ES2001292A6 - Procedimiento para preparar hexahidro-1,2,4-triazin-3,5-dionas substituidas - Google Patents
Procedimiento para preparar hexahidro-1,2,4-triazin-3,5-dionas substituidasInfo
- Publication number
- ES2001292A6 ES2001292A6 ES8601669A ES8601669A ES2001292A6 ES 2001292 A6 ES2001292 A6 ES 2001292A6 ES 8601669 A ES8601669 A ES 8601669A ES 8601669 A ES8601669 A ES 8601669A ES 2001292 A6 ES2001292 A6 ES 2001292A6
- Authority
- ES
- Spain
- Prior art keywords
- cycloalkyl
- alkyl
- compounds
- diones
- hexahydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HUQXVCMANCHPAD-UHFFFAOYSA-N 2-phenyl-1,2,4-triazinane-3,5-dione Chemical class O=C1NC(=O)CNN1C1=CC=CC=C1 HUQXVCMANCHPAD-UHFFFAOYSA-N 0.000 title 1
- -1 benzylsulfinyl Chemical group 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 230000002192 coccidiostatic effect Effects 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Seasonings (AREA)
Abstract
SE OBTIENEN COMPUESTOS DE FORMULA I EN QUE N, R1, R2 Y R3 TIENEN LOS SIGNIFICADOS INDICADOS EN LA MEMORIA MEDIANTE ALQUILACION O ACILACION DE UN COMPUESTO II EN QUE R1 ES COMO ANTES SE HA DEFINIDO, CON COMPUESTOS R3X(X=GRUPO LABIL) O R2Y(Y=GRUPO LABIL), ESTANDO DEFINIDOS R2 Y R3 COMO ANTES SE INDICA. LOS COMPUESTOS I SON AGENTES COCCIDIOSTATICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853531919 DE3531919A1 (de) | 1985-09-07 | 1985-09-07 | Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2001292A6 true ES2001292A6 (es) | 1988-05-01 |
Family
ID=6280327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8601669A Expired ES2001292A6 (es) | 1985-09-07 | 1986-09-05 | Procedimiento para preparar hexahidro-1,2,4-triazin-3,5-dionas substituidas |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4782056A (es) |
| EP (1) | EP0215354B1 (es) |
| JP (1) | JPS6261972A (es) |
| KR (1) | KR940001729B1 (es) |
| AT (1) | ATE62901T1 (es) |
| AU (1) | AU588052B2 (es) |
| BG (1) | BG45552A3 (es) |
| CA (1) | CA1290332C (es) |
| CS (1) | CS258144B2 (es) |
| DD (1) | DD249477A5 (es) |
| DE (2) | DE3531919A1 (es) |
| DK (1) | DK167395B1 (es) |
| ES (1) | ES2001292A6 (es) |
| HU (1) | HU196594B (es) |
| IL (1) | IL79951A0 (es) |
| NZ (1) | NZ217471A (es) |
| PH (1) | PH22566A (es) |
| PL (1) | PL147476B1 (es) |
| PT (1) | PT83306B (es) |
| SU (1) | SU1517760A3 (es) |
| ZA (1) | ZA866756B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1986000072A1 (en) * | 1984-06-12 | 1986-01-03 | Fmc Corporation | Herbicidal 2-aryl-1,2,4-triazine-3,5(2h,4h)-diones and sulfur analogs thereof |
| DE3814323A1 (de) * | 1988-04-28 | 1989-11-09 | Hoechst Ag | Wasserloesliche zubereitungen von coccidiostatica |
| GB8810185D0 (en) * | 1988-04-29 | 1988-06-02 | Glaxo Group Ltd | Chemical compounds |
| CN1044905A (zh) * | 1989-02-16 | 1990-08-29 | 赫彻斯特股份公司 | 鱼和昆虫寄生虫对抗剂 |
| CA2012004A1 (en) * | 1989-03-15 | 1990-09-15 | Frank Ellis | Chemical compounds |
| DE4030042A1 (de) * | 1990-05-17 | 1991-11-21 | Bayer Ag | Verwendung von substituierten 1,2,4-triazindionen |
| EP0476439A1 (de) * | 1990-09-18 | 1992-03-25 | Bayer Ag | Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung |
| DE4120138A1 (de) * | 1991-06-19 | 1992-12-24 | Bayer Ag | Substituierte hexahydro-1,2,4-triazindione, verfahren zu ihrer herstellung, zwischenprodukte dafuer und ihre verwendung |
| US5994355A (en) | 1993-10-15 | 1999-11-30 | Takeda Chemical Industries, Ltd. | 1, 2, 4-Triazin-3-one derivatives, production and use thereof |
| US5436243A (en) * | 1993-11-17 | 1995-07-25 | Research Triangle Institute Duke University | Aminoanthraquinone derivatives to combat multidrug resistance |
| EP0831088B1 (en) * | 1996-08-30 | 2002-11-27 | Takeda Schering-Plough Animal Health K.K. | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents |
| TW450964B (en) | 1997-08-29 | 2001-08-21 | Takeda Schering Plough Animal | Triazine derivatives, their production and use |
| HUE025013T2 (hu) | 2009-01-12 | 2016-04-28 | Pfizer Ltd | Szulfonamid-származékok |
| JP5872552B2 (ja) | 2010-07-09 | 2016-03-01 | ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ | 化学化合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2149645A1 (de) * | 1970-10-07 | 1972-09-14 | Pfizer | 2-Phenyl-as-triazin-3.5-(2H,4H)-dione und die Verwendung dieser Verbindungen zur Bekaempfung der Coccidiose |
| GB1448696A (en) * | 1973-05-29 | 1976-09-08 | Pfizer | 2-phqnyl-astriazine-3,4-2h,4h-diones |
| DE2722537A1 (de) * | 1977-05-18 | 1978-11-23 | Hoechst Ag | Substituierte 2-phenyl-1,2,4-triazin-3,5-(2h,4h)-dione, verfahren zu ihrer herstellung und sie enthaltende coccidiostatische mittel |
| IL62151A (en) * | 1981-02-18 | 1984-10-31 | Abic B M | Hexahydro-1,2,4-triazine-3,5-dione derivatives,their preparation and feed compositions,drinking water and pharmaceutical compositions containing said derivatives |
| DE3408924A1 (de) * | 1984-03-12 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
| CA1244024A (en) * | 1984-08-01 | 1988-11-01 | Gustaaf M. Boeckx | .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES |
-
1985
- 1985-09-07 DE DE19853531919 patent/DE3531919A1/de not_active Withdrawn
-
1986
- 1986-08-28 EP EP86111924A patent/EP0215354B1/de not_active Expired - Lifetime
- 1986-08-28 AT AT86111924T patent/ATE62901T1/de not_active IP Right Cessation
- 1986-08-28 DE DE8686111924T patent/DE3678884D1/de not_active Expired - Fee Related
- 1986-09-02 BG BG076342A patent/BG45552A3/xx unknown
- 1986-09-04 CS CS866428A patent/CS258144B2/cs unknown
- 1986-09-04 PT PT83306A patent/PT83306B/pt not_active IP Right Cessation
- 1986-09-05 NZ NZ217471A patent/NZ217471A/xx unknown
- 1986-09-05 ZA ZA866756A patent/ZA866756B/xx unknown
- 1986-09-05 AU AU62368/86A patent/AU588052B2/en not_active Ceased
- 1986-09-05 PL PL1986261303A patent/PL147476B1/pl unknown
- 1986-09-05 DD DD86294182A patent/DD249477A5/de not_active IP Right Cessation
- 1986-09-05 SU SU864028140A patent/SU1517760A3/ru active
- 1986-09-05 IL IL79951A patent/IL79951A0/xx not_active IP Right Cessation
- 1986-09-05 JP JP61208110A patent/JPS6261972A/ja active Pending
- 1986-09-05 HU HU863863A patent/HU196594B/hu not_active IP Right Cessation
- 1986-09-05 ES ES8601669A patent/ES2001292A6/es not_active Expired
- 1986-09-05 US US06/903,752 patent/US4782056A/en not_active Expired - Fee Related
- 1986-09-05 CA CA000517636A patent/CA1290332C/en not_active Expired - Fee Related
- 1986-09-05 DK DK425486A patent/DK167395B1/da not_active IP Right Cessation
- 1986-09-05 PH PH34225A patent/PH22566A/en unknown
- 1986-09-06 KR KR1019860007475A patent/KR940001729B1/ko not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US4782056A (en) | 1988-11-01 |
| DK425486A (da) | 1987-03-08 |
| PH22566A (en) | 1988-10-17 |
| DD249477A5 (de) | 1987-09-09 |
| DK167395B1 (da) | 1993-10-25 |
| SU1517760A3 (ru) | 1989-10-23 |
| CS258144B2 (en) | 1988-07-15 |
| CA1290332C (en) | 1991-10-08 |
| KR940001729B1 (ko) | 1994-03-05 |
| DK425486D0 (da) | 1986-09-05 |
| PL261303A1 (en) | 1988-03-17 |
| EP0215354B1 (de) | 1991-04-24 |
| ZA866756B (en) | 1987-04-29 |
| PL147476B1 (en) | 1989-06-30 |
| HU196594B (en) | 1988-12-28 |
| KR870003077A (ko) | 1987-04-15 |
| CS642886A2 (en) | 1987-11-12 |
| AU588052B2 (en) | 1989-09-07 |
| IL79951A0 (en) | 1986-12-31 |
| JPS6261972A (ja) | 1987-03-18 |
| DE3531919A1 (de) | 1987-03-19 |
| EP0215354A2 (de) | 1987-03-25 |
| DE3678884D1 (de) | 1991-05-29 |
| BG45552A3 (bg) | 1989-06-15 |
| AU6236886A (en) | 1987-03-12 |
| PT83306B (pt) | 1989-05-12 |
| PT83306A (de) | 1986-10-01 |
| EP0215354A3 (en) | 1989-01-18 |
| NZ217471A (en) | 1989-06-28 |
| ATE62901T1 (de) | 1991-05-15 |
| HUT45031A (en) | 1988-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-09-05 |
|
| FD1A | Patent lapsed |
Effective date: 20000601 |