ES2000398A6 - Un procedimiento para la preparacion de una composicion para aplicacion topica para utilizar en la prevencion de ulceras de presion - Google Patents
Un procedimiento para la preparacion de una composicion para aplicacion topica para utilizar en la prevencion de ulceras de presionInfo
- Publication number
- ES2000398A6 ES2000398A6 ES8601952A ES8601952A ES2000398A6 ES 2000398 A6 ES2000398 A6 ES 2000398A6 ES 8601952 A ES8601952 A ES 8601952A ES 8601952 A ES8601952 A ES 8601952A ES 2000398 A6 ES2000398 A6 ES 2000398A6
- Authority
- ES
- Spain
- Prior art keywords
- topical application
- pharmaceutical composition
- compositions
- nicotinate
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000699 topical effect Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- -1 nicotinate ester Chemical class 0.000 abstract 2
- 206010011985 Decubitus ulcer Diseases 0.000 abstract 1
- 206010015150 Erythema Diseases 0.000 abstract 1
- 208000004210 Pressure Ulcer Diseases 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 231100000321 erythema Toxicity 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- RVYGVBZGSFLJKH-UHFFFAOYSA-N hexyl pyridine-3-carboxylate Chemical compound CCCCCCOC(=O)C1=CC=CN=C1 RVYGVBZGSFLJKH-UHFFFAOYSA-N 0.000 abstract 1
- 229940051295 hexylnicotinate Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION PARA APLICACION TOPICA UTIL PARA PREVENIR LAS ULCERAS DE PRESION INCLUYENDO UN ESTER DE TIPO NICOTINATO QUE ACTUA LENTAMENTE, V.G., NICOTINATO DE HEXILO, EN UNA CONCENTRACION Y FORMULACION INSUFICIENTEMENTE PARA CAUSAR ERITEMA OBSERVABLE PERO SUFICIENTE PARA FACILITAR EL FLUJO SANGUINEO PERIFERICO. LA COMPOSICION PUEDE COMPRENDER TAMBIEN INGREDIENTES HABITUALES EN LAS COMPOSICIONES PARA APLICACION TOPICA A LA PIEL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858523036A GB8523036D0 (en) | 1985-09-18 | 1985-09-18 | Pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000398A6 true ES2000398A6 (es) | 1988-02-16 |
Family
ID=10585343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8601952A Expired ES2000398A6 (es) | 1985-09-18 | 1986-09-17 | Un procedimiento para la preparacion de una composicion para aplicacion topica para utilizar en la prevencion de ulceras de presion |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0220825B1 (es) |
| AT (1) | ATE46083T1 (es) |
| DE (1) | DE3665403D1 (es) |
| ES (1) | ES2000398A6 (es) |
| GB (2) | GB8523036D0 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU87390A1 (fr) * | 1988-11-17 | 1990-06-12 | Oreal | Utilisation du nicotinate d'alpha-tocopherol et/ou du nicotinate d'hexyle dans une composition cosmetique a action amincissante |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2431558A (en) * | 1945-05-22 | 1947-11-25 | Winthrop Stearns Inc | Vasodilator compositions comprising alkyl nicotinates |
| GB620687A (en) * | 1945-05-22 | 1949-03-29 | Winthrop Chem Co Inc | Improvements in or relating to alkyl esters of nicotinic acid |
| FR1593M (fr) * | 1960-11-16 | 1962-12-03 | Kabi Ab | Compositions pour le traitement de l'acne. |
-
1985
- 1985-09-18 GB GB858523036A patent/GB8523036D0/en active Pending
-
1986
- 1986-09-17 ES ES8601952A patent/ES2000398A6/es not_active Expired
- 1986-09-18 EP EP86307195A patent/EP0220825B1/en not_active Expired
- 1986-09-18 AT AT86307195T patent/ATE46083T1/de active
- 1986-09-18 DE DE8686307195T patent/DE3665403D1/de not_active Expired
- 1986-09-18 GB GB8622487A patent/GB2184652B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0220825A3 (en) | 1987-09-09 |
| GB8523036D0 (en) | 1985-10-23 |
| ATE46083T1 (de) | 1989-09-15 |
| GB8622487D0 (en) | 1986-10-22 |
| EP0220825A2 (en) | 1987-05-06 |
| EP0220825B1 (en) | 1989-09-06 |
| DE3665403D1 (en) | 1989-10-12 |
| GB2184652B (en) | 1989-08-23 |
| GB2184652A (en) | 1987-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-09-17 |