EP4728518A1 - Procédé mis en oeuvre par ordinateur déterminant une valeur de charge allostatique d'un être humain - Google Patents

Procédé mis en oeuvre par ordinateur déterminant une valeur de charge allostatique d'un être humain

Info

Publication number
EP4728518A1
EP4728518A1 EP24732333.0A EP24732333A EP4728518A1 EP 4728518 A1 EP4728518 A1 EP 4728518A1 EP 24732333 A EP24732333 A EP 24732333A EP 4728518 A1 EP4728518 A1 EP 4728518A1
Authority
EP
European Patent Office
Prior art keywords
biomarker
allostatic load
cpg
value
phenotype
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24732333.0A
Other languages
German (de)
English (en)
Inventor
Sébastien NUSSLÉ
Semira GONSETH NUSSLÉ
Jonviea Danielle CHAMBERLAIN-CETTOU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genknowme SA
Original Assignee
Genknowme SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genknowme SA filed Critical Genknowme SA
Publication of EP4728518A1 publication Critical patent/EP4728518A1/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs

Landscapes

  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un procédé qui détermine une valeur de charge allostatique pour un être humain sur la base de la détermination de certains niveaux CpG d'un échantillon de cellule de cet être humain avec des connaissances concernant des niveaux CpG d'une population de référence, en particulier, sans avoir discuté avec ce sujet humain des problèmes de charge allostatique ou sans l'avoir testé à propos de valeurs du cœur ou de son sang sur le diabète, des problèmes de cholestérol, etc.
EP24732333.0A 2023-06-15 2024-06-17 Procédé mis en oeuvre par ordinateur déterminant une valeur de charge allostatique d'un être humain Pending EP4728518A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23179588 2023-06-15
PCT/EP2024/066814 WO2024256726A1 (fr) 2023-06-15 2024-06-17 Procédé mis en œuvre par ordinateur déterminant une valeur de charge allostatique d'un être humain

Publications (1)

Publication Number Publication Date
EP4728518A1 true EP4728518A1 (fr) 2026-04-22

Family

ID=86861813

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24732333.0A Pending EP4728518A1 (fr) 2023-06-15 2024-06-17 Procédé mis en oeuvre par ordinateur déterminant une valeur de charge allostatique d'un être humain

Country Status (2)

Country Link
EP (1) EP4728518A1 (fr)
WO (1) WO2024256726A1 (fr)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5912147A (en) 1996-10-22 1999-06-15 Health Research, Inc. Rapid means of quantitating genomic instability
AU7829398A (en) 1997-06-09 1998-12-30 University Of Southern California A cancer diagnostic method based upon dna methylation differences
DE19754482A1 (de) 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
EP0976835B1 (fr) 1998-07-29 2003-07-09 Keygene N.V. Méthode de détection de methylation des acides nucléiques par AFLP
US6605432B1 (en) 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
US6331393B1 (en) 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
EP1370685A2 (fr) 2000-04-06 2003-12-17 Epigenomics AG Diagnostic de maladies associees a la reparation de l'adn
AU2001276371A1 (en) 2000-06-30 2002-01-14 Epigenomics Ag Method and nucleic acids for analysing the methylation of genes implicated pharmacogenomics
US20050009059A1 (en) 2003-05-07 2005-01-13 Affymetrix, Inc. Analysis of methylation status using oligonucleotide arrays
US20050196792A1 (en) 2004-02-13 2005-09-08 Affymetrix, Inc. Analysis of methylation status using nucleic acid arrays
US20170251967A1 (en) 2016-03-04 2017-09-07 FlourishiQ Inc. System, apparatus and method for individualized stress management

Also Published As

Publication number Publication date
WO2024256726A1 (fr) 2024-12-19

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