ES2005447A6 - Procedimiento de preparacion de una perfeccionada raza mutante de "bordetella bronchiseptica", util para una vacuna atenuada viva destinada a la proteccion contra infeccion de la "b.bronchiseptica". - Google Patents

Procedimiento de preparacion de una perfeccionada raza mutante de "bordetella bronchiseptica", util para una vacuna atenuada viva destinada a la proteccion contra infeccion de la "b.bronchiseptica".

Info

Publication number
ES2005447A6
ES2005447A6 ES8703251A ES8703251A ES2005447A6 ES 2005447 A6 ES2005447 A6 ES 2005447A6 ES 8703251 A ES8703251 A ES 8703251A ES 8703251 A ES8703251 A ES 8703251A ES 2005447 A6 ES2005447 A6 ES 2005447A6
Authority
ES
Spain
Prior art keywords
bronchiseptica
live attenuated
vaccine
useful
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8703251A
Other languages
English (en)
Inventor
Katsumi Kume
Toyotsugu Nakal
Hiroshi Nishizawa
Takashi Yoshikawa
Hirofumi Danbar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Publication of ES2005447A6 publication Critical patent/ES2005447A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/825—Bacterial vaccine for porcine species, e.g. swine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/83—Drug, bio-affecting and body treating compositions involving temperature-sensitive mutant bacterium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE UNA RAZA MUTANTE DE LA <B. BRONCHISEPTICA>.DE ACUERDO CON ESTE PROCEDIMIENTO SE SOMETE UNA RAZA DE LA B. BROCHISEPTICA A UNA MUTACION INDUCIDA, EL AISLAMIENTO DE UN MUTANTE DOTADO DE LOS MARCADORES GENETICOS CONSISTENTES EN SER POR LO MENOS SENSIBLE A LA TEMPERATURA (DESARROLLADO A 42GC), RESISTENTE AL ACIDO NALIDIXICO Y NEGATIVO RESPECTO A TOXINAS DERMONECROTICAS TERMOINESTABLES, EL CULTIVO DE LA RAZA DE B. BRONCHISEPTICA EN PLACA DE AGAR BORDETGENGOU QUE CONTIENE ACIDO NALIDIXICO A 42GC, LA ULTERIOR RECOGIDA DE UN ORGANISMO MORFOLOGICAMENTE SEMEJANTE A LA FASE I, LA REPETICION DE LOS PROCEDIMIENTOS DE CULTIVO EN LA PLACA DE AGAR BORDETGENGOU Y RECOGIDA DE LOS ORGANISMOS DE LA FASE I, Y LA CONVERSION DE ESTOS ORGANISMOS EN UNO DE FASE I NEGATIVO EN CAPACIDAD PRODUCTORA DE TOXINAS DERMONECROTICAS TERMOINESTABLES, DOTADO DE ANTIGENO CAPSULAR COMPLETO.
ES8703251A 1986-11-27 1987-11-13 Procedimiento de preparacion de una perfeccionada raza mutante de "bordetella bronchiseptica", util para una vacuna atenuada viva destinada a la proteccion contra infeccion de la "b.bronchiseptica". Expired ES2005447A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61280890A JP2537042B2 (ja) 1986-11-27 1986-11-27 ボルデテラ・ブロンキセプチカ感染症生菌ワクチン用原株の製造法および生菌ワクチン

Publications (1)

Publication Number Publication Date
ES2005447A6 true ES2005447A6 (es) 1989-03-01

Family

ID=17631367

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8703251A Expired ES2005447A6 (es) 1986-11-27 1987-11-13 Procedimiento de preparacion de una perfeccionada raza mutante de "bordetella bronchiseptica", util para una vacuna atenuada viva destinada a la proteccion contra infeccion de la "b.bronchiseptica".

Country Status (13)

Country Link
US (1) US4770875A (es)
JP (1) JP2537042B2 (es)
BE (1) BE1000255A4 (es)
BR (1) BR8706053A (es)
CA (1) CA1315226C (es)
DE (1) DE3740182C2 (es)
DK (1) DK620087A (es)
ES (1) ES2005447A6 (es)
FR (1) FR2607392B1 (es)
GB (1) GB2200844B (es)
IL (1) IL84258A (es)
IT (1) IT1223171B (es)
NL (1) NL194960C (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine
IT1236971B (it) * 1989-11-03 1993-05-07 Eniricerche Spa Regione promotore dei geni codificanti le subunita' piliniche fim2, fm3 e fimx di bordetella pertussis e loro impiego per l'espressione di geni che codificano una proteina di interesse.
EP0680337A4 (en) * 1993-01-12 1997-07-30 Anthony George Gristina METHODS AND COMPOSITIONS FOR DIRECT APPLICATION WITH HIGH CONCENTRATION OF ANTIBODIES, PRODUCING PASSIVE IMMUNITY.
US8337861B2 (en) * 2003-01-09 2012-12-25 The Trustees Of The University Of Pennsylvania Compositions, methods and kits for enhancing the immunogenicity of a bacterial vaccine vector

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016253A (en) * 1975-04-02 1977-04-05 Iowa State University Research Foundation, Inc. Vaccine for immunization of swine against Bordetella bronchiseptica infection and method of use
US4530832A (en) * 1978-12-07 1985-07-23 Schering Corporation Method of vaccination for prevention of Bordetella bronchiseptica infection
US4225583A (en) * 1978-12-07 1980-09-30 Iowa State University Research Foundation, Inc. Intra-respiratory vaccine for prevention of Bordetella bronchiseptica infection and method of use
EP0012718B1 (en) * 1978-12-07 1981-09-16 Iowa State University Research Foundation, Inc. Intra-respiratory vaccine, modified bacteria strain used in it, vaccine dose form and process for preparing it
JPS5953828B2 (ja) * 1981-08-10 1984-12-27 健 清水 ボルデテラ・プロンヒセブティカ感染症生菌ワクチン用改良原株の作出法および生菌ワクチン
FR2578424B1 (fr) * 1985-03-08 1988-07-08 Agronomique Inst Nat Rech Souches mutantes, vaccinantes de bacteries, leur procede d'obtention, et preparations vaccinales les contenant

Also Published As

Publication number Publication date
CA1315226C (en) 1993-03-30
FR2607392A1 (fr) 1988-06-03
IT1223171B (it) 1990-09-12
DE3740182C2 (de) 1995-03-16
NL8702728A (nl) 1988-06-16
BE1000255A4 (fr) 1988-09-27
DK620087A (da) 1988-05-28
IL84258A (en) 1991-05-12
NL194960C (nl) 2003-09-02
IL84258A0 (en) 1988-03-31
BR8706053A (pt) 1988-06-28
FR2607392B1 (fr) 1991-05-03
GB8727820D0 (en) 1987-12-31
IT8722791A0 (it) 1987-11-27
US4770875A (en) 1988-09-13
GB2200844A (en) 1988-08-17
GB2200844B (en) 1991-04-10
JP2537042B2 (ja) 1996-09-25
DK620087D0 (da) 1987-11-26
DE3740182A1 (de) 1988-08-18
JPS63135335A (ja) 1988-06-07
NL194960B (nl) 2003-05-01

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-11-13

FD1A Patent lapsed

Effective date: 20061114