ES2000060A6 - Procedimiento de hidroxilacion por via mecrobiologica de quinina, quinidina y derivados - Google Patents
Procedimiento de hidroxilacion por via mecrobiologica de quinina, quinidina y derivadosInfo
- Publication number
- ES2000060A6 ES2000060A6 ES8600486A ES8600486A ES2000060A6 ES 2000060 A6 ES2000060 A6 ES 2000060A6 ES 8600486 A ES8600486 A ES 8600486A ES 8600486 A ES8600486 A ES 8600486A ES 2000060 A6 ES2000060 A6 ES 2000060A6
- Authority
- ES
- Spain
- Prior art keywords
- quinidine
- quinine
- aspergilus
- hydroxylation
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 title abstract 6
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 title abstract 4
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 title abstract 3
- 229960001404 quinidine Drugs 0.000 title abstract 3
- 230000033444 hydroxylation Effects 0.000 title abstract 2
- 238000005805 hydroxylation reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 235000001258 Cinchona calisaya Nutrition 0.000 title 1
- 229960000948 quinine Drugs 0.000 title 1
- 241001290628 Cunninghamella echinulata Species 0.000 abstract 1
- 241000223211 Curvularia lunata Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 241000306281 Mucor ambiguus Species 0.000 abstract 1
- 241000378863 Mucor plumbeus Species 0.000 abstract 1
- 241000228143 Penicillium Species 0.000 abstract 1
- 241000187419 Streptomyces rimosus Species 0.000 abstract 1
- 238000010564 aerobic fermentation Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/931—Mucor
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
ESTA INVENCION SE RELACIONA CON LA PREPARACION DE DERIVADOS HIDROXILADOS DE QUININA Y QUINIDINA. EL PROCEDIMIENTO CONSISTEEN HACER ACTUAR UN MICROORGANISMO DEL TIPO HONGO INFERIOR, SELECCIONADO ENTRE EL GRUPO CONSTITUIDO POR EL ASPERGILUS FLAVUS, ASPERGILUS OCHRACEUS, ASPERGILUS NIGER, CUNNINGHAMELLA ECHINULATA, CURVULARIA LUNATA, MUCOR CIRCINELLOIDES, MUCOR PLUMBEUS, PENICILLIUM URPUROGEUM Y RHIZOPUS ARRHIZUS O DEL TIPI BACTERIANO, TAL COMO EL STREPTOMYCES RIMOSUS, SOBRE EL COMPUESTO A HIDROLIZAR, EN CONDICIONES DE FERMENTACION AEROBICA, EN CULTIVO SUMERGIDO. APLICACION A LA HIDROXILACION REGIOESPECIFICA Y ESTEREOESPECIFICA DE LA QUINIDINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8511221A FR2585366B1 (fr) | 1985-07-23 | 1985-07-23 | Procede d'hydroxylation par voie microbiologique de la quinine, de la quinidine, et de derives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000060A6 true ES2000060A6 (es) | 1987-11-16 |
Family
ID=9321539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8600486A Expired ES2000060A6 (es) | 1985-07-23 | 1986-07-22 | Procedimiento de hidroxilacion por via mecrobiologica de quinina, quinidina y derivados |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4996149A (es) |
| EP (1) | EP0231234B1 (es) |
| JP (1) | JPS63500563A (es) |
| CA (1) | CA1276577C (es) |
| DE (1) | DE3672475D1 (es) |
| DK (1) | DK138087A (es) |
| ES (1) | ES2000060A6 (es) |
| FI (1) | FI871191A0 (es) |
| FR (1) | FR2585366B1 (es) |
| GR (1) | GR861918B (es) |
| HU (1) | HU201355B (es) |
| IL (1) | IL79484A (es) |
| PT (1) | PT83047B (es) |
| WO (1) | WO1987000552A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187074A (en) * | 1990-10-11 | 1993-02-16 | Merck & Co., Inc. | Method of hydroxylation with ATCC 55086 |
| US5192668A (en) * | 1990-10-11 | 1993-03-09 | Merck & Co., Inc. | Synthesis of protease inhibitor |
| DE4034218A1 (de) * | 1990-10-27 | 1992-04-30 | Merck Patent Gmbh | Verfahren zur herstellung von carebastin |
| FI915231A7 (fi) * | 1990-11-08 | 1992-05-09 | Lonza Ag | Mikrobiologinen menetelmä hydroksyloitujen pyratsiinijohdannaisten valmistamiseksi |
| US5356624A (en) * | 1993-04-23 | 1994-10-18 | The United States Of America As Represented By The Secretary Of Agriculture | Biological treatment for controlling wood deteriorating fungi |
| US20040259217A1 (en) * | 2003-06-19 | 2004-12-23 | Prabha Devi | Plant mangrove-associated fungus Culvularia lunata and a simple and efficient method of obtaining high yield of pure mannitol from the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2506312A1 (fr) * | 1981-05-20 | 1982-11-26 | Nativelle Sa Ets | Nouveaux derives de la quinidine, procede de preparation et application en therapeutique |
-
1985
- 1985-07-23 FR FR8511221A patent/FR2585366B1/fr not_active Expired
-
1986
- 1986-07-21 IL IL79484A patent/IL79484A/xx unknown
- 1986-07-22 DE DE8686904226T patent/DE3672475D1/de not_active Expired - Fee Related
- 1986-07-22 HU HU863555A patent/HU201355B/hu unknown
- 1986-07-22 US US07/037,351 patent/US4996149A/en not_active Expired - Fee Related
- 1986-07-22 JP JP61504099A patent/JPS63500563A/ja active Pending
- 1986-07-22 CA CA000514383A patent/CA1276577C/fr not_active Expired - Fee Related
- 1986-07-22 ES ES8600486A patent/ES2000060A6/es not_active Expired
- 1986-07-22 FI FI871191A patent/FI871191A0/fi not_active Application Discontinuation
- 1986-07-22 GR GR861918A patent/GR861918B/el unknown
- 1986-07-22 EP EP86904226A patent/EP0231234B1/fr not_active Expired - Lifetime
- 1986-07-22 WO PCT/FR1986/000260 patent/WO1987000552A1/fr not_active Ceased
- 1986-07-23 PT PT83047A patent/PT83047B/pt not_active IP Right Cessation
-
1987
- 1987-03-18 DK DK138087A patent/DK138087A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI871191A7 (fi) | 1987-03-18 |
| PT83047B (pt) | 1988-07-01 |
| IL79484A (en) | 1990-03-19 |
| DK138087D0 (da) | 1987-03-18 |
| EP0231234B1 (fr) | 1990-07-04 |
| FI871191L (fi) | 1987-03-18 |
| HUT43638A (en) | 1987-11-30 |
| DK138087A (da) | 1987-03-18 |
| CA1276577C (fr) | 1990-11-20 |
| PT83047A (fr) | 1986-08-01 |
| JPS63500563A (ja) | 1988-03-03 |
| HU201355B (en) | 1990-10-28 |
| EP0231234A1 (fr) | 1987-08-12 |
| WO1987000552A1 (fr) | 1987-01-29 |
| IL79484A0 (en) | 1986-10-31 |
| FI871191A0 (fi) | 1987-03-18 |
| DE3672475D1 (de) | 1990-08-09 |
| GR861918B (en) | 1986-11-24 |
| FR2585366B1 (fr) | 1987-09-11 |
| US4996149A (en) | 1991-02-26 |
| FR2585366A1 (fr) | 1987-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-07-22 |
|
| FD1A | Patent lapsed |
Effective date: 20001009 |