ES2002127A6 - Procedimiento para extraer los colagenos placentarios - Google Patents

Procedimiento para extraer los colagenos placentarios

Info

Publication number
ES2002127A6
ES2002127A6 ES8601542A ES8601542A ES2002127A6 ES 2002127 A6 ES2002127 A6 ES 2002127A6 ES 8601542 A ES8601542 A ES 8601542A ES 8601542 A ES8601542 A ES 8601542A ES 2002127 A6 ES2002127 A6 ES 2002127A6
Authority
ES
Spain
Prior art keywords
precipitated
acid
extraction
neutral
collagen preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601542A
Other languages
English (en)
Inventor
Jean Louis Tayot
Michel Tardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Publication of ES2002127A6 publication Critical patent/ES2002127A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA EXTRAER LOS COLAGENOS PLACENTARIOS, EN EL QUE SE SOMETE PLACENTA HUMANA O ANIMAL A UNA DIGESTION ENZIMATICA MODERADA, ESPECIALMENTE CON PEPSINA O PH ACIDO, Y LUEGO, DESPUES DE SEPARACION DEL TEJIDO RESIDUAL, SE PRECIPITAN LAS IMPUREZAS A PH ACIDO MODERADO, SE PRECIPITA EL COLAGENO A PH NEUTRO, SE LE VUELVE A DISOLVER Y SE PRECIPITAN LAS IMPUREZAS RESIDUALES A PH ACIDO. EL COLAGENO OBTENIDO PUEDE SER LLEVADO A PH NEUTRO Y SECADO A LA FORMA DE FIBRAS, PUDIENDO PREPARARSE CON EL GELES Y SOLUCIONES PERFECTAMENTE TRANSPARENTES, FISIOLOGICAS Y HEMOCOMPATIBLES. APLICACIONES A LAS LENTILLAS DE CONTACTO Y A LOS IMPLANTES.
ES8601542A 1985-09-02 1986-09-01 Procedimiento para extraer los colagenos placentarios Expired ES2002127A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8513004A FR2586703B1 (fr) 1985-09-02 1985-09-02 Procede d'extraction de collagenes placentaires, collagenes obtenus notamment sous forme de gels ou de solutions et leurs applications

Publications (1)

Publication Number Publication Date
ES2002127A6 true ES2002127A6 (es) 1988-07-16

Family

ID=9322543

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601542A Expired ES2002127A6 (es) 1985-09-02 1986-09-01 Procedimiento para extraer los colagenos placentarios

Country Status (6)

Country Link
EP (1) EP0214035B1 (es)
JP (1) JP2563232B2 (es)
CA (1) CA1340222C (es)
DE (1) DE3682551D1 (es)
ES (1) ES2002127A6 (es)
FR (1) FR2586703B1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214505B (it) * 1987-03-12 1990-01-18 Gentili Ist Spa Procedimento per la preparazione di collageno e prodotti cosi'ottenuto.
FR2617763B1 (fr) * 1987-07-07 1989-12-01 Essilor Int Procede de fabrication de lentille de contact en un polymere proteique naturel, par moulage avant reticulation
US4876332A (en) * 1987-10-08 1989-10-24 Regents Of The Univeristy Of Minnesota Polypeptides with type IV collagen activity
FR2715405B1 (fr) * 1994-01-24 1996-04-05 Imedex Procédé pour l'élimination des prions dans des collagènes et collagènes ainsi obtenus.
FR2720945B1 (fr) 1994-06-08 1996-08-30 Coletica Membrane collagénique anti-adhérence post-opératoire.
FR2777284B1 (fr) * 1998-04-10 2000-05-26 Hamza Mansour Procede de sterilisation d'un collagene natif en milieu liquide, collagene natif sterile obtenu, compositions le contenant et applications
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
RU2715715C1 (ru) * 2019-03-06 2020-03-03 Общество с ограниченной ответственностью фирмы "Имтек" Стерильный прозрачный концентрированный раствор биосовместимого коллагена, способ его получения и применения
CN111592592A (zh) * 2020-03-02 2020-08-28 内蒙古林宁医疗科技有限公司 人胎盘不同类型胶原蛋白选择性提取制备方法和使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2462222A1 (de) * 1974-02-02 1976-05-06 Trommsdorff Fa H Loesliches, natives human-kollagen, dessen nicht-helikale peptide teilweise oder vollstaendig abgetrennt sind
DE2616939C3 (de) * 1976-04-17 1981-10-15 Böttger GmbH Pharmazeutische und Kosmetische Präparate, 1000 Berlin Verwendung von Placentaextraktrückständen und Verfahren zur Herstellung eines kollagenhaltigen Placentaextrakts
US4268131A (en) * 1979-04-11 1981-05-19 Opticol Corporation Fiber collagen contact lens
DE2929144A1 (de) * 1979-07-19 1981-02-12 Behringwerke Ag Verfahren zur herstellung von kollagen
FR2516927B1 (fr) * 1981-11-26 1986-05-23 Merieux Fond Procede de preparation industrielle de materiaux collageniques a partir de tissus placentaires humains, materiaux collageniques humains obtenus, leur application comme biomateriaux
US4505855A (en) * 1982-09-30 1985-03-19 Massachusetts General Hospital Transparent non-fibrilized collagen material by ultracentrifugation

Also Published As

Publication number Publication date
EP0214035A1 (fr) 1987-03-11
DE3682551D1 (de) 1992-01-02
JPS6253927A (ja) 1987-03-09
CA1340222C (en) 1998-12-15
JP2563232B2 (ja) 1996-12-11
FR2586703B1 (fr) 1989-12-01
FR2586703A1 (fr) 1987-03-06
EP0214035B1 (fr) 1991-11-21

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-01

PC1A Transfer granted

Owner name: PASTEUR MERIEUX SERUMS ET VACCINS (TITULAR DEL 50%