ES2000602A6 - Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina - Google Patents

Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina

Info

Publication number
ES2000602A6
ES2000602A6 ES8600959A ES8600959A ES2000602A6 ES 2000602 A6 ES2000602 A6 ES 2000602A6 ES 8600959 A ES8600959 A ES 8600959A ES 8600959 A ES8600959 A ES 8600959A ES 2000602 A6 ES2000602 A6 ES 2000602A6
Authority
ES
Spain
Prior art keywords
related peptide
peptide derivatives
calcitonin gene
gene related
asn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600959A
Other languages
English (en)
Inventor
Toshiharj Noda
Nobutaka Fujii
Kaorj Morita
Masayuki Hori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of ES2000602A6 publication Critical patent/ES2000602A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57527—Calcitonin gene related peptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS PEPTIDOS RELACIONADOS CON LA CALCITONINA. COMPRENDE SOMETER A CONDENSACION, POR LA TECNICA DE LA FASE LIQUIDA Y/O DE LA FASE SOLIDA LOS CORRESPONDIENTES AMINOACIDOS O PEPTIDOS PARCIALES CONSTITUTIVOS DEL PEPTIDO, SEGUIDO DE ELIMINACION DE LOS GRUPOS PROTECTORES MEDIANTE HIDROLISIS, DESCOMPOSICION CON ACIDO, REDUCCION, AMINOLISIS O HIDROGENOLISIS. ESTOS PEPTIDOS SON UTILES COMO MEDICINAS O AUXILIARES DE DIAGNOSTICO CLINICO PARA EL METABOLISMO DE LOS HUESOS Y EL SISTEMA NERVIOSO CENTRAL.
ES8600959A 1985-08-09 1986-08-08 Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina Expired ES2000602A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17534085 1985-08-09

Publications (1)

Publication Number Publication Date
ES2000602A6 true ES2000602A6 (es) 1988-03-01

Family

ID=15994349

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600959A Expired ES2000602A6 (es) 1985-08-09 1986-08-08 Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina

Country Status (5)

Country Link
US (1) US4743677A (es)
EP (1) EP0212432B1 (es)
JP (1) JPS62129297A (es)
DE (1) DE3685167D1 (es)
ES (1) ES2000602A6 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052583T3 (es) * 1986-12-04 1994-07-16 Asahi Chemical Ind Derivados de peptidos relacionados con el gel calcitonina.
JPS6426598A (en) * 1987-07-22 1989-01-27 Toyo Jozo Kk Calcitonin gene related peptide derivative
JPH02262595A (ja) * 1988-02-29 1990-10-25 Otsuka Pharmaceut Co Ltd ポリペプチド誘導体
EP0367463A1 (en) * 1988-10-20 1990-05-09 Celltech Limited Calcitonin gene related peptide analogues
DE3943519A1 (de) * 1989-04-27 1991-01-17 Stief Georg Arzneimittel zur behandlung erektiler dysfunktionen
GB8915712D0 (en) * 1989-07-08 1989-08-31 Macintyre Iain Medical treatment
KR920701248A (ko) * 1989-11-08 1992-08-11 고지마 아끼로 펩티드, 및 환상 펩티드의 제조 방법
EP0579611A4 (en) * 1991-02-12 1995-04-19 Luminis Pty Ltd Peptides.
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
WO1992015317A1 (en) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Synthetic preparation of amylin and amylin analogues
WO1996029343A1 (en) * 1995-03-20 1996-09-26 Kyowa Hakko Kogyo Co., Ltd. Novel calcitonin derivatives
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
WO1998001133A1 (en) * 1996-07-08 1998-01-15 Yamanouchi Pharmaceutical Co., Ltd. Bone resorption inhibitors
US20010046955A1 (en) * 2000-03-14 2001-11-29 Gelfand Erwin W. Method for reducing allergen-induced airway hyperresponsiveness
KR100418962B1 (ko) * 2001-06-07 2004-02-14 김학주 2-(4-나이트로페닐설포닐)에톡시카르보닐-아미노산류를사용하여 펩티드를 고수율 및 고순도로 제조하는 방법
SI3045182T1 (en) 2005-11-14 2018-08-31 Teva Pharmaceuticals International Gmbh An antibody to a peptide-associated peptide antagonist to calcitonin for treating a headache in aggregates
KR101304150B1 (ko) 2008-03-04 2013-09-05 라브리스 바이올로직스 인코포레이티드 만성 통증의 치료 방법
BR112012004464B8 (pt) 2009-08-28 2021-05-25 Labrys Biologics Inc uso de um anticorpo antagonista anti-cgrp para preparar uma composição farmacêutica para tratar e/ou prevenir dor visceral e/ou um ou mais sintomas de dor visceral, em que a dor visceral está associada á cistite intersticial (ic), e dita composição farmacêutica
EA033109B1 (ru) 2011-05-20 2019-08-30 Олдербайо Холдингз Ллк Способы ингибирования, профилактики или лечения диареи и/или поддержания соответствующих уровней электролитов и жидкости в толстой кишке субъекта, подвергающегося связанному с диареей состоянию, с помощью антитела против cgrp или фрагмента антитела против cgrp
CN108014334B (zh) 2011-05-20 2021-11-30 H.伦德贝克公司 抗cgrp抗体和抗体片段用于在有需要的受试者中预防或抑制畏光或厌光的用途
PT3495392T (pt) 2011-05-20 2021-09-22 H Lundbeck As Composições anti-cgrp e a sua utilização
EP2807187B1 (en) * 2012-01-26 2017-07-26 Christopher J. Soares Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use
US20170114122A1 (en) 2015-10-23 2017-04-27 Alderbio Holdings Llc Regulation of glucose metabolism using anti-cgrp antibodies
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
MX378344B (es) 2014-03-21 2025-03-10 Teva Pharmaceuticals Int Gmbh Anticuerpos antagonistas dirigidos contra el peptido relacionado con el gen de calcitonina y metodos que usan los mismos.
JP7123932B2 (ja) 2016-09-02 2022-08-23 クリストファー ジェイ． ソアレス 神経保護及び神経疾患におけるｃｇｒｐ受容体アンタゴニストの使用
SMT202600087T1 (it) 2016-09-23 2026-03-09 Teva Pharmaceuticals Int Gmbh Trattamento dell’emicrania refrattaria
CN109406709B (zh) * 2018-12-27 2020-11-10 福建省中医药研究院(福建省青草药开发服务中心） 一种太子参药材中氨基酸类成分的薄层鉴别方法
CR20210373A (es) 2019-01-08 2021-08-19 H Lundbeck As Tratamiento agudo y tratamiento rápido de la cefalea usando anticuerpos anti-cgrp
GEAP202515803A (en) 2019-05-02 2025-06-10 H Lundbeck As Treatment of headache using anti-cgrp antibodies
KR20210124867A (ko) 2020-04-06 2021-10-15 하. 룬드벡 아크티에셀스카브 항-cgrp 항체를 사용하는 편두통 관련 성가심 증상 (mbs) 의 치료

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514331A (en) * 1983-06-29 1985-04-30 University Patents, Inc. Peptide hormones with calcitonin-like activity
US4549986A (en) * 1983-12-23 1985-10-29 The Salk Institute For Biological Studies Human CGRP

Also Published As

Publication number Publication date
EP0212432A2 (en) 1987-03-04
US4743677A (en) 1988-05-10
EP0212432A3 (en) 1989-01-25
JPS62129297A (ja) 1987-06-11
DE3685167D1 (de) 1992-06-11
EP0212432B1 (en) 1992-05-06

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Owner name: ASAHI KASEI KABUSHIKI KAISHA