ES2000065A6 - Procedimiento para la preparacion de una vacuna contral la rabia - Google Patents

Procedimiento para la preparacion de una vacuna contral la rabia

Info

Publication number
ES2000065A6
ES2000065A6 ES8600731A ES8600731A ES2000065A6 ES 2000065 A6 ES2000065 A6 ES 2000065A6 ES 8600731 A ES8600731 A ES 8600731A ES 8600731 A ES8600731 A ES 8600731A ES 2000065 A6 ES2000065 A6 ES 2000065A6
Authority
ES
Spain
Prior art keywords
viruses
vaccine
rabies
nerve tissue
embryos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600731A
Other languages
English (en)
Inventor
Reinhard Gluck
Rene Germanier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten filed Critical Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Publication of ES2000065A6 publication Critical patent/ES2000065A6/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/205Rhabdoviridae, e.g. rabies virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

ES OBJETO DEL INVENTO UN PROCEDIMIENTO PARA LA PREPARACION DEUNA VACUNA CONTRA LA RABIA POR REPRODUCCION DE VIRUS DE RABIAEN TEJIDO NERVIOSO DE ANIMALES, PREDOMINANTEMENTE EN EMBRIONES DE AVES DE CORRAL, COSECHA DE LOS VIRUS A PARTIR DEL TEJIDONERVIOSO O A PARTIR DE LAS CABEZAS DE EMBRIONES, ENRIQUECIMIENTO DE LOS VIRUS, INACTIVACION DE LOS MISMOS Y CONFECCION PARA FORMAR LA VACUNA, EL CUAL PROCEDIMIENTO ESTA CARACTERIZADO PORQUE DURANTE LA COSECHA DE LOS VIRUS SE EVITA LA HOMOGENEIZACION DEL TEJIDO NERVIOSO O DE LAS CABEZAS DE EMBRIONES CON UN MEZCLADOR Y CON ELLO SE IMPIDE EL LESIONAMIENTO Y EL DESPEDAZAMIENTO DE LOS VIRUS, DESMENUZANDO DE MODO MODERADO PARA LAS CELULAS EL TEJIDO NERVIOSO O LAS CABEZAS DE LOS EMBRIONES OBIEN SU CONTENIDO, EXTRAYENDO POR LAVADO, A PARTIR DE LA SUSPENSION DE CELULAS OBTENIDAS, LOS VIRUS COMPLETOS, VIVOS Y CAPACES DE REPRODUCCION CONCENTRANDO LA SUSPENSION DE VIRUS OBTENIDA, DESLIPIDANDO POR EXTRACCION CON UN DISOLVENTE ORGANICO NO MISCIBLE CON AGUA, Y DESPUES DE ELLO CONCENTRANDO SELECTIVAMENTE DE MODO ADICIONAL. EL INVENTO CONCIERNE, ADEMAS DE ELLO, A UNA VACUNA CONTRA LA RABIA, EXENTA DE MIELINA, LA CUAL ESTA CARACTERIZADA PORQUE SE HABIA OBTENIDO A PARTIR DE TEJIDODE CABEZA DE EMBRION DE AVE DE CORRAL, QUE CONTIENE VIRUS DE RABIA, DE ACUERDO CON EL PROCEDIMIENTO ANTES EXPLICADO.
ES8600731A 1985-11-22 1986-07-30 Procedimiento para la preparacion de una vacuna contral la rabia Expired ES2000065A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH499985 1985-11-22

Publications (1)

Publication Number Publication Date
ES2000065A6 true ES2000065A6 (es) 1987-11-16

Family

ID=4286207

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600731A Expired ES2000065A6 (es) 1985-11-22 1986-07-30 Procedimiento para la preparacion de una vacuna contral la rabia

Country Status (9)

Country Link
EP (1) EP0222974B1 (es)
JP (1) JPS62129225A (es)
AT (1) ATE69383T1 (es)
AU (1) AU593041B2 (es)
CA (1) CA1271708A (es)
DE (1) DE3682482D1 (es)
ES (1) ES2000065A6 (es)
PT (1) PT83543B (es)
ZA (1) ZA866846B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN030794A0 (en) 1994-12-22 1995-01-27 Aruba International Pty Ltd Discontinuous plasma or serum delipidation
AUPQ486699A0 (en) * 1999-12-23 2000-02-03 Aruba International Pty Ltd A method of treating infectious diseases
WO2005016246A2 (en) * 2003-06-20 2005-02-24 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content useful for treating and preventing infectious diseases
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US7439052B2 (en) 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
US7407662B2 (en) 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
US20090017069A1 (en) 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7407663B2 (en) 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US6991727B2 (en) 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US7033500B2 (en) 2001-06-25 2006-04-25 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
US20060060520A1 (en) 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
US7393826B2 (en) 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
CA2531227A1 (en) 2003-07-03 2005-02-10 Lipid Sciences Inc. Methods and apparatus for creating particle derivatives of hdl with reduced lipid content
CA3083194A1 (en) 2017-11-22 2019-05-31 Hdl Therapeutics, Inc. Systems and methods for priming fluid circuits of a plasma processing system
AU2018396009A1 (en) 2017-12-28 2020-07-16 Hdl Therapeutics, Inc. Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3143470A (en) * 1961-04-24 1964-08-04 Parke Davis & Co Rabies virus propagation in embryonic cells maintained in a medium containing pancreatic digest of casein
CH638985A5 (de) * 1979-04-10 1983-10-31 Schweiz Serum & Impfinst Verfahren zur herstellung eines tollwutimpfstoffes und danach erhaltener impfstoff.
US4347239A (en) * 1980-07-30 1982-08-31 Norden Laboratories, Inc. Inactivated rabies vaccine for veterinary use

Also Published As

Publication number Publication date
JPS62129225A (ja) 1987-06-11
CA1271708A (en) 1990-07-17
ZA866846B (en) 1987-04-29
AU6563086A (en) 1987-05-28
DE3682482D1 (de) 1991-12-19
PT83543B (pt) 1988-11-30
EP0222974B1 (de) 1991-11-13
JPH0586934B2 (es) 1993-12-14
AU593041B2 (en) 1990-02-01
EP0222974A3 (en) 1989-06-14
PT83543A (fr) 1986-11-01
EP0222974A2 (de) 1987-05-27
ATE69383T1 (de) 1991-11-15

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