ES2003687A6 - Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina. - Google Patents
Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina.Info
- Publication number
- ES2003687A6 ES2003687A6 ES8700425A ES8700425A ES2003687A6 ES 2003687 A6 ES2003687 A6 ES 2003687A6 ES 8700425 A ES8700425 A ES 8700425A ES 8700425 A ES8700425 A ES 8700425A ES 2003687 A6 ES2003687 A6 ES 2003687A6
- Authority
- ES
- Spain
- Prior art keywords
- suspensions
- amoxicillin
- injectable
- injectable amoxicillin
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title abstract 2
- 229960003022 amoxicillin Drugs 0.000 title 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 title 1
- 239000000725 suspension Substances 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 2
- 229960004920 amoxicillin trihydrate Drugs 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARACION DE UN PREPARADO FARMACEUTICO INYECTABLE DE AMOXICILINA, CONSISTE EN MOLES EL TRIHIDRATO DE AMOXICILINA HASTA OBTENER UN POLVO FINO CON UN TAMAÑO DE PARTICULAS COMPRENDIDO ENTRE 1 Y 25 MICRONES Y A CONTINUACION SUSPENDERLO EN UN DISOLVENTE ADECUADO TAL COMO AGUA. LA CONCENTRACION DEL TRIHIDRATO DE AMOXICILINA EN EL PREPARADO INYECTABLE OSCILA ENTRE 100 MG DE ACTIVIDAD/ML Y 1.000 MG DE ACTIVIDAD/ML. EL PREPARADO INYECTABLE DE LA INVENCION TIENE APLICACION EN LA INDUSTRIA FARMACEUTICA YA QUE LA AMOXICILINA ES UN CONOCIDO ANTIBIOTICO DE AMPLIO ESPECTRO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8602332A FR2594334B1 (fr) | 1986-02-20 | 1986-02-20 | Composition pharmaceutique injectable a base d'amoxicilline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2003687A6 true ES2003687A6 (es) | 1988-11-01 |
Family
ID=9332343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8700425A Expired ES2003687A6 (es) | 1986-02-20 | 1987-02-19 | Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina. |
Country Status (13)
| Country | Link |
|---|---|
| BE (1) | BE1000535A4 (es) |
| CH (1) | CH668706A5 (es) |
| DE (1) | DE3705349A1 (es) |
| EG (1) | EG18455A (es) |
| ES (1) | ES2003687A6 (es) |
| FR (1) | FR2594334B1 (es) |
| GB (1) | GB2186797B (es) |
| GR (1) | GR870278B (es) |
| IT (1) | IT1202567B (es) |
| LU (1) | LU86781A1 (es) |
| MY (1) | MY101146A (es) |
| NL (1) | NL8700416A (es) |
| ZA (1) | ZA871225B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007523125A (ja) * | 2004-02-24 | 2007-08-16 | サンド・アクチエンゲゼルシヤフト | アモキシシリンインスタント顆粒 |
| CN102614294B (zh) * | 2011-01-27 | 2015-02-25 | 瑞普（天津）生物药业有限公司 | 一种复方阿莫西林混悬注射剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3969524A (en) * | 1974-08-13 | 1976-07-13 | Hoffmann-La Roche Inc. | Stable amoxicillin dosage form |
| US3996355A (en) * | 1975-01-02 | 1976-12-07 | American Home Products Corporation | Permanent suspension pharmaceutical dosage form |
| GB1532993A (en) * | 1975-03-07 | 1978-11-22 | Beecham Group Ltd | Injectable antibiotic compositions |
| FR2469179A1 (fr) * | 1979-11-08 | 1981-05-22 | Beecham Group Ltd | Composition pharmaceutique pour injection renfermant une penicilline |
| EP0080862B1 (en) * | 1981-12-02 | 1985-09-25 | Beecham Group Plc | Pharmaceutical formulation comprising beta-lactam antibiotics |
-
1986
- 1986-02-20 FR FR8602332A patent/FR2594334B1/fr not_active Expired - Lifetime
-
1987
- 1987-02-11 MY MYPI87000127A patent/MY101146A/en unknown
- 1987-02-19 GB GB8703883A patent/GB2186797B/en not_active Expired - Lifetime
- 1987-02-19 CH CH617/87A patent/CH668706A5/fr not_active IP Right Cessation
- 1987-02-19 DE DE19873705349 patent/DE3705349A1/de not_active Ceased
- 1987-02-19 IT IT19426/87A patent/IT1202567B/it active
- 1987-02-19 NL NL8700416A patent/NL8700416A/nl active Search and Examination
- 1987-02-19 ES ES8700425A patent/ES2003687A6/es not_active Expired
- 1987-02-19 EG EG90/87A patent/EG18455A/xx active
- 1987-02-19 ZA ZA871225A patent/ZA871225B/xx unknown
- 1987-02-19 LU LU86781A patent/LU86781A1/fr unknown
- 1987-02-20 BE BE8700157A patent/BE1000535A4/fr not_active IP Right Cessation
- 1987-02-20 GR GR870278A patent/GR870278B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2594334B1 (fr) | 1990-01-12 |
| GB8703883D0 (en) | 1987-03-25 |
| GB2186797A (en) | 1987-08-26 |
| NL8700416A (nl) | 1987-09-16 |
| BE1000535A4 (fr) | 1989-01-24 |
| MY101146A (en) | 1991-07-31 |
| LU86781A1 (fr) | 1987-09-15 |
| FR2594334A1 (fr) | 1987-08-21 |
| GR870278B (en) | 1987-06-16 |
| DE3705349A1 (de) | 1987-08-27 |
| CH668706A5 (fr) | 1989-01-31 |
| ZA871225B (en) | 1987-10-28 |
| IT1202567B (it) | 1989-02-09 |
| EG18455A (en) | 1992-12-30 |
| IT8719426A0 (it) | 1987-02-19 |
| GB2186797B (en) | 1990-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20110225 |