ES2001427A6 - Procedimiento de preparacion de un nuevo complejo solido apropiado para obtener proteinas insolubilizadas, aislar yno determinar fosfatos organicos y catalizar sitesis peptidicas. - Google Patents
Procedimiento de preparacion de un nuevo complejo solido apropiado para obtener proteinas insolubilizadas, aislar yno determinar fosfatos organicos y catalizar sitesis peptidicas.Info
- Publication number
- ES2001427A6 ES2001427A6 ES8601920A ES8601920A ES2001427A6 ES 2001427 A6 ES2001427 A6 ES 2001427A6 ES 8601920 A ES8601920 A ES 8601920A ES 8601920 A ES8601920 A ES 8601920A ES 2001427 A6 ES2001427 A6 ES 2001427A6
- Authority
- ES
- Spain
- Prior art keywords
- enzymes
- alumina
- insolubilized
- phosphate
- functional group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 6
- 108090000790 Enzymes Proteins 0.000 title abstract 6
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 title abstract 5
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 4
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 239000002253 acid Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
EL PROCEDIMIENTO DESCRITO PREPARA UN NUEVO COMPLEJO SOLIDO FIJANDO SOBRE ALUMINA AL MENOS UN GRUPO FUNCIONAL FOSFATO DE UN COMPUESTO BIFUNCIONAL O POLIFUNCIONAL QUE CONTIENE AL MENOS UN GRUPO FUNCIONAL FOSFATO Y AL MENOS UN GRUPO QUIMICAMENTE REACTIVO CAPAZ DE FORMAR ENLACE COVALENTE CON MOLECULAS PROTEICAS, ESPECIALMENTE ENZIMAS. LAS PROTEINAS INSOLUBILIZADAS SE OBTIENEN LIGANDO DICHO COMPLEJO SOLIDO, POR ENLACE COVALENTE, A UNA PROTEINA DE MANERA QUE LOS GRUPOS QUIMICAMENTE REACTIVOS DEL COMPLEJO REACCIONEN CON LOS GRUPOS REACTIVOS DE LA PROTEINA QUE SE HA DE HACER INSOLUBLE. EL AISLAMIENTO Y/O DETERMINACION DE FOSFATOS ORGANICOS SE EFECTUA PONIENDOLOS EN CONTACTO CON DICHO COMPLEJO SOLIDO, EN MEDIO ACUOSO, A PH 2-8,5 Y LIBERANDO DESPUES DICHOS FOSFATOS DEL COMPLEJO FORMADO. LAS PROTEINAS INSOLUBILIZADAS, PARTICULARMENTE ENZIMAS, SON ESPECIALMENTE UTILES PARA LA CATALISIS DE SINTESIS PEPTIDICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8513740A FR2587358B1 (fr) | 1985-09-17 | 1985-09-17 | Procede d'insolubilisation d'enzymes par fixation sur des complexes alumine-phosphates organiques et enzymes insolubilisees obtenues par ce procede, nouveaux supports d'enzymes et leur procede de preparation et applications desdites enzymes insolubilisees |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2001427A6 true ES2001427A6 (es) | 1988-05-16 |
Family
ID=9322967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8601920A Expired ES2001427A6 (es) | 1985-09-17 | 1986-09-16 | Procedimiento de preparacion de un nuevo complejo solido apropiado para obtener proteinas insolubilizadas, aislar yno determinar fosfatos organicos y catalizar sitesis peptidicas. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0218506B1 (es) |
| JP (1) | JPS62115286A (es) |
| AT (1) | ATE41664T1 (es) |
| DE (1) | DE3662524D1 (es) |
| DK (1) | DK444786A (es) |
| ES (1) | ES2001427A6 (es) |
| FR (1) | FR2587358B1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2221466A (en) * | 1988-03-09 | 1990-02-07 | Aluminum Co Of America | Biologically reactive particles with biological, therapeutic and chromatographic applications |
| JP2615421B2 (ja) * | 1994-03-11 | 1997-05-28 | 工業技術院長 | 結晶性有機リン酸アルミニウム塩 |
| FR2773170B1 (fr) * | 1997-12-31 | 2000-10-13 | Ase & Bio Soc Civ | Enzymes immobilisees sur un support a base d'alumine, leurs procedes de preparation et leurs applications |
| FR2773171B1 (fr) * | 1997-12-31 | 2000-10-13 | Ase & Bio Soc Civ | Enzymes immobilisees sur un support, leurs procedes de preparation et leurs applications |
| FR2773172B1 (fr) * | 1997-12-31 | 2000-10-13 | Ase & Bio Soc Civ | Enzymes immobilisees sur un support mineral, leurs procedes de preparation et leurs applications |
| US6461858B1 (en) * | 1998-01-26 | 2002-10-08 | Pharm-Eco Laboratories, Inc. | Enzyme activated supports for enantiomeric separations |
| FR2813025B1 (fr) * | 2000-08-17 | 2002-11-29 | Inst Francais Du Petrole | Materiaux comportant des groupements organiques contenant du phosphore lie par l'intermediaire d'atomes d'oxygenes a un oxyde mineral |
| CN108976259A (zh) * | 2017-06-01 | 2018-12-11 | 上海凯赛生物技术研发中心有限公司 | 一种磷酸吡哆醛的合成方法 |
| TWI870373B (zh) * | 2018-12-28 | 2025-01-21 | 大陸商中國石油化工科技開發有限公司 | 一種擬薄水鋁石、其製造方法及其應用 |
-
1985
- 1985-09-17 FR FR8513740A patent/FR2587358B1/fr not_active Expired
-
1986
- 1986-09-15 EP EP86402014A patent/EP0218506B1/fr not_active Expired
- 1986-09-15 AT AT86402014T patent/ATE41664T1/de not_active IP Right Cessation
- 1986-09-15 DE DE8686402014T patent/DE3662524D1/de not_active Expired
- 1986-09-16 ES ES8601920A patent/ES2001427A6/es not_active Expired
- 1986-09-16 DK DK444786A patent/DK444786A/da not_active Application Discontinuation
- 1986-09-17 JP JP61220832A patent/JPS62115286A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2587358B1 (fr) | 1987-12-24 |
| ATE41664T1 (de) | 1989-04-15 |
| EP0218506B1 (fr) | 1989-03-22 |
| DK444786D0 (da) | 1986-09-16 |
| DK444786A (da) | 1987-03-18 |
| EP0218506A1 (fr) | 1987-04-15 |
| FR2587358A1 (fr) | 1987-03-20 |
| JPS62115286A (ja) | 1987-05-26 |
| DE3662524D1 (en) | 1989-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000204 |