189475A1 (en) * | 2018-12-10 | 2021-06-24 | 10X Genomics, Inc. | Imaging system hardware |
| WO2020123316A2 (en) * | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Methods for determining a location of a biological analyte in a biological sample |
| EP3754028A1 (de) * | 2019-06-18 | 2020-12-23 | Apollo Life Sciences GmbH | Verfahren zur signalcodierung von analyten in einer probe |
| AU2020357801A1 (en) * | 2019-09-30 | 2022-04-14 | Yale University | Deterministic Barcoding for spatial omics sequencing |
| EP4484571A3 (de) * | 2020-02-21 | 2025-03-19 | 10X Genomics, Inc. | Verfahren und zusammensetzungen für integrierten räumlichen in-situ-assay |
| US12492427B2 (en) * | 2020-06-18 | 2025-12-09 | Resolve Biosciences Gmbh | Multiplex method for detecting different analytes in a sample |
| US20220042097A1 (en) * | 2020-08-04 | 2022-02-10 | The Broad Institute, Inc. | In-situ spatial transcriptomics and proteomics |
| KR20240046190A (ko) * | 2021-08-06 | 2024-04-08 | 리졸브 바이오사이언시즈 게엠베하 | 병원체 포함 샘플에서 분석물을 검출하는 방법 |
| EP4430206A1 (de) * | 2021-11-10 | 2024-09-18 | Encodia, Inc. | Verfahren zur barcodierung von makromolekülen in einzelnen zellen |
| US20240158836A1 (en) * | 2022-06-30 | 2024-05-16 | Resolve Biosciences Gmbh | High resolution multiplex method for detecting at least two targets with a distance of beyond the diffraction limit in a sample |
| WO2024002726A1 (en) * | 2022-06-30 | 2024-01-04 | Resolve Biosciences Gmbh | High resolution multiplex method for detecting at least two targets with a distance of beyond the diffraction limit in a sample |
-
2024
- 2024-06-16 WO PCT/EP2024/066706 patent/WO2024256715A1/en not_active Ceased
- 2024-06-16 EP EP24733920.3A patent/EP4728094A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024256715A1 (en) | 2024-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: UNKNOWN |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20260108 |
|
| AK | Designated contracting states |
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