ES2007948A6 - Procedimiento para la obtencion de derivados propargilguanidicos. - Google Patents

Procedimiento para la obtencion de derivados propargilguanidicos.

Info

Publication number
ES2007948A6
ES2007948A6 ES8802117A ES8802117A ES2007948A6 ES 2007948 A6 ES2007948 A6 ES 2007948A6 ES 8802117 A ES8802117 A ES 8802117A ES 8802117 A ES8802117 A ES 8802117A ES 2007948 A6 ES2007948 A6 ES 2007948A6
Authority
ES
Spain
Prior art keywords
derivatives
propargylguanidine
preparation
integer
acid anions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8802117A
Other languages
English (en)
Inventor
Vinas Antonio Buxade
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Vinas SA
Original Assignee
Laboratorios Vinas SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Vinas SA filed Critical Laboratorios Vinas SA
Priority to ES8802117A priority Critical patent/ES2007948A6/es
Priority to DE8989500060T priority patent/DE68902887T2/de
Priority to JP1131220A priority patent/JPH0225469A/ja
Priority to AT89500060T priority patent/ATE80622T1/de
Priority to EP89500060A priority patent/EP0350422B1/en
Publication of ES2007948A6 publication Critical patent/ES2007948A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS PROPARGILGUANIDINICOS DE FORMULA I DONDE: X ES UN ANION FARMACEUTICAMENTE ACEPTABLES; A ES UN NUMERO ENTERO DE 1 A 5; B ES UN NUMERO ENTERO DE 1 A 7; C ES CERO O UN NUMERO ENTERO DE 1 A 4; Y DE 2A - C, PARA ANIONES DE ACIDOS MONOVALENTES, ES A - C, PARA ANIONES DE ACIDOS DIVALENTES, Y ES CERO O 2 CUANDO C ES CERO, ITBASADO EN LA REACCION DE LA N-CIANO-NK-(2-((4-METIL-5-IMIDAZOLIL-METILTIO-ETIL)-NL-PROPARGIL-GUANIDINA CON UN COMPUESTO DE ZINC- QUE CONTIENE EL ANION X, O CON UN ORGANOZINC.
ES8802117A 1988-07-06 1988-07-06 Procedimiento para la obtencion de derivados propargilguanidicos. Expired ES2007948A6 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES8802117A ES2007948A6 (es) 1988-07-06 1988-07-06 Procedimiento para la obtencion de derivados propargilguanidicos.
DE8989500060T DE68902887T2 (de) 1988-07-06 1989-05-23 Propargylguanidin-derivate und verfahren zu deren herstellung.
JP1131220A JPH0225469A (ja) 1988-07-06 1989-05-23 プロパルギルグアニジン誘導体及びその製造方法
AT89500060T ATE80622T1 (de) 1988-07-06 1989-05-23 Propargylguanidin-derivate und verfahren zu deren herstellung.
EP89500060A EP0350422B1 (en) 1988-07-06 1989-05-23 Propargylguanidine derivatives and process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES8802117A ES2007948A6 (es) 1988-07-06 1988-07-06 Procedimiento para la obtencion de derivados propargilguanidicos.

Publications (1)

Publication Number Publication Date
ES2007948A6 true ES2007948A6 (es) 1989-07-01

Family

ID=8257175

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8802117A Expired ES2007948A6 (es) 1988-07-06 1988-07-06 Procedimiento para la obtencion de derivados propargilguanidicos.

Country Status (5)

Country Link
EP (1) EP0350422B1 (es)
JP (1) JPH0225469A (es)
AT (1) ATE80622T1 (es)
DE (1) DE68902887T2 (es)
ES (1) ES2007948A6 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9004328D0 (en) * 1990-02-27 1990-04-25 Glaxo Group Ltd Chemical compounds
GB9009240D0 (en) * 1990-04-25 1990-06-20 Glaxo Group Ltd Chemical compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1110251A (en) * 1977-06-03 1981-10-06 Ronnie R. Crenshaw N-cyano-n'- 2-¬(4-methyl-5- imidazolyl)methylthio|ethyl - n"-alkynylguanidines h.sub.2 receptor blocking agents
US4381395A (en) * 1981-04-03 1983-04-26 Sk & F Lab Co. Process for preparing an imidazole derivative

Also Published As

Publication number Publication date
DE68902887T2 (de) 1993-03-18
DE68902887D1 (de) 1992-10-22
EP0350422B1 (en) 1992-09-16
EP0350422A1 (en) 1990-01-10
JPH0225469A (ja) 1990-01-26
ATE80622T1 (de) 1992-10-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103