EP4735880A2 - Composant de raccord d'extrémité destiné à être utilisé avec une colonne de chromatographie - Google Patents

Composant de raccord d'extrémité destiné à être utilisé avec une colonne de chromatographie

Info

Publication number
EP4735880A2
EP4735880A2 EP24846369.7A EP24846369A EP4735880A2 EP 4735880 A2 EP4735880 A2 EP 4735880A2 EP 24846369 A EP24846369 A EP 24846369A EP 4735880 A2 EP4735880 A2 EP 4735880A2
Authority
EP
European Patent Office
Prior art keywords
groove
end fitting
fitting component
central portion
frit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24846369.7A
Other languages
German (de)
English (en)
Inventor
Jason A. ANSPACH
Gareth FRIEDLANDER
Kenny A. Gallagher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phenomenex Inc
Original Assignee
Phenomenex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phenomenex Inc filed Critical Phenomenex Inc
Publication of EP4735880A2 publication Critical patent/EP4735880A2/fr
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6004Construction of the column end pieces
    • G01N30/6017Fluid distributors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6004Construction of the column end pieces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6004Construction of the column end pieces
    • G01N30/603Construction of the column end pieces retaining the stationary phase, e.g. Frits
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

L'invention concerne un composant de raccord d'extrémité destiné à être utilisé dans une colonne de chromatographie. Le composant de raccord d'extrémité a un corps et une partie centrale surélevée ayant au moins une ou plusieurs rainures à l'intérieur de celle-ci. Le composant de raccord d'extrémité est conçu pour venir en butée contre un ensemble fritté de la colonne de chromatographie. L'invention concerne également un dispositif de distribution de fluide, ayant un corps et une partie centrale surélevée avec au moins une ou plusieurs rainures. Le fluide entrant dans la colonne est distribué à travers la ou les rainures qui sont reliées à une ouverture centrale. Le fluide est distribué uniformément à travers la ou les rainures et à travers toute la surface d'une fritte d'une colonne. L'invention concerne également une colonne de chromatographie, ayant un composant de raccord d'extrémité.
EP24846369.7A 2023-07-27 2024-07-23 Composant de raccord d'extrémité destiné à être utilisé avec une colonne de chromatographie Pending EP4735880A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363515862P 2023-07-27 2023-07-27
PCT/US2024/039169 WO2025024453A2 (fr) 2023-07-27 2024-07-23 Composant de raccord d'extrémité destiné à être utilisé avec une colonne de chromatographie

Publications (1)

Publication Number Publication Date
EP4735880A2 true EP4735880A2 (fr) 2026-05-06

Family

ID=94375775

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24846369.7A Pending EP4735880A2 (fr) 2023-07-27 2024-07-23 Composant de raccord d'extrémité destiné à être utilisé avec une colonne de chromatographie

Country Status (2)

Country Link
EP (1) EP4735880A2 (fr)
WO (1) WO2025024453A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140124444A1 (en) * 2012-11-06 2014-05-08 Phenomenex, Inc. Sintered metal fiber disks for chromatographic applications
SG11201808869WA (en) * 2016-04-08 2018-11-29 Gore & Ass Affinity chromatography devices
GB201700019D0 (en) * 2017-01-01 2017-02-15 Ion Science Ltd Gas detection apparatus

Also Published As

Publication number Publication date
WO2025024453A3 (fr) 2025-04-17
WO2025024453A2 (fr) 2025-01-30

Similar Documents

Publication Publication Date Title
US5482628A (en) Column for liquid chromatography
US5651885A (en) Column for liquid chromatography
EP2969460B1 (fr) Raccord à renfort structurel et passage de fluide biocompatible
EP0713416B1 (fr) Raccord integral et filtre
US8696038B2 (en) Flat bottom fitting assembly
JP2015512053A (ja) トルク制限接続具
JP2020503477A (ja) 多部品ステータアセンブリを伴う高圧弁
JP2014515480A (ja) 分解能を向上させたクロマトグラフィの方法および装置
US20080029449A1 (en) Graded external prefilter element for continuous-flow systems
US20050077222A1 (en) Sealed integral liquid chromatography system
US20130256231A1 (en) Device, Apparatus And Method For Performing Separations
JP2014517924A (ja) 分解能を向上させたクロマトグラフィの方法および装置
EP4735880A2 (fr) Composant de raccord d'extrémité destiné à être utilisé avec une colonne de chromatographie
EP1635173B1 (fr) Colonne avec pièce intermédiaire conique
JPH09119924A (ja) クロマトグラフィー用分離カラム
US20190070524A1 (en) Devices, systems, and methods for splitting fluid flows with porous media
JP7273147B2 (ja) 圧縮限定アセンブリを有するカラム
WO2011061769A1 (fr) Dispositifs de support pour colonnes capillaires et nano-colonnes de clhp
US20250052729A1 (en) Biocompatible fitting assembly and fluidic connection system
WO2025122540A1 (fr) Colonnes courtes connectées en série pour des bioséparations
AU2003201392A1 (en) Sealed integral liquid chromatography sytem

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE