ES2000030A6 - Metodo de purificar factor sanguineo viii:c - Google Patents

Metodo de purificar factor sanguineo viii:c

Info

Publication number
ES2000030A6
ES2000030A6 ES8600222A ES8600222A ES2000030A6 ES 2000030 A6 ES2000030 A6 ES 2000030A6 ES 8600222 A ES8600222 A ES 8600222A ES 8600222 A ES8600222 A ES 8600222A ES 2000030 A6 ES2000030 A6 ES 2000030A6
Authority
ES
Spain
Prior art keywords
factor viii
purifying factor
purifying
proteins
potency
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600222A
Other languages
English (en)
Inventor
David L Farb
Ricardo H Landaburu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Publication of ES2000030A6 publication Critical patent/ES2000030A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE REVELA UN METODO PARA PURIFICAR FACTOR VIII:C CON ALTO RENDIMIENTO Y POTENCIA A PARTIR DE MATERIAL DE FUENTE QUE CONTIENE FACTOR VIII:C,FACTOR VIII:R Y OTRAS PROTEINAS Y FACTORES DEL PLASMA, EL CUAL PROCEDIMIENTO COMPRENDE LAS ETAPAS DE: ABSORBER FACTOR VIII:C EN UNA MATRIZ DE INTERACCION HIDROFOBA, SEPARAR LAS PROTEINAS NO DESEADAS DEL FACTOR VIII:C Y ELUDIR FACTOR VIII:C POR MEDIO DE UNA DISOLUCION.
ES8600222A 1985-07-11 1986-07-10 Metodo de purificar factor sanguineo viii:c Expired ES2000030A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/753,822 US4758657A (en) 1985-07-11 1985-07-11 Method of purifying Factor VIII:C

Publications (1)

Publication Number Publication Date
ES2000030A6 true ES2000030A6 (es) 1987-10-01

Family

ID=25032302

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600222A Expired ES2000030A6 (es) 1985-07-11 1986-07-10 Metodo de purificar factor sanguineo viii:c

Country Status (6)

Country Link
US (1) US4758657A (es)
EP (1) EP0209041A3 (es)
JP (1) JPS6219534A (es)
AU (1) AU6001586A (es)
DK (1) DK332086A (es)
ES (1) ES2000030A6 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043428A (en) * 1984-08-31 1991-08-27 Behringwerke Aktiengesellschaft Pasteurized, isoagglutinin-free factor VIII preparation and a process for its production
WO1988005825A1 (en) * 1987-01-30 1988-08-11 Biogen N.V. A method for producing factor viii in high yield
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
US5605884A (en) * 1987-10-29 1997-02-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Factor VIII formulations in high ionic strength media
ATE112287T1 (de) * 1987-12-21 1994-10-15 Miles Inc Faktor viii- gelfiltration.
DK162233C (da) * 1989-11-09 1992-03-16 Novo Nordisk As Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
FR2681867B1 (fr) 1991-09-26 1993-12-31 Pasteur Merieux Serums Vaccins Procede de purification du facteur viii et preparations obtenues.
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
WO1993022336A1 (en) * 1992-04-30 1993-11-11 Alpha Therapeutic Corporation Improved solubilization and stabilization of factor viii complex
DE69329795T2 (de) * 1992-10-02 2001-07-05 Genetics Institute, Inc. Zusammensetzung, welche den koagulationsfaktor viii beinhaltet; verfahren zu deren herstellung und die benutzung eines oberflächenaktiven stoffes als stabilisator
WO1995003332A1 (en) * 1993-07-23 1995-02-02 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
SE503424C2 (sv) * 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
GB9501040D0 (en) * 1995-01-19 1995-03-08 Quadrant Holdings Cambridge Dried composition
US7253262B2 (en) * 1995-01-19 2007-08-07 Quandrant Drug Delivery Limited Dried blood factor composition comprising trehalose
US7244824B2 (en) * 1995-01-19 2007-07-17 Quadrant Drug Delivery Limited Dried blood factor composition comprising trehalose
US5925738A (en) * 1995-12-01 1999-07-20 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US5763401A (en) * 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
FR2772381B1 (fr) † 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
EP2921180B1 (en) 1999-02-22 2019-08-14 University of Connecticut Albumin-free factor VIII formulations
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
SI2674037T1 (sl) * 2009-01-26 2016-02-29 Burcon Nutrascience (Mb) Corp., Proizvodnja topnega sojinega proteinskega proizvoda iz sojine proteinske micelarne mase ("S200Ca")

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069216A (en) * 1975-06-16 1978-01-17 Edward Shanbrom, Inc. Simplified methods for preparation of very high purity Factor VIII concentrate
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4673733A (en) * 1985-04-11 1987-06-16 Sudhish Chandra Treatment of biological and pharmaceutical products adsorbed on a solid phase with virus and pyrogen inactivating agents

Also Published As

Publication number Publication date
JPS6219534A (ja) 1987-01-28
EP0209041A2 (en) 1987-01-21
EP0209041A3 (en) 1989-03-22
DK332086A (da) 1987-01-12
US4758657A (en) 1988-07-19
AU6001586A (en) 1987-01-15
DK332086D0 (da) 1986-07-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981001