ES2003179A6 - Un metodo para producir celuilas cuyas respuestas inmunologicas han sido moduladas. - Google Patents

Un metodo para producir celuilas cuyas respuestas inmunologicas han sido moduladas.

Info

Publication number
ES2003179A6
ES2003179A6 ES8603411A ES8603411A ES2003179A6 ES 2003179 A6 ES2003179 A6 ES 2003179A6 ES 8603411 A ES8603411 A ES 8603411A ES 8603411 A ES8603411 A ES 8603411A ES 2003179 A6 ES2003179 A6 ES 2003179A6
Authority
ES
Spain
Prior art keywords
cellules
modulated
produce
immunological responses
isoxantopterin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8603411A
Other languages
English (en)
Inventor
Michael G Goodman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of ES2003179A6 publication Critical patent/ES2003179A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

COMPRENDE LA PREPARACION DE UNA COMPOSICION QUE CONTIENE UNA CANTIDAD EFECTIVA DE UN ISOXANTOPTERIN©8©ALDOGLICOSIDO DE FORMULA (I), DONDE R1 ES H, ALQUILO, ARILO, OPCIONALMENTE SUSTITUIDOS, Y R2 ES UN ALDOGLICOSIDO; SEGUIDO DE MANTENER EN CONTACTO DICHA COMPOSICION CON LAS CELULAS ADECUADAS HASTA QUE ESTAS MODULEN SU RESPUESTA. LAS COMPOSICIONES CONTENIENDO LA ISOXANTOPTERINA (I) SON TAMBIEN UTILES PARA PRODUCIR LEUCOCITOS CON RESPUESTA CELULAR POTENCIADA Y PARA PRODUCIR CELULAS CON SECRECION POTENCIADA DE ANTICUERPOS CONTRA UN INMUNOGENO PRE©SELECCIONADO.
ES8603411A 1985-12-13 1986-12-12 Un metodo para producir celuilas cuyas respuestas inmunologicas han sido moduladas. Expired ES2003179A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80888685A 1985-12-13 1985-12-13

Publications (1)

Publication Number Publication Date
ES2003179A6 true ES2003179A6 (es) 1988-10-16

Family

ID=25200016

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603411A Expired ES2003179A6 (es) 1985-12-13 1986-12-12 Un metodo para producir celuilas cuyas respuestas inmunologicas han sido moduladas.

Country Status (15)

Country Link
EP (1) EP0248084B1 (es)
JP (1) JPS63502113A (es)
AT (1) ATE82771T1 (es)
AU (1) AU592848B2 (es)
CA (1) CA1300506C (es)
DE (1) DE3687169T2 (es)
DK (1) DK598986A (es)
ES (1) ES2003179A6 (es)
FI (1) FI873496A7 (es)
GR (1) GR862901B (es)
IL (1) IL80928A (es)
NZ (1) NZ218618A (es)
PT (1) PT83921B (es)
WO (1) WO1987003617A1 (es)
ZA (1) ZA869297B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880784A (en) * 1987-12-21 1989-11-14 Brigham Young University Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
ZA908001B (en) * 1989-10-11 1991-08-28 Merrell Dow Pharma Inosine/guanosine derivatives as immunosuppressive agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081410B1 (es) * 1970-01-06 1974-08-23 Ciba Geigy Ag
JPS5399319A (en) * 1977-02-09 1978-08-30 Hidematsu Hirai Novel qualitative and quantitative detecting method and detecting body for antgenic substance
JPS57200862A (en) * 1981-06-05 1982-12-09 Fuji Photo Film Co Ltd Mutilayer analysis element utilizing unique binding reaction
US4435504A (en) * 1982-07-15 1984-03-06 Syva Company Immunochromatographic assay with support having bound "MIP" and second enzyme
US4643992A (en) * 1982-11-09 1987-02-17 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
GB8305197D0 (en) * 1983-02-24 1983-03-30 Amersham Int Plc Assay methods

Also Published As

Publication number Publication date
JPS63502113A (ja) 1988-08-18
EP0248084A1 (en) 1987-12-09
AU592848B2 (en) 1990-01-25
IL80928A0 (en) 1987-03-31
IL80928A (en) 1992-08-18
PT83921B (pt) 1989-01-17
DE3687169T2 (de) 1993-04-01
EP0248084B1 (en) 1992-11-25
AU6848287A (en) 1987-06-30
FI873496L (fi) 1987-08-12
FI873496A0 (fi) 1987-08-12
GR862901B (en) 1987-04-15
PT83921A (en) 1987-01-01
DK598986A (da) 1987-06-14
CA1300506C (en) 1992-05-12
DE3687169D1 (de) 1993-01-07
ZA869297B (en) 1987-11-25
FI873496A7 (fi) 1987-08-12
ATE82771T1 (de) 1992-12-15
WO1987003617A1 (en) 1987-06-18
NZ218618A (en) 1989-03-29
DK598986D0 (da) 1986-12-12
EP0248084A4 (en) 1988-03-30

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-12-12