EP4762061A1 - Thiénothiadiazines, leur préparation et leur application thérapeutique - Google Patents

Thiénothiadiazines, leur préparation et leur application thérapeutique

Info

Publication number
EP4762061A1
EP4762061A1 EP24758485.7A EP24758485A EP4762061A1 EP 4762061 A1 EP4762061 A1 EP 4762061A1 EP 24758485 A EP24758485 A EP 24758485A EP 4762061 A1 EP4762061 A1 EP 4762061A1
Authority
EP
European Patent Office
Prior art keywords
alkyl
compound
chloro
formula
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24758485.7A
Other languages
German (de)
English (en)
Inventor
Lothar Schwink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of EP4762061A1 publication Critical patent/EP4762061A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés de formule (I), ou un énantiomère, un diastéréoisomère, un tautomère ou un atropisomère de ceux-ci, ou un mélange de ceux-ci, ou un sel pharmaceutiquement acceptable de ceux-ci, R1, R2, R3, R4, R5, A et n étant tels que définis dans la description. L'invention concerne également des procédés de préparation de tels composés, et des compositions pharmaceutiques comprenant de tels composés. Ces composés sont utiles dans le traitement de troubles inflammatoires, de troubles allergiques, de troubles cutanés, de troubles mastocytaires, de troubles de la douleur et de troubles de démangeaisons.
EP24758485.7A 2023-08-17 2024-08-19 Thiénothiadiazines, leur préparation et leur application thérapeutique Pending EP4762061A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23306384 2023-08-17
PCT/EP2024/073179 WO2025037034A1 (fr) 2023-08-17 2024-08-19 Thiénothiadiazines, leur préparation et leur application thérapeutique

Publications (1)

Publication Number Publication Date
EP4762061A1 true EP4762061A1 (fr) 2026-06-24

Family

ID=87971876

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24758485.7A Pending EP4762061A1 (fr) 2023-08-17 2024-08-19 Thiénothiadiazines, leur préparation et leur application thérapeutique

Country Status (3)

Country Link
EP (1) EP4762061A1 (fr)
CN (1) CN121712780A (fr)
WO (1) WO2025037034A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ220498A3 (cs) * 1996-01-17 1998-11-11 Novo Nordisk A/S Deriváty 1,2,4-thiadiazinu a 1,4-thiazinu, příprava a použití
JP7574215B2 (ja) * 2019-04-29 2024-10-28 ソレント セラピューティクス，エルエルシー ＭＲＧＸ２の阻害薬である３－アミノ－４Ｈ－ベンゾ［ｅ］［１，２，４］チアジアジン１，１－ジオキシド誘導体

Also Published As

Publication number Publication date
WO2025037034A1 (fr) 2025-02-20
CN121712780A (zh) 2026-03-20

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